5hzy - Revision history

OCA at 09:16, 20 March 2024

OCA — Wed, 20 Mar 2024 09:16:27 GMT

←Older revision		Revision as of 09:16, 20 March 2024
Line 9:		Line 9:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/RAVZ_LEGPH RAVZ_LEGPH] Cysteine protease effector that inhibits host cell autophagy by targeting lipid-conjugated ATG8 family proteins on pre-autophagosomal structures (PubMed:23112293, PubMed:29458288, PubMed:32686895, PubMed:31722778, PubMed:31719622, PubMed:33298241, PubMed:26343456, PubMed:28395732). Specifically hydrolyzes the amide bond between the C-terminal glycine residue and an adjacent aromatic residue in ATG8 proteins conjugated to phosphatidylethanolamine (PE), producing an ATG8 protein that cannot be reconjugated by host ATG7 and ATG3 (PubMed:23112293, PubMed:29458288, PubMed:32686895, PubMed:26343456, PubMed:28395732). Mechanistically, Ravz interacts with ATG8 proteins conjugated to PE via its LIR motifs, extracts them from the membrane of autophagosomes and integrates the PE part into its own lipid-binding site (PubMed:28395732). It then removes the lipid component of the ATG8 protein (PubMed:28395732). Also able to mediate delipidation of ATG8 proteins conjugated to phosphatidylserine (PS) during non-canonical autophagy (PubMed:33909989). Inhibits host ubiquitin recruitment to bacteria-containing vacuoles, suggesting that it is able to mediate delipidation of other proteins in addition to ATG8 proteins (PubMed:28971069). It is however not involved in the exclusion of autophagy adapters from bacteria-containing vacuoles decorated with ubiquitin (PubMed:32482642).<ref>PMID:23112293</ref> <ref>PMID:26343456</ref> <ref>PMID:28395732</ref> <ref>PMID:28971069</ref> <ref>PMID:29458288</ref> <ref>PMID:31719622</ref> <ref>PMID:31722778</ref> <ref>PMID:32482642</ref> <ref>PMID:32686895</ref> <ref>PMID:33298241</ref> <ref>PMID:33909989</ref>		[https://www.uniprot.org/uniprot/RAVZ_LEGPH RAVZ_LEGPH] Cysteine protease effector that inhibits host cell autophagy by targeting lipid-conjugated ATG8 family proteins on pre-autophagosomal structures (PubMed:23112293, PubMed:29458288, PubMed:32686895, PubMed:31722778, PubMed:31719622, PubMed:33298241, PubMed:26343456, PubMed:28395732). Specifically hydrolyzes the amide bond between the C-terminal glycine residue and an adjacent aromatic residue in ATG8 proteins conjugated to phosphatidylethanolamine (PE), producing an ATG8 protein that cannot be reconjugated by host ATG7 and ATG3 (PubMed:23112293, PubMed:29458288, PubMed:32686895, PubMed:26343456, PubMed:28395732). Mechanistically, Ravz interacts with ATG8 proteins conjugated to PE via its LIR motifs, extracts them from the membrane of autophagosomes and integrates the PE part into its own lipid-binding site (PubMed:28395732). It then removes the lipid component of the ATG8 protein (PubMed:28395732). Also able to mediate delipidation of ATG8 proteins conjugated to phosphatidylserine (PS) during non-canonical autophagy (PubMed:33909989). Inhibits host ubiquitin recruitment to bacteria-containing vacuoles, suggesting that it is able to mediate delipidation of other proteins in addition to ATG8 proteins (PubMed:28971069). It is however not involved in the exclusion of autophagy adapters from bacteria-containing vacuoles decorated with ubiquitin (PubMed:32482642).<ref>PMID:23112293</ref> <ref>PMID:26343456</ref> <ref>PMID:28395732</ref> <ref>PMID:28971069</ref> <ref>PMID:29458288</ref> <ref>PMID:31719622</ref> <ref>PMID:31722778</ref> <ref>PMID:32482642</ref> <ref>PMID:32686895</ref> <ref>PMID:33298241</ref> <ref>PMID:33909989</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Hosts utilize macroautophagy/autophagy to clear invading bacteria; however, bacteria have also developed a specific mechanism to survive by manipulating the host cell autophagy mechanism. One pathogen, Legionella pneumophila, can hinder host cell autophagy by using the specific effector protein RavZ that cleaves phosphatidylethanolamine-conjugated LC3 on the phagophore membrane. However, the detailed molecular mechanisms associated with the function of RavZ have hitherto remained unclear. Here, we report on the biochemical characteristics of the RavZ-LC3 interaction, the solution structure of the 1:2 complex between RavZ and LC3, and crystal structures of RavZ showing different conformations of the active site loop without LC3. Based on our biochemical, structural, and cell-based analyses of RavZ and LC3, both distant flexible N- and C-terminal regions containing LC3-interacting region (LIR) motifs are important for substrate recognition. These results suggest a novel mechanism of RavZ action on the phagophore membrane and lay the groundwork for understanding how bacterial pathogens can survive autophagy.
-
-	The 1:2 complex between RavZ and LC3 reveals a mechanism for deconjugation of LC3 on the phagophore membrane.,Kwon DH, Kim S, Jung YO, Roh KH, Kim L, Kim BW, Hong SB, Lee IY, Song JH, Lee WC, Choi EJ, Hwang KY, Song HK Autophagy. 2017 Jan 2;13(1):70-81. doi: 10.1080/15548627.2016.1243199. Epub 2016 , Oct 28. PMID:27791457<ref>PMID:27791457</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5hzy" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:18, 23 August 2023

