5j4g - Revision history

OCA at 10:48, 6 September 2023

OCA — Wed, 06 Sep 2023 10:48:05 GMT

←Older revision		Revision as of 10:48, 6 September 2023
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	<StructureSection load='5j4g' size='340' side='right'caption='[[5j4g]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='5j4g' size='340' side='right'caption='[[5j4g]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5j4g]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Campylobacter_pylori Campylobacter~~ pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J4G OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5J4G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5j4g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J4G FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[5j4f\|5j4f]]</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">HP_0902 ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=85962 Campylobacter pylori])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j4g OCA], [https://pdbe.org/5j4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j4g RCSB], [https://www.ebi.ac.uk/pdbsum/5j4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j4g ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5j4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j4g OCA], [~~http~~://pdbe.org/5j4g PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5j4g RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5j4g PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5j4g ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/O25562_HELPY O25562_HELPY]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Campylobacter~~ pylori]]	+	[[Category: Helicobacter pylori 26695]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kim~~, H Y~~]]	+	[[Category: Kim HY]]
-	[[Category: Kim~~, J H~~]]	+	[[Category: Kim JH]]
-	[[Category: Lee~~, W C~~]]	+	[[Category: Lee WC]]
-	[[Category: Sim~~, D W~~]]	+	[[Category: Sim DW]]
-	[[Category: Won~~, H S]]~~	+	[[Category: Won HS]]
-	~~[[Category: Cupin family]]~~	+
-	~~[[Category: Helicobacter pylori]]~~	+
-	~~[[Category: Hp0902]]~~	+
-	~~[[Category: Secretory protein]]~~	+
-	~~[[Category: Uncharacterized protein]]~~	+
-	~~[[Category: Unknown function~~]]	+

OCA at 07:17, 19 February 2020

OCA — Wed, 19 Feb 2020 07:17:57 GMT

←Older revision		Revision as of 07:17, 19 February 2020
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	==Crystal structure of the C-terminally His6-tagged HP0902, an uncharacterized protein from Helicobacter pylori 26695==		==Crystal structure of the C-terminally His6-tagged HP0902, an uncharacterized protein from Helicobacter pylori 26695==
-	<StructureSection load='5j4g' size='340' side='right' caption='[[5j4g]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='5j4g' size='340' side='right'caption='[[5j4g]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5j4g]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J4G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J4G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5j4g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J4G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J4G FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5j4f\|5j4f]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5j4f\|5j4f]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HP_0902 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85962 Campylobacter pylori])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j4g OCA], [http://pdbe.org/5j4g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j4g RCSB], [http://www.ebi.ac.uk/pdbsum/5j4g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j4g ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j4g OCA], [http://pdbe.org/5j4g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j4g RCSB], [http://www.ebi.ac.uk/pdbsum/5j4g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j4g ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Campylobacter pylori]]
		+	[[Category: Large Structures]]
	[[Category: Kim, H Y]]		[[Category: Kim, H Y]]
	[[Category: Kim, J H]]		[[Category: Kim, J H]]

OCA at 09:24, 10 March 2017

OCA — Fri, 10 Mar 2017 09:24:55 GMT

←Older revision		Revision as of 09:24, 10 March 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5j4g is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of the C-terminally His6-tagged HP0902, an uncharacterized protein from Helicobacter pylori 26695==
		+	<StructureSection load='5j4g' size='340' side='right' caption='[[5j4g]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5j4g]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J4G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J4G FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5j4f\|5j4f]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j4g OCA], [http://pdbe.org/5j4g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j4g RCSB], [http://www.ebi.ac.uk/pdbsum/5j4g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j4g ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We solved the crystal structure of a functionally uncharacterized protein, HP0902, from Helicobacter pylori. Its structure demonstrated an all-beta cupin fold that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. In contrast, isothermal titration calorimetry and NMR titration demonstrated that HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins. This report constitutes the first identification of an LPS-interacting protein, both in the cupin family and in H. pylori. Furthermore, identification of the ability of HP0902 to bind LPS uncovers a putative role for this protein in H. pylori pathogenicity.

-	~~Authors~~:	+	Structural identification of the lipopolysaccharide-binding capability of a cupin-family protein from Helicobacter pylori.,Sim DW, Kim JH, Kim HY, Jang JH, Lee WC, Kim EH, Park PJ, Lee KH, Won HS FEBS Lett. 2016 Sep;590(17):2997-3004. doi: 10.1002/1873-3468.12332. Epub 2016, Aug 11. PMID:27466800<ref>PMID:27466800</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5j4g" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Kim, H Y]]
		+	[[Category: Kim, J H]]
		+	[[Category: Lee, W C]]
		+	[[Category: Sim, D W]]
		+	[[Category: Won, H S]]
		+	[[Category: Cupin family]]
		+	[[Category: Helicobacter pylori]]
		+	[[Category: Hp0902]]
		+	[[Category: Secretory protein]]
		+	[[Category: Uncharacterized protein]]
		+	[[Category: Unknown function]]

OCA at 15:02, 15 May 2016

OCA — Sun, 15 May 2016 15:02:28 GMT

←Older revision		Revision as of 15:02, 15 May 2016
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	The entry 5j4g is ON HOLD until Paper Publication		The entry 5j4g is ON HOLD until Paper Publication

-	Authors: ~~Sim, D.W., Lee, W.C., Kim, H.Y., Kim, J.H., Won, H.S.~~	+	Authors:

	Description:		Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Kim, J.H]]
-	[[Category: Kim, H.Y]]
-	[[Category: Sim, D.W]]
-	[[Category: Lee, W.C]]
-	[[Category: Won, H.S]]

OCA: Protected "5j4g" [edit=sysop:move=sysop]

OCA — Wed, 11 May 2016 01:26:42 GMT

Protected "5j4g" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:26, 11 May 2016

OCA: New page: '''Unreleased structure''' The entry 5j4g is ON HOLD until Paper Publication Authors: Sim, D.W., Lee, W.C., Kim, H.Y., Kim, J.H., Won, H.S. Description: [[Category: Unreleased Structu...

OCA — Wed, 11 May 2016 01:26:41 GMT

New page: '''Unreleased structure''' The entry 5j4g is ON HOLD until Paper Publication Authors: Sim, D.W., Lee, W.C., Kim, H.Y., Kim, J.H., Won, H.S. Description: [[Category: Unreleased Structu...

New page

'''Unreleased structure'''

The entry 5j4g is ON HOLD until Paper Publication

Authors: Sim, D.W., Lee, W.C., Kim, H.Y., Kim, J.H., Won, H.S.

Description:
[[Category: Unreleased Structures]]
[[Category: Kim, J.H]]
[[Category: Kim, H.Y]]
[[Category: Sim, D.W]]
[[Category: Lee, W.C]]
[[Category: Won, H.S]]