5h5i - Revision history

OCA at 07:24, 9 August 2023

OCA — Wed, 09 Aug 2023 07:24:09 GMT

←Older revision		Revision as of 07:24, 9 August 2023
Line 3:		Line 3:
	<StructureSection load='5h5i' size='340' side='right'caption='[[5h5i]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='5h5i' size='340' side='right'caption='[[5h5i]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5h5i]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Staar Staar~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H5I OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5H5I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5h5i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MRSA252 Staphylococcus aureus subsp. aureus MRSA252]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5H5I FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GDP:GUANOSINE~~-~~5-DIPHOSPHATE'>GDP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[5h5g\|5h5g]], [[5h5h\|5h5h]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~"><~~b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">ftsZ, SAR1162 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=282458 STAAR])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5h5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h5i OCA], [https://pdbe.org/5h5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5h5i RCSB], [https://www.ebi.ac.uk/pdbsum/5h5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5h5i ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5h5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h5i OCA], [~~http~~://pdbe.org/5h5i PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5h5i RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5h5i PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5h5i ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/FTSZ_STAAR FTSZ_STAAR]] Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	+	[https://www.uniprot.org/uniprot/FTSZ_STAAR FTSZ_STAAR] Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Staar~~]]	+	[[Category: Staphylococcus aureus subsp. aureus MRSA252]]
-	[[Category: Fujita, J]]	+	[[Category: Fujita J]]
-	[[Category: Harada, R]]	+	[[Category: Harada R]]
-	[[Category: Inoue, T]]	+	[[Category: Inoue T]]
-	[[Category: Maeda, Y]]	+	[[Category: Maeda Y]]
-	[[Category: Matsumura, H]]	+	[[Category: Matsumura H]]
-	[[Category: Mizohata, E]]	+	[[Category: Mizohata E]]
-	[[Category: Saito, Y]]	+	[[Category: Saito Y]]
-	[[Category: Shigeta, Y]]	+	[[Category: Shigeta Y]]
-	~~[[Category: Cell cycle]]~~	+
-	~~[[Category: Gtpase]]~~	+
-	~~[[Category: Protofilament]]~~	+
-	~~[[Category: Tubulin/ftsz family~~]]	+

OCA at 06:53, 20 May 2020

OCA — Wed, 20 May 2020 06:53:07 GMT

←Older revision		Revision as of 06:53, 20 May 2020
Line 1:		Line 1:

	==Staphylococcus aureus FtsZ-GDP R29A mutant in R state==		==Staphylococcus aureus FtsZ-GDP R29A mutant in R state==
-	<StructureSection load='5h5i' size='340' side='right' caption='[[5h5i]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='5h5i' size='340' side='right'caption='[[5h5i]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5h5i]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H5I OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5H5I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5h5i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staar Staar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H5I OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5H5I FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5h5g\|5h5g]], [[5h5h\|5h5h]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5h5g\|5h5g]], [[5h5h\|5h5h]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5h5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h5i OCA], [http://pdbe.org/5h5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h5i RCSB], [http://www.ebi.ac.uk/pdbsum/5h5i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h5i ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftsZ, SAR1162 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=282458 STAAR])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5h5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h5i OCA], [http://pdbe.org/5h5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h5i RCSB], [http://www.ebi.ac.uk/pdbsum/5h5i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h5i ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 5h5i" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5h5i" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cell division protein 3D structures\|Cell division protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Staar]]
	[[Category: Fujita, J]]		[[Category: Fujita, J]]
	[[Category: Harada, R]]		[[Category: Harada, R]]

OCA at 13:41, 24 May 2017

OCA — Wed, 24 May 2017 13:41:22 GMT

←Older revision		Revision as of 13:41, 24 May 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5h5i is ~~ON HOLD until Paper~~ Publication	+	==Staphylococcus aureus FtsZ-GDP R29A mutant in R state==
		+	<StructureSection load='5h5i' size='340' side='right' caption='[[5h5i]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5h5i]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5H5I FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5h5g\|5h5g]], [[5h5h\|5h5h]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5h5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h5i OCA], [http://pdbe.org/5h5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h5i RCSB], [http://www.ebi.ac.uk/pdbsum/5h5i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h5i ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FTSZ_STAAR FTSZ_STAAR]] Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The tubulin-homolog protein FtsZ is essential for bacterial cell division. FtsZ polymerizes to form protofilaments that assemble into a contractile ring-shaped structure in the presence of GTP. Recent studies showed that FtsZ treadmilling coupled with the GTPase activity drives cell wall synthesis and bacterial cell division. The treadmilling caused by assembly and disassembly of FtsZ links to a conformational change of the monomer from a tense (T) to a relaxed (R) state, but considerable controversy still remains concerning the mechanism. In this study, we report crystal structures of FtsZ from Staphylococcus aureus corresponding to the T and R state conformations in the same crystal, indicating the structural equilibrium of the two state. The two structures identified a key residue Arg29, whose importance was also confirmed by our modified MD simulations. Crystal structures of the R29A mutant showed T and R state-like conformations with slight but important structural changes compared to those of wild-type. Collectively, these data provide new insights for understanding how intramolecular interactions are related to the structural transition of FtsZ.