OCA — Wed, 23 Aug 2023 08:18:40 GMT

←Older revision		Revision as of 08:18, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='5hzy' size='340' side='right'caption='[[5hzy]], [[Resolution\|resolution]] 2.55Å' scene=''>		<StructureSection load='5hzy' size='340' side='right'caption='[[5hzy]], [[Resolution\|resolution]] 2.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5hzy]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Legph Legph~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HZY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5HZY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5hzy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._Philadelphia_1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HZY FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~lpg1683 (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=272624 LEGPH])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.548Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5hzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hzy OCA], [~~http~~://pdbe.org/5hzy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5hzy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5hzy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5hzy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hzy OCA], [https://pdbe.org/5hzy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hzy RCSB], [https://www.ebi.ac.uk/pdbsum/5hzy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hzy ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/RAVZ_LEGPH RAVZ_LEGPH] Cysteine protease effector that inhibits host cell autophagy by targeting lipid-conjugated ATG8 family proteins on pre-autophagosomal structures (PubMed:23112293, PubMed:29458288, PubMed:32686895, PubMed:31722778, PubMed:31719622, PubMed:33298241, PubMed:26343456, PubMed:28395732). Specifically hydrolyzes the amide bond between the C-terminal glycine residue and an adjacent aromatic residue in ATG8 proteins conjugated to phosphatidylethanolamine (PE), producing an ATG8 protein that cannot be reconjugated by host ATG7 and ATG3 (PubMed:23112293, PubMed:29458288, PubMed:32686895, PubMed:26343456, PubMed:28395732). Mechanistically, Ravz interacts with ATG8 proteins conjugated to PE via its LIR motifs, extracts them from the membrane of autophagosomes and integrates the PE part into its own lipid-binding site (PubMed:28395732). It then removes the lipid component of the ATG8 protein (PubMed:28395732). Also able to mediate delipidation of ATG8 proteins conjugated to phosphatidylserine (PS) during non-canonical autophagy (PubMed:33909989). Inhibits host ubiquitin recruitment to bacteria-containing vacuoles, suggesting that it is able to mediate delipidation of other proteins in addition to ATG8 proteins (PubMed:28971069). It is however not involved in the exclusion of autophagy adapters from bacteria-containing vacuoles decorated with ubiquitin (PubMed:32482642).<ref>PMID:23112293</ref> <ref>PMID:26343456</ref> <ref>PMID:28395732</ref> <ref>PMID:28971069</ref> <ref>PMID:29458288</ref> <ref>PMID:31719622</ref> <ref>PMID:31722778</ref> <ref>PMID:32482642</ref> <ref>PMID:32686895</ref> <ref>PMID:33298241</ref> <ref>PMID:33909989</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Legph~~]]	+	[[Category: Legionella pneumophila subsp. pneumophila str. Philadelphia 1]]
-	[[Category: Hong~~, S B~~]]	+	[[Category: Hong SB]]
-	[[Category: Kim, B W]]	+	[[Category: Kim B-W]]
-	[[Category: Kim, L]]	+	[[Category: Kim L]]
-	[[Category: Kwon~~, D H~~]]	+	[[Category: Kwon DH]]
-	[[Category: Song~~, H K]]~~	+	[[Category: Song HK]]
-	~~[[Category: Atg4b]]~~	+
-	~~[[Category: Atg8]]~~	+
-	~~[[Category: Autophagy]]~~	+
-	~~[[Category: Deconjugating enzyme]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Protease~~]]	+

