5jhf - Revision history

OCA at 18:52, 20 September 2023

OCA — Wed, 20 Sep 2023 18:52:14 GMT

←Older revision		Revision as of 18:52, 20 September 2023
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	<StructureSection load='5jhf' size='340' side='right'caption='[[5jhf]], [[Resolution\|resolution]] 3.21Å' scene=''>		<StructureSection load='5jhf' size='340' side='right'caption='[[5jhf]], [[Resolution\|resolution]] 3.21Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5jhf]] is a 10 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_56472 Atcc 56472~~] and [~~http~~://en.wikipedia.org/wiki/~~Kluyveromyces_thermotolerans Kluyveromyces~~ thermotolerans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JHF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5JHF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5jhf]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Lachancea_thermotolerans Lachancea thermotolerans] and [https://en.wikipedia.org/wiki/Lachancea_thermotolerans_CBS_6340 Lachancea thermotolerans CBS 6340]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JHF FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>KLTH0D11660g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~559295 Kluyveromyces thermotolerans])~~, ~~KLTH0C07942g (~~[~~http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559295 Kluyveromyces thermotolerans~~]~~), KLTH0D15642g ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=559295 Kluyveromyces thermotolerans])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.21Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5jhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jhf OCA], [~~http~~://pdbe.org/5jhf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5jhf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5jhf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5jhf ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jhf OCA], [https://pdbe.org/5jhf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jhf RCSB], [https://www.ebi.ac.uk/pdbsum/5jhf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jhf ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/C5DEB9_LACTC C5DEB9_LACTC]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 56472~~]]	+	[[Category: Lachancea thermotolerans]]
-	[[Category: ~~Kluyveromyces~~ thermotolerans]]	+	[[Category: Lachancea thermotolerans CBS 6340]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fujioka, Y]]	+	[[Category: Fujioka Y]]
-	[[Category: Noda~~, N N]]~~	+	[[Category: Noda NN]]
-	~~[[Category: Coiled-coil]]~~	+
-	~~[[Category: Protein transport~~]]	+

OCA at 07:19, 19 February 2020

OCA — Wed, 19 Feb 2020 07:19:01 GMT

←Older revision		Revision as of 07:19, 19 February 2020
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	==Crystal structure of Atg13(17BR)-Atg13(17LR)-Atg17-Atg29-Atg31 complex==		==Crystal structure of Atg13(17BR)-Atg13(17LR)-Atg17-Atg29-Atg31 complex==
-	<StructureSection load='5jhf' size='340' side='right' caption='[[5jhf]], [[Resolution\|resolution]] 3.21Å' scene=''>	+	<StructureSection load='5jhf' size='340' side='right'caption='[[5jhf]], [[Resolution\|resolution]] 3.21Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5jhf]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JHF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5jhf]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_56472 Atcc 56472] and [http://en.wikipedia.org/wiki/Kluyveromyces_thermotolerans Kluyveromyces thermotolerans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JHF FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jhf OCA], [http://pdbe.org/5jhf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jhf RCSB], [http://www.ebi.ac.uk/pdbsum/5jhf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jhf ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLTH0D11660g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559295 Kluyveromyces thermotolerans]), KLTH0C07942g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559295 Kluyveromyces thermotolerans]), KLTH0D15642g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559295 Kluyveromyces thermotolerans])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jhf OCA], [http://pdbe.org/5jhf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jhf RCSB], [http://www.ebi.ac.uk/pdbsum/5jhf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jhf ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 56472]]
		+	[[Category: Kluyveromyces thermotolerans]]
		+	[[Category: Large Structures]]
	[[Category: Fujioka, Y]]		[[Category: Fujioka, Y]]
	[[Category: Noda, N N]]		[[Category: Noda, N N]]
	[[Category: Coiled-coil]]		[[Category: Coiled-coil]]
	[[Category: Protein transport]]		[[Category: Protein transport]]

OCA at 04:02, 4 August 2016

OCA — Thu, 04 Aug 2016 04:02:30 GMT

←Older revision		Revision as of 04:02, 4 August 2016
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-	'''Unreleased structure'''

-	~~The entry~~ 5jhf is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of Atg13(17BR)-Atg13(17LR)-Atg17-Atg29-Atg31 complex==
		+	<StructureSection load='5jhf' size='340' side='right' caption='[[5jhf]], [[Resolution\|resolution]] 3.21Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5jhf]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JHF FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jhf OCA], [http://pdbe.org/5jhf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jhf RCSB], [http://www.ebi.ac.uk/pdbsum/5jhf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jhf ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Autophagosome formation in yeast entails starvation-induced assembly of the pre-autophagosomal structure (PAS), in which multiple Atg1 complexes (composed of Atg1, Atg13, and the Atg17-Atg29-Atg31 subcomplex) are initially engaged. However, the molecular mechanisms underlying the multimeric assembly of these complexes remain unclear. Using structural and biological techniques, we herein demonstrate that Atg13 has a large intrinsically disordered region (IDR) and interacts with two distinct Atg17 molecules using two binding regions in the IDR. We further reveal that these two binding regions are essential not only for Atg1 complex assembly in vitro, but also for PAS organization in vivo. These findings underscore the structural and functional significance of the IDR of Atg13 in autophagy initiation: Atg13 provides intercomplex linkages between Atg17-Atg29-Atg31 complexes, thereby leading to supramolecular self-assembly of Atg1 complexes, in turn accelerating the initial events of autophagy, including autophosphorylation of Atg1, recruitment of Atg9 vesicles, and phosphorylation of Atg9 by Atg1.

-	~~Authors~~:	+	The Intrinsically Disordered Protein Atg13 Mediates Supramolecular Assembly of Autophagy Initiation Complexes.,Yamamoto H, Fujioka Y, Suzuki SW, Noshiro D, Suzuki H, Kondo-Kakuta C, Kimura Y, Hirano H, Ando T, Noda NN, Ohsumi Y Dev Cell. 2016 Jul 11;38(1):86-99. doi: 10.1016/j.devcel.2016.06.015. PMID:27404361<ref>PMID:27404361</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5jhf" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Fujioka, Y]]
		+	[[Category: Noda, N N]]
		+	[[Category: Coiled-coil]]
		+	[[Category: Protein transport]]

OCA at 15:25, 15 May 2016

OCA — Sun, 15 May 2016 15:25:28 GMT

←Older revision		Revision as of 15:25, 15 May 2016
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5jhf is ON HOLD	+	The entry 5jhf is ON HOLD until Paper Publication

-	Authors: ~~Fujioka, Y., Noda, N.N.~~	+	Authors:

	Description:		Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Fujioka, Y]]
-	[[Category: Noda, N.N]]

OCA: Protected "5jhf" [edit=sysop:move=sysop]

OCA — Wed, 11 May 2016 02:04:31 GMT

Protected "5jhf" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:04, 11 May 2016

OCA: New page: '''Unreleased structure''' The entry 5jhf is ON HOLD Authors: Fujioka, Y., Noda, N.N. Description: Category: Unreleased Structures Category: Fujioka, Y Category: Noda, N.N

OCA — Wed, 11 May 2016 02:04:30 GMT

New page: '''Unreleased structure''' The entry 5jhf is ON HOLD Authors: Fujioka, Y., Noda, N.N. Description: Category: Unreleased Structures Category: Fujioka, Y Category: Noda, N.N

New page

'''Unreleased structure'''

The entry 5jhf is ON HOLD

Authors: Fujioka, Y., Noda, N.N.

Description:
[[Category: Unreleased Structures]]
[[Category: Fujioka, Y]]
[[Category: Noda, N.N]]