5hxd - Revision history

OCA at 10:58, 16 August 2023

OCA — Wed, 16 Aug 2023 10:58:15 GMT

←Older revision		Revision as of 10:58, 16 August 2023
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	<StructureSection load='5hxd' size='340' side='right'caption='[[5hxd]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='5hxd' size='340' side='right'caption='[[5hxd]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5hxd]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Eco57 Eco57~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HXD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5HXD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5hxd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HXD FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>~~, ~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~mpaA, Z2448, ECs1905 ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=83334 ECO57])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5hxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hxd OCA], [~~http~~://pdbe.org/5hxd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5hxd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5hxd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5hxd ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hxd OCA], [https://pdbe.org/5hxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hxd RCSB], [https://www.ebi.ac.uk/pdbsum/5hxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hxd ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/MPAA_ECO57 MPAA_ECO57]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Eco57~~]]	+	[[Category: Escherichia coli O157:H7]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bai, G]]	+	[[Category: Bai G]]
-	[[Category: Kang, X]]	+	[[Category: Kang X]]
-	[[Category: Li, Z]]	+	[[Category: Li Z]]
-	[[Category: Liu, X]]	+	[[Category: Liu X]]
-	[[Category: Ma, Y]]	+	[[Category: Ma Y]]
-	[[Category: Mu, S]]	+	[[Category: Mu S]]
-	[[Category: Yuan, Z]]	+	[[Category: Yuan Z]]
-	[[Category: Zhang, X]]	+	[[Category: Zhang X]]
-	[[Category: Zhao, J]]	+	[[Category: Zhao J]]
-	~~[[Category: Escherichia coli o157]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Mpaa]]~~	+
-	~~[[Category: Murein-tripeptide amidase~~]]	+

OCA at 08:35, 27 May 2020

OCA — Wed, 27 May 2020 08:35:43 GMT

←Older revision		Revision as of 08:35, 27 May 2020
Line 1:		Line 1:

	==Crystal structure of murein-tripeptide amidase MpaA from Escherichia coli O157==		==Crystal structure of murein-tripeptide amidase MpaA from Escherichia coli O157==
-	<StructureSection load='5hxd' size='340' side='right' caption='[[5hxd]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='5hxd' size='340' side='right'caption='[[5hxd]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5hxd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HXD OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5HXD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5hxd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Eco57 Eco57]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HXD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HXD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5hxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hxd OCA], [http://pdbe.org/5hxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hxd RCSB], [http://www.ebi.ac.uk/pdbsum/5hxd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hxd ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mpaA, Z2448, ECs1905 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83334 ECO57])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hxd OCA], [http://pdbe.org/5hxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hxd RCSB], [http://www.ebi.ac.uk/pdbsum/5hxd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hxd ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Eco57]]
		+	[[Category: Large Structures]]
	[[Category: Bai, G]]		[[Category: Bai, G]]
	[[Category: Kang, X]]		[[Category: Kang, X]]

OCA at 09:23, 10 March 2017

OCA — Fri, 10 Mar 2017 09:23:27 GMT

←Older revision		Revision as of 09:23, 10 March 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5hxd is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of murein-tripeptide amidase MpaA from Escherichia coli O157==
		+	<StructureSection load='5hxd' size='340' side='right' caption='[[5hxd]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5hxd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HXD FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hxd OCA], [http://pdbe.org/5hxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hxd RCSB], [http://www.ebi.ac.uk/pdbsum/5hxd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hxd ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Peptidoglycan (PG) is an essential component of the cell wall, and undergoes reconstruction by various PG hydrolases during cell growth, development and division. The murein- tripeptide (Mtp) amidase MpaA belongs to PG hydrolase family and is responsible for cleaving the gamma-D-Glu-meso-Dap amide bond in the Mtp released during PG turnover. The current paper reports the crystal structure of MpaA from Escherichia coli (E. coli) O157 at 2.6 A resolution. The asymmetric unit consists of two protein molecules and each monomer represents the common alpha/beta fold of metallo-carboxypeptidases (MCP). The Tyr133-Asp143 loop appears to mediate the entrance and binding of the substrate into the active groove. A structural comparison of MpaA with its homologue from Vibrio harveyi showed that MpaA has narrower active pocket entrance with a smaller surface opening, which is determined by the Val204-Thr211 loop. The reported structure provides a starting point for the molecular mechanism of MpaA in a significant human pathogen.