OCA at 08:38, 27 May 2020

OCA — Wed, 27 May 2020 08:38:59 GMT

←Older revision		Revision as of 08:38, 27 May 2020
Line 1:		Line 1:

	==Crystal structure of the legionella pneumophila effector protein RavZ - P6322==		==Crystal structure of the legionella pneumophila effector protein RavZ - P6322==
-	<StructureSection load='5hzy' size='340' side='right' caption='[[5hzy]], [[Resolution\|resolution]] 2.55Å' scene=''>	+	<StructureSection load='5hzy' size='340' side='right'caption='[[5hzy]], [[Resolution\|resolution]] 2.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5hzy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HZY OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5HZY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5hzy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Legph Legph]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HZY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HZY FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5hzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hzy OCA], [http://pdbe.org/5hzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hzy RCSB], [http://www.ebi.ac.uk/pdbsum/5hzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hzy ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lpg1683 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272624 LEGPH])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hzy OCA], [http://pdbe.org/5hzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hzy RCSB], [http://www.ebi.ac.uk/pdbsum/5hzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hzy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Legph]]
	[[Category: Hong, S B]]		[[Category: Hong, S B]]
	[[Category: Kim, B W]]		[[Category: Kim, B W]]

OCA at 09:11, 17 May 2017

OCA — Wed, 17 May 2017 09:11:58 GMT

←Older revision		Revision as of 09:11, 17 May 2017
Line 6:		Line 6:
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hzy OCA], [http://pdbe.org/5hzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hzy RCSB], [http://www.ebi.ac.uk/pdbsum/5hzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hzy ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hzy OCA], [http://pdbe.org/5hzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hzy RCSB], [http://www.ebi.ac.uk/pdbsum/5hzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hzy ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Hosts utilize macroautophagy/autophagy to clear invading bacteria; however, bacteria have also developed a specific mechanism to survive by manipulating the host cell autophagy mechanism. One pathogen, Legionella pneumophila, can hinder host cell autophagy by using the specific effector protein RavZ that cleaves phosphatidylethanolamine-conjugated LC3 on the phagophore membrane. However, the detailed molecular mechanisms associated with the function of RavZ have hitherto remained unclear. Here, we report on the biochemical characteristics of the RavZ-LC3 interaction, the solution structure of the 1:2 complex between RavZ and LC3, and crystal structures of RavZ showing different conformations of the active site loop without LC3. Based on our biochemical, structural, and cell-based analyses of RavZ and LC3, both distant flexible N- and C-terminal regions containing LC3-interacting region (LIR) motifs are important for substrate recognition. These results suggest a novel mechanism of RavZ action on the phagophore membrane and lay the groundwork for understanding how bacterial pathogens can survive autophagy.
		+
		+	The 1:2 complex between RavZ and LC3 reveals a mechanism for deconjugation of LC3 on the phagophore membrane.,Kwon DH, Kim S, Jung YO, Roh KH, Kim L, Kim BW, Hong SB, Lee IY, Song JH, Lee WC, Choi EJ, Hwang KY, Song HK Autophagy. 2017 Jan 2;13(1):70-81. doi: 10.1080/15548627.2016.1243199. Epub 2016 , Oct 28. PMID:27791457<ref>PMID:27791457</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5hzy" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 19:48, 9 December 2016

