5hq5 - Revision history

OCA at 10:50, 16 August 2023

OCA — Wed, 16 Aug 2023 10:50:38 GMT

←Older revision		Revision as of 10:50, 16 August 2023
Line 3:		Line 3:
	<StructureSection load='5hq5' size='340' side='right'caption='[[5hq5]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='5hq5' size='340' side='right'caption='[[5hq5]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5hq5]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HQ5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5HQ5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5hq5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HQ5 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=64Q:7~~-~~METHYL-N-(O-TOLYL)-[1~~,~~2,4]TRIAZOLO~~[~~4,3-A~~]~~PYRIMIDIN-5-AMINE'>64Q</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[5hq6\|5hq6]], [[5hq7\|5hq7]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=64Q:7-METHYL-N-(O-TOLYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIMIDIN-5-AMINE'>64Q</scene></td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~"><b>[[~~Gene\|Gene:]~~]~~</b~~></td>~~<td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hq5 OCA], [https://pdbe.org/5hq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hq5 RCSB], [https://www.ebi.ac.uk/pdbsum/5hq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hq5 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5hq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hq5 OCA], [~~http~~://pdbe.org/5hq5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5hq5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5hq5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5hq5 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Disease ==		== Disease ==
-	[~~[http~~://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>	+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).	+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).

	==See Also==		==See Also==
Line 20:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chen~~, T T~~]]	+	[[Category: Chen TT]]
-	[[Category: Xu~~, Y C]]~~	+	[[Category: Xu YC]]
-	~~[[Category: Brd4]]~~	+
-	~~[[Category: Transcription~~]]	+

OCA at 08:27, 27 May 2020

OCA — Wed, 27 May 2020 08:27:27 GMT

←Older revision		Revision as of 08:27, 27 May 2020
Line 1:		Line 1:

	==Crystal structure of fragment bound with Brd4==		==Crystal structure of fragment bound with Brd4==
-	<StructureSection load='5hq5' size='340' side='right' caption='[[5hq5]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='5hq5' size='340' side='right'caption='[[5hq5]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5hq5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5HQ5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5hq5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HQ5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=64Q:7-METHYL-N-(O-TOLYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIMIDIN-5-AMINE'>64Q</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=64Q:7-METHYL-N-(O-TOLYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIMIDIN-5-AMINE'>64Q</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5hq6\|5hq6]], [[5hq7\|5hq7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5hq6\|5hq6]], [[5hq7\|5hq7]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5hq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hq5 OCA], [http://pdbe.org/5hq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hq5 RCSB], [http://www.ebi.ac.uk/pdbsum/5hq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hq5 ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hq5 OCA], [http://pdbe.org/5hq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hq5 RCSB], [http://www.ebi.ac.uk/pdbsum/5hq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hq5 ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
Line 12:		Line 13:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).		[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
		+
		+	==See Also==
		+	*[[Bromodomain-containing protein 3D structures\|Bromodomain-containing protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Chen, T T]]		[[Category: Chen, T T]]
	[[Category: Xu, Y C]]		[[Category: Xu, Y C]]
	[[Category: Brd4]]		[[Category: Brd4]]
	[[Category: Transcription]]		[[Category: Transcription]]

OCA at 23:42, 25 January 2017

OCA — Wed, 25 Jan 2017 23:42:26 GMT

←Older revision		Revision as of 23:42, 25 January 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5hq5 is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of fragment bound with Brd4==
-		+	<StructureSection load='5hq5' size='340' side='right' caption='[[5hq5]], [[Resolution\|resolution]] 1.60Å' scene=''>
-	~~Authors~~: ~~Chen~~, T.T., Xu, Y.C.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5hq5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HQ5 FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure~~ of ~~fragment bound~~ with ~~Brd4~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=64Q:7-METHYL-N-(O-TOLYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIMIDIN-5-AMINE'>64Q</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5hq6\|5hq6]], [[5hq7\|5hq7]]</td></tr>
-	[[Category: Xu, Y.C]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hq5 OCA], [http://pdbe.org/5hq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hq5 RCSB], [http://www.ebi.ac.uk/pdbsum/5hq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hq5 ProSAT]</span></td></tr>
-	[[Category: ~~Chen, T.T~~]]	+	</table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Chen, T T]]
		+	[[Category: Xu, Y C]]
		+	[[Category: Brd4]]
		+	[[Category: Transcription]]

OCA at 19:00, 23 June 2016

OCA — Thu, 23 Jun 2016 19:00:38 GMT

←Older revision		Revision as of 19:00, 23 June 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5hq5 is ON HOLD	+	The entry 5hq5 is ON HOLD until Paper Publication

	Authors: Chen, T.T., Xu, Y.C.		Authors: Chen, T.T., Xu, Y.C.

OCA: Protected "5hq5" [edit=sysop:move=sysop]

OCA — Thu, 28 Jan 2016 01:05:44 GMT

Protected "5hq5" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:05, 28 January 2016

OCA: New page: '''Unreleased structure''' The entry 5hq5 is ON HOLD Authors: Chen, T.T., Xu, Y.C. Description: Crystal structure of fragment bound with Brd4 Category: Unreleased Structures [[Cate...

OCA — Thu, 28 Jan 2016 01:05:43 GMT

New page: '''Unreleased structure''' The entry 5hq5 is ON HOLD Authors: Chen, T.T., Xu, Y.C. Description: Crystal structure of fragment bound with Brd4 Category: Unreleased Structures [[Cate...

New page

'''Unreleased structure'''

The entry 5hq5 is ON HOLD

Authors: Chen, T.T., Xu, Y.C.

Description: Crystal structure of fragment bound with Brd4
[[Category: Unreleased Structures]]
[[Category: Xu, Y.C]]
[[Category: Chen, T.T]]