5io5 - Revision history

OCA at 14:03, 30 August 2023

OCA — Wed, 30 Aug 2023 14:03:14 GMT

←Older revision		Revision as of 14:03, 30 August 2023
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	<StructureSection load='5io5' size='340' side='right'caption='[[5io5]], [[Resolution\|resolution]] 2.85Å' scene=''>		<StructureSection load='5io5' size='340' side='right'caption='[[5io5]], [[Resolution\|resolution]] 2.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5io5]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IO5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5IO5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5io5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IO5 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.85Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[3npo\|3npo]], [[5io6\|5io6]], [[5io7\|5io7]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5io5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5io5 OCA], [~~http~~://pdbe.org/5io5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5io5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5io5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5io5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5io5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5io5 OCA], [https://pdbe.org/5io5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5io5 RCSB], [https://www.ebi.ac.uk/pdbsum/5io5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5io5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/LACB_BOVIN LACB_BOVIN]] Primary component of whey, it binds retinol and is probably involved in the transport of that molecule.	+	[https://www.uniprot.org/uniprot/LACB_BOVIN LACB_BOVIN] Primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Biela, A]]	+	[[Category: Biela A]]
-	[[Category: Kurpiewska, K]]	+	[[Category: Kurpiewska K]]
-	~~[[Category: Beta-lactoglobulin]]~~	+
-	~~[[Category: Lipocalin]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 07:25, 3 June 2020

OCA — Wed, 03 Jun 2020 07:25:24 GMT

←Older revision		Revision as of 07:25, 3 June 2020
Line 1:		Line 1:

	==Unliganded form of bovine beta-lactoglobulin, ambient pressure==		==Unliganded form of bovine beta-lactoglobulin, ambient pressure==
-	<StructureSection load='5io5' size='340' side='right' caption='[[5io5]], [[Resolution\|resolution]] 2.85Å' scene=''>	+	<StructureSection load='5io5' size='340' side='right'caption='[[5io5]], [[Resolution\|resolution]] 2.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5io5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IO5 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5IO5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5io5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IO5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IO5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3npo\|3npo]], [[5io6\|5io6]], [[5io7\|5io7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3npo\|3npo]], [[5io6\|5io6]], [[5io7\|5io7]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5io5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5io5 OCA], [http://pdbe.org/5io5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5io5 RCSB], [http://www.ebi.ac.uk/pdbsum/5io5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5io5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5io5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5io5 OCA], [http://pdbe.org/5io5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5io5 RCSB], [http://www.ebi.ac.uk/pdbsum/5io5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5io5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 5io5" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5io5" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Beta-lactoglobulin 3D structures\|Beta-lactoglobulin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
		+	[[Category: Large Structures]]
	[[Category: Biela, A]]		[[Category: Biela, A]]
	[[Category: Kurpiewska, K]]		[[Category: Kurpiewska, K]]

OCA at 10:08, 15 November 2017

OCA — Wed, 15 Nov 2017 10:08:18 GMT

←Older revision		Revision as of 10:08, 15 November 2017
Line 6:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3npo\|3npo]], [[5io6\|5io6]], [[5io7\|5io7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3npo\|3npo]], [[5io6\|5io6]], [[5io7\|5io7]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5io5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5io5 OCA], [http://pdbe.org/5io5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5io5 RCSB], [http://www.ebi.ac.uk/pdbsum/5io5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5io5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5io5 OCA], [http://pdbe.org/5io5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5io5 RCSB], [http://www.ebi.ac.uk/pdbsum/5io5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5io5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/LACB_BOVIN LACB_BOVIN]] Primary component of whey, it binds retinol and is probably involved in the transport of that molecule.		[[http://www.uniprot.org/uniprot/LACB_BOVIN LACB_BOVIN]] Primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	beta-Lactoglobulin, being one of the principal whey protein, is of huge importance to the food industry. Temperature/pressure effects on this small protein has been extensively studied by industry. To characterize biochemical properties of beta-lactoglobulin after or during pressurization, a wide range of methods have been used thus far. In this study, for the first time, the pressure-induced conformation of beta-lactoglobulin in the crystal state was determined, at pressure 430 MPa. Changes observed in the high pressure structure correlate with the physico-chemical properties of pressure-treated beta-lactoglobulin obtained from dynamic light scattering, electrophoretic mobility and quartz crystal microbalance with dissipation monitoring measurements. A comparison between the beta-lactoglobulin structures determined at both high and ambient pressure contrasts the stable nature of the protein core and adjacent loop fragments. At high pressure the beta-lactoglobulin structure presents early signs of dimer dissociation, charge and conformational changes characteristic for initial unfolded intermediate as well as a significant modification of the binding pocket volume. Those observations are supported by changes in zeta potential values and results in increase affinity of the beta-lactoglobulin adsorption onto gold surface. Observed pressure-induced structural modifications were previously suggested as an important factor contributing to beta-lactoglobulin denaturation process. Presented studies provide detailed analysis of pressure-associated structural changes influencing beta-lactoglobulin conformation and consequently its adsorption.
		+
		+	Investigation of high pressure effect on the structure and adsorption of beta-lactoglobulin.,Kurpiewska K, Biela A, Loch JI, Swiatek S, Jachimska B, Lewinski K Colloids Surf B Biointerfaces. 2017 Oct 31;161:387-393. doi:, 10.1016/j.colsurfb.2017.10.069. PMID:29112912<ref>PMID:29112912</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5io5" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA: Protected "5io5" [edit=sysop:move=sysop]

OCA — Wed, 11 May 2016 03:54:19 GMT

Protected "5io5" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:54, 11 May 2016

OCA: New page: ==Unliganded form of bovine beta-lactoglobulin, ambient pressure==
OCA — Wed, 11 May 2016 03:54:16 GMT

New page: ==Unliganded form of bovine beta-lactoglobulin, ambient pressure== <StructureSection load='5io5' size='340' side='right' caption='5io5, resolution 2.85Å' scene=''...

New page

==Unliganded form of bovine beta-lactoglobulin, ambient pressure==
<StructureSection load='5io5' size='340' side='right' caption='[[5io5]], [[Resolution|resolution]] 2.85Å' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5io5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IO5 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IO5 FirstGlance]. 
</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[3npo|3npo]], [[5io6|5io6]], [[5io7|5io7]]</td></tr>
<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5io5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5io5 OCA], [http://pdbe.org/5io5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5io5 RCSB], [http://www.ebi.ac.uk/pdbsum/5io5 PDBsum]</td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/LACB_BOVIN LACB_BOVIN]] Primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
TOC
</StructureSection>
[[Category: Bos taurus]]
[[Category: Biela, A]]
[[Category: Kurpiewska, K]]
[[Category: Beta-lactoglobulin]]
[[Category: Lipocalin]]
[[Category: Transport protein]]