5ibw - Revision history

OCA at 13:45, 30 August 2023

OCA — Wed, 30 Aug 2023 13:45:00 GMT

←Older revision		Revision as of 13:45, 30 August 2023
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	<StructureSection load='5ibw' size='340' side='right'caption='[[5ibw]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='5ibw' size='340' side='right'caption='[[5ibw]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ibw]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Dicdi Dicdi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IBW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5IBW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ibw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IBW FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=NA:SODIUM+ION'>NA</scene~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~DDB_G0289563 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=44689 DICDI]), myoC, dmiC, DDB_G0276617 ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=44689 DICDI])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ibw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ibw OCA], [~~http~~://pdbe.org/5ibw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5ibw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5ibw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5ibw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ibw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ibw OCA], [https://pdbe.org/5ibw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ibw RCSB], [https://www.ebi.ac.uk/pdbsum/5ibw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ibw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~MYOC_DICDI MYOC_DICDI~~]~~] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Involved in the process of phagocytosis and appears to support streaming behavior.<ref>PMID:8609164</ref>~~	+	[https://www.uniprot.org/uniprot/Q54HC2_DICDI Q54HC2_DICDI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Dicdi~~]]	+	[[Category: Dictyostelium discoideum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Langelaan~~, D N~~]]	+	[[Category: Langelaan DN]]
-	[[Category: Smith~~, S P]]~~	+	[[Category: Smith SP]]
-	~~[[Category: Motor protein]]~~	+
-	~~[[Category: Myosin iq motif complex~~]]	+

OCA at 08:04, 8 January 2020

OCA — Wed, 08 Jan 2020 08:04:23 GMT

←Older revision		Revision as of 08:04, 8 January 2020
Line 1:		Line 1:

	==Complex of MlcC bound to the tandem IQ motif of MyoC==		==Complex of MlcC bound to the tandem IQ motif of MyoC==
-	<StructureSection load='5ibw' size='340' side='right' caption='[[5ibw]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='5ibw' size='340' side='right'caption='[[5ibw]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ibw]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IBW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IBW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ibw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dicdi Dicdi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IBW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IBW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DDB_G0289563 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=44689 DICDI]), myoC, dmiC, DDB_G0276617 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=44689 DICDI])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ibw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ibw OCA], [http://pdbe.org/5ibw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ibw RCSB], [http://www.ebi.ac.uk/pdbsum/5ibw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ibw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ibw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ibw OCA], [http://pdbe.org/5ibw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ibw RCSB], [http://www.ebi.ac.uk/pdbsum/5ibw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ibw ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:

	==See Also==		==See Also==
-	*[[Myosin\|Myosin]]	+	*[[Myosin 3D Structures\|Myosin 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Dicdi]]
		+	[[Category: Large Structures]]
	[[Category: Langelaan, D N]]		[[Category: Langelaan, D N]]
	[[Category: Smith, S P]]		[[Category: Smith, S P]]
	[[Category: Motor protein]]		[[Category: Motor protein]]
	[[Category: Myosin iq motif complex]]		[[Category: Myosin iq motif complex]]

OCA at 10:52, 13 September 2017

OCA — Wed, 13 Sep 2017 10:52:43 GMT

←Older revision		Revision as of 10:52, 13 September 2017
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 5ibw" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5ibw" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Myosin\|Myosin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:12, 10 August 2016

OCA — Wed, 10 Aug 2016 08:12:56 GMT

←Older revision		Revision as of 08:12, 10 August 2016
Line 9:		Line 9:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/MYOC_DICDI MYOC_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Involved in the process of phagocytosis and appears to support streaming behavior.<ref>PMID:8609164</ref>		[[http://www.uniprot.org/uniprot/MYOC_DICDI MYOC_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Involved in the process of phagocytosis and appears to support streaming behavior.<ref>PMID:8609164</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Myosin light chains are key regulators of class 1 myosins and typically comprise two domains, with calmodulin being the archetypal example. They bind IQ motifs within the myosin neck region and amplify conformational changes in motor domain. A single lobe light chain, myosin light chain C (MlcC), was recently identified and shown to specifically bind to two sequentially divergent IQ motifs of the Dictyostelium myosin-1C. Towards providing a molecular basis of this interaction, the structures of apo-MlcC and a 2:1 MlcC:myosin-1C neck complex were determined. The two non-functional EF-hand motifs of MlcC pack together to form a globular four-helix bundle that opens up to expose a central hydrophobic groove, which interacts the N-terminal portion of the divergent IQ1 and IQ2 motifs. N- and C-terminal regions of MlcC make critical contacts that contribute to its specific interactions with the myosin-1C divergent IQ motifs; contacts that deviate from the traditional mode of calmodulin-IQ recognition.
		+
		+	Structure of the single-lobe myosin light chain C in complex with the light chain-binding domains of myosin-1C provides insights into divergent IQ-motif recognition.,Langelaan DN, Liburd J, Yang Y, Miller E, Chitayat S, Crawley SW, Cote GP, Smith SP J Biol Chem. 2016 Jul 27. pii: jbc.M116.746313. PMID:27466369<ref>PMID:27466369</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5ibw" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 04:16, 4 August 2016

OCA — Thu, 04 Aug 2016 04:16:27 GMT

←Older revision		Revision as of 04:16, 4 August 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5ibw is ~~ON HOLD~~ ~~until Paper Publication~~	+	==Complex of MlcC bound to the tandem IQ motif of MyoC==
-		+	<StructureSection load='5ibw' size='340' side='right' caption='[[5ibw]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5ibw]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IBW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IBW FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ibw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ibw OCA], [http://pdbe.org/5ibw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ibw RCSB], [http://www.ebi.ac.uk/pdbsum/5ibw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ibw ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MYOC_DICDI MYOC_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Involved in the process of phagocytosis and appears to support streaming behavior.<ref>PMID:8609164</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Langelaan, D N]]
		+	[[Category: Smith, S P]]
		+	[[Category: Motor protein]]
		+	[[Category: Myosin iq motif complex]]

OCA at 14:18, 15 May 2016

OCA — Sun, 15 May 2016 14:18:46 GMT

←Older revision		Revision as of 14:18, 15 May 2016
Line 3:		Line 3:
	The entry 5ibw is ON HOLD until Paper Publication		The entry 5ibw is ON HOLD until Paper Publication

-	Authors: ~~Langelaan, D.N., Smith, S.P.~~	+	Authors:

	Description:		Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Langelaan, D.N]]
-	[[Category: Smith, S.P]]

OCA: Protected "5ibw" [edit=sysop:move=sysop]

OCA — Wed, 02 Mar 2016 13:42:08 GMT

Protected "5ibw" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:42, 2 March 2016

OCA: New page: '''Unreleased structure''' The entry 5ibw is ON HOLD until Paper Publication Authors: Langelaan, D.N., Smith, S.P. Description: Category: Unreleased Structures [[Category: Langela...

OCA — Wed, 02 Mar 2016 13:42:06 GMT

New page: '''Unreleased structure''' The entry 5ibw is ON HOLD until Paper Publication Authors: Langelaan, D.N., Smith, S.P. Description: Category: Unreleased Structures [[Category: Langela...

New page

'''Unreleased structure'''

The entry 5ibw is ON HOLD until Paper Publication

Authors: Langelaan, D.N., Smith, S.P.

Description:
[[Category: Unreleased Structures]]
[[Category: Langelaan, D.N]]
[[Category: Smith, S.P]]