OCA — Fri, 09 Dec 2016 19:48:27 GMT

←Older revision		Revision as of 19:48, 9 December 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5hzy ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of the legionella pneumophila effector protein RavZ - P6322==
-		+	<StructureSection load='5hzy' size='340' side='right' caption='[[5hzy]], [[Resolution\|resolution]] 2.55Å' scene=''>
-	~~Authors~~: ~~Kwon, D~~.H.~~, Kim, L., Kim, B~~.-W.~~, Hong, S~~.B.~~, Song, H~~.K.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5hzy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HZY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HZY FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of the legionella pneumophila effector protein RavZ~~ -~~P6322~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hzy OCA], [http://pdbe.org/5hzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hzy RCSB], [http://www.ebi.ac.uk/pdbsum/5hzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hzy ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[Category: ~~Kwon~~, ~~D.H~~]]	+	__TOC__
-	[[Category: Kim, B.-W]]	+	</StructureSection>
		+	[[Category: Hong, S B]]
		+	[[Category: Kim, B W]]
	[[Category: Kim, L]]		[[Category: Kim, L]]
-	[[Category: Song, H.K]]	+	[[Category: Kwon, D H]]
-	[[Category: ~~Hong, S.B~~]]	+	[[Category: Song, H K]]
		+	[[Category: Atg4b]]
		+	[[Category: Atg8]]
		+	[[Category: Autophagy]]
		+	[[Category: Deconjugating enzyme]]
		+	[[Category: Hydrolase]]
		+	[[Category: Protease]]

OCA at 10:55, 14 September 2016

OCA — Wed, 14 Sep 2016 10:55:30 GMT

←Older revision		Revision as of 10:55, 14 September 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5hzy is ON HOLD	+	The entry 5hzy is ON HOLD until Paper Publication

	Authors: Kwon, D.H., Kim, L., Kim, B.-W., Hong, S.B., Song, H.K.		Authors: Kwon, D.H., Kim, L., Kim, B.-W., Hong, S.B., Song, H.K.

OCA at 01:22, 21 February 2016

OCA — Sun, 21 Feb 2016 01:22:11 GMT

←Older revision		Revision as of 01:22, 21 February 2016
Line 3:		Line 3:
	The entry 5hzy is ON HOLD		The entry 5hzy is ON HOLD

-	Authors: ~~Do Hoon~~ Kwon, ~~Leehyeon~~ Kim, ~~Byeong-Won~~ Kim, ~~Seung Beom~~ Hong, ~~Hyun Kyu~~ Song	+	Authors: Kwon, D.H., Kim, L., Kim, B.-W., Hong, S.B., Song, H.K.

	Description: Crystal structure of the legionella pneumophila effector protein RavZ -P6322		Description: Crystal structure of the legionella pneumophila effector protein RavZ -P6322
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Do Hoon~~ Kwon, ~~Leehyeon~~ Kim, ~~Byeong~~-~~Won~~ Kim, ~~Seung Beom~~ Hong, ~~Hyun Kyu Song~~]]	+	[[Category: Kwon, D.H]]
		+	[[Category: Kim, B.-W]]
		+	[[Category: Kim, L]]
		+	[[Category: Song, H.K]]
		+	[[Category: Hong, S.B]]

OCA: Protected "5hzy" [edit=sysop:move=sysop]

OCA — Wed, 10 Feb 2016 15:59:28 GMT

Protected "5hzy" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:59, 10 February 2016

OCA: New page: '''Unreleased structure''' The entry 5hzy is ON HOLD Authors: Do Hoon Kwon, Leehyeon Kim, Byeong-Won Kim, Seung Beom Hong, Hyun Kyu Song Description: Crystal structure of the legionell...

OCA — Wed, 10 Feb 2016 15:59:27 GMT

New page: '''Unreleased structure''' The entry 5hzy is ON HOLD Authors: Do Hoon Kwon, Leehyeon Kim, Byeong-Won Kim, Seung Beom Hong, Hyun Kyu Song Description: Crystal structure of the legionell...

New page

'''Unreleased structure'''

The entry 5hzy is ON HOLD

Authors: Do Hoon Kwon, Leehyeon Kim, Byeong-Won Kim, Seung Beom Hong, Hyun Kyu Song

Description: Crystal structure of the legionella pneumophila effector protein RavZ -P6322
[[Category: Unreleased Structures]]
[[Category: Do Hoon Kwon, Leehyeon Kim, Byeong-Won Kim, Seung Beom Hong, Hyun Kyu Song]]