5kh0 - Revision history

OCA at 10:46, 27 September 2023

OCA — Wed, 27 Sep 2023 10:46:32 GMT

←Older revision		Revision as of 10:46, 27 September 2023
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	<StructureSection load='5kh0' size='340' side='right'caption='[[5kh0]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='5kh0' size='340' side='right'caption='[[5kh0]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5kh0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KH0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5KH0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5kh0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermosipho_melanesiensis_BI429 Thermosipho melanesiensis BI429]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KH0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5kh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kh0 OCA], [~~http~~://pdbe.org/5kh0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5kh0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5kh0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5kh0 ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kh0 OCA], [https://pdbe.org/5kh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kh0 RCSB], [https://www.ebi.ac.uk/pdbsum/5kh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kh0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A6LMQ7_THEM4 A6LMQ7_THEM4]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Caserta, G~~]]	+	[[Category: Thermosipho melanesiensis BI429]]
-	[[Category: ~~Fontecave, M~~]]	+	[[Category: Caserta G]]
-	[[Category: ~~Pecqueur, L~~]]	+	[[Category: Fontecave M]]
-	[[Category: ~~Oxidoreductase~~]]	+	[[Category: Pecqueur L]]

OCA at 15:25, 8 July 2020

OCA — Wed, 08 Jul 2020 15:25:00 GMT

←Older revision		Revision as of 15:25, 8 July 2020
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	==Crystal Structure of HydF from thermosipho melanesiensis in complex with a [4Fe-4S] cluster==		==Crystal Structure of HydF from thermosipho melanesiensis in complex with a [4Fe-4S] cluster==
-	<StructureSection load='5kh0' size='340' side='right' caption='[[5kh0]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='5kh0' size='340' side='right'caption='[[5kh0]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5kh0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KH0 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5KH0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5kh0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KH0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5KH0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5kh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kh0 OCA], [http://pdbe.org/5kh0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kh0 RCSB], [http://www.ebi.ac.uk/pdbsum/5kh0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kh0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5kh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kh0 OCA], [http://pdbe.org/5kh0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kh0 RCSB], [http://www.ebi.ac.uk/pdbsum/5kh0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kh0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 5kh0" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5kh0" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[GTP-binding protein 3D structures\|GTP-binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Caserta, G]]		[[Category: Caserta, G]]
	[[Category: Fontecave, M]]		[[Category: Fontecave, M]]
	[[Category: Pecqueur, L]]		[[Category: Pecqueur, L]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 10:11, 3 August 2017

OCA — Thu, 03 Aug 2017 10:11:27 GMT

←Older revision		Revision as of 10:11, 3 August 2017
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kh0 OCA], [http://pdbe.org/5kh0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kh0 RCSB], [http://www.ebi.ac.uk/pdbsum/5kh0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kh0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kh0 OCA], [http://pdbe.org/5kh0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kh0 RCSB], [http://www.ebi.ac.uk/pdbsum/5kh0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kh0 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	[FeFe] hydrogenase (HydA) catalyzes interconversion between 2H+ and H2 at an active site composed of a [4Fe-4S] cluster linked to a 2Fe subcluster that harbors CO, CN- and azapropanedithiolate (adt2-) ligands. HydE, HydG and HydF are the maturases specifically involved in the biosynthesis of the 2Fe subcluster. Using ligands synthesized by HydE and HydG, HydF assembles a di-iron precursor of the 2Fe subcluster and transfers it to HydA for maturation. Here we report the first X-ray structure of HydF with its [4Fe-4S] cluster. The cluster is chelated by three cysteines and an exchangeable glutamate, which allows the binding of synthetic mimics of the 2Fe subcluster. [Fe2(adt)(CO)4(CN)2]2- is proposed to be the true di-iron precursor because, when bound to HydF, it matures HydA and displays features in Fourier transform infrared (FTIR) spectra that are similar to those of the native HydF active intermediate. A new route toward the generation of artificial hydrogenases, as combinations of HydF and such biomimetic complexes, is proposed on the basis of the observed hydrogenase activity of chemically modified HydF.
		+
		+	Structural and functional characterization of the hydrogenase-maturation HydF protein.,Caserta G, Pecqueur L, Adamska-Venkatesh A, Papini C, Roy S, Artero V, Atta M, Reijerse E, Lubitz W, Fontecave M Nat Chem Biol. 2017 Jul;13(7):779-784. doi: 10.1038/nchembio.2385. Epub 2017 May , 29. PMID:28553946<ref>PMID:28553946</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5kh0" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 13:08, 4 May 2017

OCA — Thu, 04 May 2017 13:08:52 GMT

←Older revision		Revision as of 13:08, 4 May 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5kh0 is ~~ON HOLD until Paper Publication~~	+	==Crystal Structure of HydF from thermosipho melanesiensis in complex with a [4Fe-4S] cluster==
-		+	<StructureSection load='5kh0' size='340' side='right' caption='[[5kh0]], [[Resolution\|resolution]] 2.80Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5kh0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KH0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KH0 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kh0 OCA], [http://pdbe.org/5kh0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kh0 RCSB], [http://www.ebi.ac.uk/pdbsum/5kh0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kh0 ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Caserta, G]]
		+	[[Category: Fontecave, M]]
		+	[[Category: Pecqueur, L]]
		+	[[Category: Oxidoreductase]]

OCA: Protected "5kh0" [edit=sysop:move=sysop]

OCA — Thu, 23 Jun 2016 21:36:06 GMT

Protected "5kh0" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:36, 23 June 2016

OCA: New page: '''Unreleased structure''' The entry 5kh0 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

OCA — Thu, 23 Jun 2016 21:36:05 GMT

New page: '''Unreleased structure''' The entry 5kh0 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5kh0 is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]