5jje - Revision history

OCA at 18:55, 20 September 2023

OCA — Wed, 20 Sep 2023 18:55:01 GMT

←Older revision		Revision as of 18:55, 20 September 2023
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	<StructureSection load='5jje' size='340' side='right'caption='[[5jje]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='5jje' size='340' side='right'caption='[[5jje]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5jje]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JJE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5JJE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5jje]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Natronomonas_pharaonis Natronomonas pharaonis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JJE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=LFA:EICOSANE'>LFA</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5jje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jje OCA], [~~http~~://pdbe.org/5jje PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5jje RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5jje PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5jje ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=LFA:EICOSANE'>LFA</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jje OCA], [https://pdbe.org/5jje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jje RCSB], [https://www.ebi.ac.uk/pdbsum/5jje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jje ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/BACS2_NATPH BACS2_NATPH]] Involved in the control of phototaxis. Seems to activate a methyl-accepting protein (HTR-II). Photoreceptor for blue light. [[http://www.uniprot.org/uniprot/HTR2_NATPH HTR2_NATPH]] Transduces signals from the phototaxis receptor sensory rhodopsin II (SR-II) to the flagellar motor. Responds to light changes through the variation of the level of methylation. Also acts as a chemotransducer.	+	[https://www.uniprot.org/uniprot/BACS2_NATPH BACS2_NATPH] Involved in the control of phototaxis. Seems to activate a methyl-accepting protein (HTR-II). Photoreceptor for blue light.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Balandin, T]]	+	[[Category: Natronomonas pharaonis]]
-	[[Category: Borshchevskiy, V]]	+	[[Category: Balandin T]]
-	[[Category: Bueldt, G]]	+	[[Category: Borshchevskiy V]]
-	[[Category: Engelhard, M]]	+	[[Category: Bueldt G]]
-	[[Category: Gordeliy, V]]	+	[[Category: Engelhard M]]
-	[[Category: Grudinin, S]]	+	[[Category: Gordeliy V]]
-	[[Category: Gushchin, I]]	+	[[Category: Grudinin S]]
-	[[Category: Ishchenko, A]]	+	[[Category: Gushchin I]]
-	[[Category: Klare, J]]	+	[[Category: Ishchenko A]]
-	[[Category: Polovinkin, V]]	+	[[Category: Klare J]]
-	[[Category: Remeeva, A]]	+	[[Category: Polovinkin V]]
-	[[Category: Round, E]]	+	[[Category: Remeeva A]]
-	[[Category: Utrobin, P]]	+	[[Category: Round E]]
-	~~[[Category: Membrane protein complex]]~~	+	[[Category: Utrobin P]]
-	~~[[Category: Sensory rhodopsin ii]]~~	+
-	~~[[Category: Signaling protein]]~~	+
-	~~[[Category: Transducer~~]]	+

OCA at 07:52, 10 June 2020

OCA — Wed, 10 Jun 2020 07:52:10 GMT

←Older revision		Revision as of 07:52, 10 June 2020
Line 1:		Line 1:

	==Structure of the SRII/HtrII Complex in I212121 space group ("U" shape)==		==Structure of the SRII/HtrII Complex in I212121 space group ("U" shape)==
-	<StructureSection load='5jje' size='340' side='right' caption='[[5jje]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='5jje' size='340' side='right'caption='[[5jje]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5jje]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JJE OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5JJE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5jje]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JJE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JJE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=LFA:EICOSANE'>LFA</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=LFA:EICOSANE'>LFA</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5jje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jje OCA], [http://pdbe.org/5jje PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jje RCSB], [http://www.ebi.ac.uk/pdbsum/5jje PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jje ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jje OCA], [http://pdbe.org/5jje PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jje RCSB], [http://www.ebi.ac.uk/pdbsum/5jje PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jje ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</div>		</div>
	<div class="pdbe-citations 5jje" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5jje" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Bacteriorhodopsin 3D structures\|Bacteriorhodopsin 3D structures]]
		+	*[[Rhodopsin 3D structures\|Rhodopsin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Balandin, T]]		[[Category: Balandin, T]]
	[[Category: Borshchevskiy, V]]		[[Category: Borshchevskiy, V]]