-	~~Authors:~~ Fujita, J., Harada, R., Maeda, Y., Saito, Y., Mizohata, E., Inoue, T., Shigeta, Y., Matsumura, H.	+	Identification of the key interactions in structural transition pathway of FtsZ from Staphylococcus aureus.,Fujita J, Harada R, Maeda Y, Saito Y, Mizohata E, Inoue T, Shigeta Y, Matsumura H J Struct Biol. 2017 May;198(2):65-73. doi: 10.1016/j.jsb.2017.04.008. Epub 2017, Apr 27. PMID:28456664<ref>PMID:28456664</ref>

-	~~Description: Staphylococcus aureus FtsZ-GDP R29A mutant in R state~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category~~: ~~Mizohata, E]]~~	+	<div class="pdbe-citations 5h5i" style="background-color:#fffaf0;"></div>
-	~~[[Category: Inoue, T]]~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Fujita, J]]		[[Category: Fujita, J]]
-	[[Category: Shigeta, Y]]
-	[[Category: Saito, Y]]
	[[Category: Harada, R]]		[[Category: Harada, R]]
-	[[Category: ~~Matsumura~~, H]]	+	[[Category: Inoue, T]]
	[[Category: Maeda, Y]]		[[Category: Maeda, Y]]
		+	[[Category: Matsumura, H]]
		+	[[Category: Mizohata, E]]
		+	[[Category: Saito, Y]]
		+	[[Category: Shigeta, Y]]
		+	[[Category: Cell cycle]]
		+	[[Category: Gtpase]]
		+	[[Category: Protofilament]]
		+	[[Category: Tubulin/ftsz family]]

OCA at 09:25, 9 March 2017

OCA — Thu, 09 Mar 2017 09:25:25 GMT

←Older revision		Revision as of 09:25, 9 March 2017
Line 7:		Line 7:
	Description: Staphylococcus aureus FtsZ-GDP R29A mutant in R state		Description: Staphylococcus aureus FtsZ-GDP R29A mutant in R state
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Inoue, T]]
-	[[Category: Matsumura, H]]
-	[[Category: Maeda, Y]]
	[[Category: Mizohata, E]]		[[Category: Mizohata, E]]
		+	[[Category: Inoue, T]]
	[[Category: Fujita, J]]		[[Category: Fujita, J]]
	[[Category: Shigeta, Y]]		[[Category: Shigeta, Y]]
	[[Category: Saito, Y]]		[[Category: Saito, Y]]
	[[Category: Harada, R]]		[[Category: Harada, R]]
		+	[[Category: Matsumura, H]]
		+	[[Category: Maeda, Y]]

OCA: Protected "5h5i" [edit=sysop:move=sysop]

OCA — Fri, 09 Dec 2016 13:46:04 GMT

Protected "5h5i" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:46, 9 December 2016

OCA: New page: '''Unreleased structure''' The entry 5h5i is ON HOLD until Paper Publication Authors: Fujita, J., Harada, R., Maeda, Y., Saito, Y., Mizohata, E., Inoue, T., Shigeta, Y., Matsumura, H. ...

OCA — Fri, 09 Dec 2016 13:46:03 GMT

New page: '''Unreleased structure''' The entry 5h5i is ON HOLD until Paper Publication Authors: Fujita, J., Harada, R., Maeda, Y., Saito, Y., Mizohata, E., Inoue, T., Shigeta, Y., Matsumura, H. ...

New page

'''Unreleased structure'''

The entry 5h5i is ON HOLD until Paper Publication

Authors: Fujita, J., Harada, R., Maeda, Y., Saito, Y., Mizohata, E., Inoue, T., Shigeta, Y., Matsumura, H.

Description: Staphylococcus aureus FtsZ-GDP R29A mutant in R state
[[Category: Unreleased Structures]]
[[Category: Inoue, T]]
[[Category: Matsumura, H]]
[[Category: Maeda, Y]]
[[Category: Mizohata, E]]
[[Category: Fujita, J]]
[[Category: Shigeta, Y]]
[[Category: Saito, Y]]
[[Category: Harada, R]]