5iuq - Revision history

OCA at 10:32, 6 September 2023

OCA — Wed, 06 Sep 2023 10:32:12 GMT

←Older revision		Revision as of 10:32, 6 September 2023
Line 1:		Line 1:

	==Galectin-3c in complex with Bisamido-thiogalactoside derivative 4==		==Galectin-3c in complex with Bisamido-thiogalactoside derivative 4==
-	<StructureSection load='5iuq' size='340' side='right' caption='[[5iuq]], [[Resolution\|resolution]] 1.12Å' scene=''>	+	<StructureSection load='5iuq' size='340' side='right'caption='[[5iuq]], [[Resolution\|resolution]] 1.12Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5iuq]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IUQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5IUQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5iuq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IUQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6E1:3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-BETA-D-GALACTOPYRANOSYL+3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-1-THIO-BETA-D-GALACTOPYRANOSIDE'>6E1</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.121Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4blj\|4blj]], [[4bli\|4bli]], [[4bm8\|4bm8]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6E1:3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-BETA-D-GALACTOPYRANOSYL+3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-1-THIO-BETA-D-GALACTOPYRANOSIDE'>6E1</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LGALS3, MAC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iuq OCA], [https://pdbe.org/5iuq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iuq RCSB], [https://www.ebi.ac.uk/pdbsum/5iuq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iuq ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5iuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iuq OCA], [~~http~~://pdbe.org/5iuq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5iuq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5iuq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5iuq ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/LEG3_HUMAN LEG3_HUMAN]] Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.<ref>PMID:15181153</ref> <ref>PMID:19594635</ref> <ref>PMID:19616076</ref>	+	[https://www.uniprot.org/uniprot/LEG3_HUMAN LEG3_HUMAN] Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.<ref>PMID:15181153</ref> <ref>PMID:19594635</ref> <ref>PMID:19616076</ref>
		+
		+	==See Also==
		+	*[[Galectin 3D structures\|Galectin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: Aurelius, O]]	+	[[Category: Large Structures]]
-	[[Category: Engstrom, O]]	+	[[Category: Aurelius O]]
-	[[Category: Hakansson, M]]	+	[[Category: Engstrom O]]
-	[[Category: Leffler, H]]	+	[[Category: Hakansson M]]
-	[[Category: Logan~~, D T~~]]	+	[[Category: Leffler H]]
-	[[Category: Nilsson~~, U J~~]]	+	[[Category: Logan DT]]
-	[[Category: Noresson, A L]]	+	[[Category: Nilsson UJ]]
-	[[Category: Oberg~~, C T~~]]	+	[[Category: Noresson A-L]]
-	[[Category: Sundin~~, A P]]~~	+	[[Category: Oberg CT]]
-	~~[[Category: Crd]]~~	+	[[Category: Sundin AP]]
-	~~[[Category: Gal3c]]~~	+
-	~~[[Category: Sugar binding protein~~]]	+

OCA at 08:07, 17 January 2018

OCA — Wed, 17 Jan 2018 08:07:09 GMT

←Older revision		Revision as of 08:07, 17 January 2018
Line 3:		Line 3:
	<StructureSection load='5iuq' size='340' side='right' caption='[[5iuq]], [[Resolution\|resolution]] 1.12Å' scene=''>		<StructureSection load='5iuq' size='340' side='right' caption='[[5iuq]], [[Resolution\|resolution]] 1.12Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5iuq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IUQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5iuq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IUQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6E1:3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-BETA-D-GALACTOPYRANOSYL+3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-1-THIO-BETA-D-GALACTOPYRANOSIDE'>6E1</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6E1:3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-BETA-D-GALACTOPYRANOSYL+3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-1-THIO-BETA-D-GALACTOPYRANOSIDE'>6E1</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4blj\|4blj]], [[4bli\|4bli]], [[4bm8\|4bm8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4blj\|4blj]], [[4bli\|4bli]], [[4bm8\|4bm8]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LGALS3, MAC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iuq OCA], [http://pdbe.org/5iuq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iuq RCSB], [http://www.ebi.ac.uk/pdbsum/5iuq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iuq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iuq OCA], [http://pdbe.org/5iuq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iuq RCSB], [http://www.ebi.ac.uk/pdbsum/5iuq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iuq ProSAT]</span></td></tr>
	</table>		</table>
Line 14:		Line 15:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Aurelius, O]]		[[Category: Aurelius, O]]
	[[Category: Engstrom, O]]		[[Category: Engstrom, O]]