OCA at 17:40, 10 March 2017

OCA — Fri, 10 Mar 2017 17:40:13 GMT

←Older revision		Revision as of 17:40, 10 March 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5jje is ~~ON HOLD until Paper~~ Publication	+	==Structure of the SRII/HtrII Complex in I212121 space group ("U" shape)==
		+	<StructureSection load='5jje' size='340' side='right' caption='[[5jje]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5jje]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JJE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JJE FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=LFA:EICOSANE'>LFA</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jje OCA], [http://pdbe.org/5jje PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jje RCSB], [http://www.ebi.ac.uk/pdbsum/5jje PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jje ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BACS2_NATPH BACS2_NATPH]] Involved in the control of phototaxis. Seems to activate a methyl-accepting protein (HTR-II). Photoreceptor for blue light. [[http://www.uniprot.org/uniprot/HTR2_NATPH HTR2_NATPH]] Transduces signals from the phototaxis receptor sensory rhodopsin II (SR-II) to the flagellar motor. Responds to light changes through the variation of the level of methylation. Also acts as a chemotransducer.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The complex of two membrane proteins, sensory rhodopsin II (NpSRII) with its cognate transducer (NpHtrII), mediates negative phototaxis in halobacteria N. pharaonis. Upon light activation NpSRII triggers a signal transduction chain homologous to the two-component system in eubacterial chemotaxis. Here we report on crystal structures of the ground and active M-state of the complex in the space group I212121. We demonstrate that the relative orientation of symmetrical parts of the dimer is parallel ("U"-shaped) contrary to the gusset-like ("V"-shaped) form of the previously reported structures of the NpSRII/NpHtrII complex in the space group P21212, although the structures of the monomers taken individually are nearly the same. Computer modeling of the HAMP domain in the obtained "V"- and "U"-shaped structures revealed that only the "U"-shaped conformation allows for tight interactions of the receptor with the HAMP domain. This is in line with existing data and supports biological relevance of the "U" shape in the ground state. We suggest that the "V"-shaped structure may correspond to the active state of the complex and transition from the "U" to the "V"-shape of the receptor-transducer complex can be involved in signal transduction from the receptor to the signaling domain of NpHtrII.

-	~~Authors:~~ Ishchenko, A., Round, E., Borshchevskiy, V., Grudinin, S., Gushchin, I., Klare~~, J.~~, Remeeva, A., Polovinkin, V., Utrobin, P., Balandin, T., Engelhard, M~~., Bueldt~~, G., Gordeliy, V.	+	New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex.,Ishchenko A, Round E, Borshchevskiy V, Grudinin S, Gushchin I, Klare JP, Remeeva A, Polovinkin V, Utrobin P, Balandin T, Engelhard M, Buldt G, Gordeliy V Sci Rep. 2017 Feb 6;7:41811. doi: 10.1038/srep41811. PMID:28165484<ref>PMID:28165484</ref>

-	~~Description: Structure~~ of the ~~SRII~~/~~HtrII Complex in I212121 space group (~~""U"" ~~shape)~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category: Gordeliy, V]]~~	+	<div class="pdbe-citations 5jje" style="background-color:#fffaf0;"></div>
-	~~[[Category: Borshchevskiy, V]]~~	+	== References ==
-	~~[[Category: Ishchenko, A]]~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Balandin, T]]		[[Category: Balandin, T]]
-	[[Category: ~~Utrobin~~, ~~P]]~~	+	[[Category: Borshchevskiy, V]]
-	~~[[Category: Gushchin, I]]~~	+
-	~~[[Category: Remeeva, A~~]]	+
	[[Category: Bueldt, G]]		[[Category: Bueldt, G]]
-	[[Category: Grudinin, S]]
	[[Category: Engelhard, M]]		[[Category: Engelhard, M]]
		+	[[Category: Gordeliy, V]]
		+	[[Category: Grudinin, S]]
		+	[[Category: Gushchin, I]]
		+	[[Category: Ishchenko, A]]
	[[Category: Klare, J]]		[[Category: Klare, J]]
-	[[Category: Round, E]]
	[[Category: Polovinkin, V]]		[[Category: Polovinkin, V]]
		+	[[Category: Remeeva, A]]
		+	[[Category: Round, E]]
		+	[[Category: Utrobin, P]]
		+	[[Category: Membrane protein complex]]
		+	[[Category: Sensory rhodopsin ii]]
		+	[[Category: Signaling protein]]
		+	[[Category: Transducer]]

OCA: Protected "5jje" [edit=sysop:move=sysop]

OCA — Wed, 11 May 2016 02:09:56 GMT

Protected "5jje" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:09, 11 May 2016

OCA: New page: '''Unreleased structure''' The entry 5jje is ON HOLD until Paper Publication Authors: Ishchenko, A., Round, E., Borshchevskiy, V., Grudinin, S., Gushchin, I., Klare, J., Remeeva, A., Po...

OCA — Wed, 11 May 2016 02:09:55 GMT

New page: '''Unreleased structure''' The entry 5jje is ON HOLD until Paper Publication Authors: Ishchenko, A., Round, E., Borshchevskiy, V., Grudinin, S., Gushchin, I., Klare, J., Remeeva, A., Po...

New page

'''Unreleased structure'''

The entry 5jje is ON HOLD until Paper Publication

Authors: Ishchenko, A., Round, E., Borshchevskiy, V., Grudinin, S., Gushchin, I., Klare, J., Remeeva, A., Polovinkin, V., Utrobin, P., Balandin, T., Engelhard, M., Bueldt, G., Gordeliy, V.

Description: Structure of the SRII/HtrII Complex in I212121 space group (""U"" shape)
[[Category: Unreleased Structures]]
[[Category: Gordeliy, V]]
[[Category: Borshchevskiy, V]]
[[Category: Ishchenko, A]]
[[Category: Balandin, T]]
[[Category: Utrobin, P]]
[[Category: Gushchin, I]]
[[Category: Remeeva, A]]
[[Category: Bueldt, G]]
[[Category: Grudinin, S]]
[[Category: Engelhard, M]]
[[Category: Klare, J]]
[[Category: Round, E]]
[[Category: Polovinkin, V]]