-	~~Authors:~~ Ma, Y., Bai, G., ~~Zhang, X.~~, Zhao, J., Yuan, Z~~., Kang~~, X.~~, Li, Z., Mu, S., Liu, X~~.	+	Crystal Structure of Murein-Tripeptide Amidase MpaA from Escherichia coli O157 at 2.6 A Resolution.,Ma Y, Bai G, Cui Y, Zhao J, Yuan Z, Liu X Protein Pept Lett. 2016 Nov 28. PMID:27894248<ref>PMID:27894248</ref>

-	~~Description: Crystal structure~~ of ~~murein-tripeptide amidase MpaA from Escherichia coli O157~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 5hxd" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Bai, G]]		[[Category: Bai, G]]
-	[[Category: ~~Zhang~~, X]]	+	[[Category: Kang, X]]
-	[[Category: Mu, S]]	+	[[Category: Li, Z]]
	[[Category: Liu, X]]		[[Category: Liu, X]]
	[[Category: Ma, Y]]		[[Category: Ma, Y]]
-	[[Category: ~~Zhao~~, ~~J]]~~	+	[[Category: Mu, S]]
-	~~[[Category: Li, Z~~]]	+
	[[Category: Yuan, Z]]		[[Category: Yuan, Z]]
-	[[Category: ~~Kang~~, X]]	+	[[Category: Zhang, X]]
		+	[[Category: Zhao, J]]
		+	[[Category: Escherichia coli o157]]
		+	[[Category: Hydrolase]]
		+	[[Category: Mpaa]]
		+	[[Category: Murein-tripeptide amidase]]

OCA at 01:17, 21 February 2016

OCA — Sun, 21 Feb 2016 01:17:03 GMT

←Older revision		Revision as of 01:17, 21 February 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5hxd is ON HOLD	+	The entry 5hxd is ON HOLD until Paper Publication

	Authors: Ma, Y., Bai, G., Zhang, X., Zhao, J., Yuan, Z., Kang, X., Li, Z., Mu, S., Liu, X.		Authors: Ma, Y., Bai, G., Zhang, X., Zhao, J., Yuan, Z., Kang, X., Li, Z., Mu, S., Liu, X.

OCA: Protected "5hxd" [edit=sysop:move=sysop]

OCA — Wed, 10 Feb 2016 15:50:41 GMT

Protected "5hxd" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:50, 10 February 2016

OCA: New page: '''Unreleased structure''' The entry 5hxd is ON HOLD Authors: Ma, Y., Bai, G., Zhang, X., Zhao, J., Yuan, Z., Kang, X., Li, Z., Mu, S., Liu, X. Description: Crystal structure of murein...

OCA — Wed, 10 Feb 2016 15:50:39 GMT

New page: '''Unreleased structure''' The entry 5hxd is ON HOLD Authors: Ma, Y., Bai, G., Zhang, X., Zhao, J., Yuan, Z., Kang, X., Li, Z., Mu, S., Liu, X. Description: Crystal structure of murein...

New page

'''Unreleased structure'''

The entry 5hxd is ON HOLD

Authors: Ma, Y., Bai, G., Zhang, X., Zhao, J., Yuan, Z., Kang, X., Li, Z., Mu, S., Liu, X.

Description: Crystal structure of murein-tripeptide amidase MpaA from Escherichia coli O157
[[Category: Unreleased Structures]]
[[Category: Bai, G]]
[[Category: Zhang, X]]
[[Category: Mu, S]]
[[Category: Liu, X]]
[[Category: Ma, Y]]
[[Category: Zhao, J]]
[[Category: Li, Z]]
[[Category: Yuan, Z]]
[[Category: Kang, X]]