OCA at 13:44, 29 March 2017

OCA — Wed, 29 Mar 2017 13:44:12 GMT

←Older revision		Revision as of 13:44, 29 March 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5iuq ~~is ON HOLD until Paper Publication~~	+	==Galectin-3c in complex with Bisamido-thiogalactoside derivative 4==
-		+	<StructureSection load='5iuq' size='340' side='right' caption='[[5iuq]], [[Resolution\|resolution]] 1.12Å' scene=''>
-	~~Authors~~: ~~Noresson, A~~.-L., ~~Aurelius~~, O., ~~Oberg~~, ~~C.T.~~, ~~Engstrom~~, O., ~~Sundin~~, A.P., ~~Hakansson~~, M., ~~Logan, D~~.T., ~~Leffler, H~~., ~~Nilsson, U~~.J.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5iuq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IUQ FirstGlance]. <br>
-	~~Description: Galectin-3c in complex with Bisamido-thiogalactoside derivative 4~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6E1:3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-BETA-D-GALACTOPYRANOSYL+3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-1-THIO-BETA-D-GALACTOPYRANOSIDE'>6E1</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4blj\|4blj]], [[4bli\|4bli]], [[4bm8\|4bm8]]</td></tr>
-	[[Category: ~~Logan~~, ~~D.T~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iuq OCA], [http://pdbe.org/5iuq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iuq RCSB], [http://www.ebi.ac.uk/pdbsum/5iuq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iuq ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LEG3_HUMAN LEG3_HUMAN]] Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.<ref>PMID:15181153</ref> <ref>PMID:19594635</ref> <ref>PMID:19616076</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Aurelius, O]]
	[[Category: Engstrom, O]]		[[Category: Engstrom, O]]
		+	[[Category: Hakansson, M]]
	[[Category: Leffler, H]]		[[Category: Leffler, H]]
-	[[Category: ~~Sundin~~, ~~A.P~~]]	+	[[Category: Logan, D T]]
-	[[Category: Noresson, A.-L]]	+	[[Category: Nilsson, U J]]
-	[[Category: Oberg, C.T]]	+	[[Category: Noresson, A L]]
-	[[Category: ~~Nilsson~~, ~~U.J~~]]	+	[[Category: Oberg, C T]]
-	[[Category: ~~Hakansson, M~~]]	+	[[Category: Sundin, A P]]
-	[[Category: ~~Aurelius, O~~]]	+	[[Category: Crd]]
		+	[[Category: Gal3c]]
		+	[[Category: Sugar binding protein]]

OCA at 09:41, 9 March 2017

OCA — Thu, 09 Mar 2017 09:41:04 GMT

←Older revision		Revision as of 09:41, 9 March 2017
Line 7:		Line 7:
	Description: Galectin-3c in complex with Bisamido-thiogalactoside derivative 4		Description: Galectin-3c in complex with Bisamido-thiogalactoside derivative 4
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Sundin, A.P]]
-	[[Category: Oberg, C.T]]
-	[[Category: Hakansson, M]]
	[[Category: Logan, D.T]]		[[Category: Logan, D.T]]
	[[Category: Engstrom, O]]		[[Category: Engstrom, O]]
	[[Category: Leffler, H]]		[[Category: Leffler, H]]
		+	[[Category: Sundin, A.P]]
	[[Category: Noresson, A.-L]]		[[Category: Noresson, A.-L]]
		+	[[Category: Oberg, C.T]]
	[[Category: Nilsson, U.J]]		[[Category: Nilsson, U.J]]
		+	[[Category: Hakansson, M]]
	[[Category: Aurelius, O]]		[[Category: Aurelius, O]]

OCA: Protected "5iuq" [edit=sysop:move=sysop]

OCA — Wed, 11 May 2016 00:58:50 GMT

Protected "5iuq" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:58, 11 May 2016

OCA: New page: '''Unreleased structure''' The entry 5iuq is ON HOLD until Paper Publication Authors: Noresson, A.-L., Aurelius, O., Oberg, C.T., Engstrom, O., Sundin, A.P., Hakansson, M., Logan, D.T.,...

OCA — Wed, 11 May 2016 00:58:48 GMT

New page: '''Unreleased structure''' The entry 5iuq is ON HOLD until Paper Publication Authors: Noresson, A.-L., Aurelius, O., Oberg, C.T., Engstrom, O., Sundin, A.P., Hakansson, M., Logan, D.T.,...

New page

'''Unreleased structure'''

The entry 5iuq is ON HOLD until Paper Publication

Authors: Noresson, A.-L., Aurelius, O., Oberg, C.T., Engstrom, O., Sundin, A.P., Hakansson, M., Logan, D.T., Leffler, H., Nilsson, U.J.

Description: Galectin-3c in complex with Bisamido-thiogalactoside derivative 4
[[Category: Unreleased Structures]]
[[Category: Sundin, A.P]]
[[Category: Oberg, C.T]]
[[Category: Hakansson, M]]
[[Category: Logan, D.T]]
[[Category: Engstrom, O]]
[[Category: Leffler, H]]
[[Category: Noresson, A.-L]]
[[Category: Nilsson, U.J]]
[[Category: Aurelius, O]]