5kjh - Revision history

OCA at 10:47, 27 September 2023

OCA — Wed, 27 Sep 2023 10:47:43 GMT

←Older revision		Revision as of 10:47, 27 September 2023
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	<StructureSection load='5kjh' size='340' side='right'caption='[[5kjh]], [[Resolution\|resolution]] 2.27Å' scene=''>		<StructureSection load='5kjh' size='340' side='right'caption='[[5kjh]], [[Resolution\|resolution]] 2.27Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5kjh]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Chatd Chatd~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5ch1 5ch1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KJH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5KJH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5kjh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum_var._thermophilum_DSM_1495 Chaetomium thermophilum var. thermophilum DSM 1495] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5ch1 5ch1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KJH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KJH FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SAH:S~~-~~ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>~~, ~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.27Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene><~~/td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<~~tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td><td class="sblockDat">CTHT_0029920 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=759272 CHATD]), CTHT_0006210 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=759272 CHATD])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kjh OCA], [https://pdbe.org/5kjh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kjh RCSB], [https://www.ebi.ac.uk/pdbsum/5kjh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kjh ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5kjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kjh OCA], [~~http~~://pdbe.org/5kjh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5kjh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5kjh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5kjh ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/G0S8H7_CHATD G0S8H7_CHATD]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chatd~~]]	+	[[Category: Chaetomium thermophilum var. thermophilum DSM 1495]]
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Jiao, L]]	+	[[Category: Jiao L]]
-	[[Category: Liu, X]]	+	[[Category: Liu X]]
-	~~[[Category: Complex]]~~	+
-	~~[[Category: Methyltransferase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 15:26, 8 July 2020

OCA — Wed, 08 Jul 2020 15:26:48 GMT

←Older revision		Revision as of 15:26, 8 July 2020
Line 1:		Line 1:

	==Crystal structure of an active polycomb repressive complex 2 in the stimulated state==		==Crystal structure of an active polycomb repressive complex 2 in the stimulated state==
-	<StructureSection load='5kjh' size='340' side='right' caption='[[5kjh]], [[Resolution\|resolution]] 2.27Å' scene=''>	+	<StructureSection load='5kjh' size='340' side='right'caption='[[5kjh]], [[Resolution\|resolution]] 2.27Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5kjh]] is a 3 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5ch1 5ch1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KJH OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5KJH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5kjh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Chatd Chatd]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5ch1 5ch1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KJH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5KJH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5kjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kjh OCA], [http://pdbe.org/5kjh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kjh RCSB], [http://www.ebi.ac.uk/pdbsum/5kjh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kjh ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTHT_0029920 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=759272 CHATD]), CTHT_0006210 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=759272 CHATD])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5kjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kjh OCA], [http://pdbe.org/5kjh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kjh RCSB], [http://www.ebi.ac.uk/pdbsum/5kjh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kjh ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chatd]]
		+	[[Category: Large Structures]]
	[[Category: Jiao, L]]		[[Category: Jiao, L]]
	[[Category: Liu, X]]		[[Category: Liu, X]]

OCA at 12:54, 19 April 2017

OCA — Wed, 19 Apr 2017 12:54:06 GMT

←Older revision		Revision as of 12:54, 19 April 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5kjh is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of an active polycomb repressive complex 2 in the stimulated state==
		+	<StructureSection load='5kjh' size='340' side='right' caption='[[5kjh]], [[Resolution\|resolution]] 2.27Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5kjh]] is a 3 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5ch1 5ch1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KJH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KJH FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kjh OCA], [http://pdbe.org/5kjh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kjh RCSB], [http://www.ebi.ac.uk/pdbsum/5kjh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kjh ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Zhang et al suggested that in the crystal structure of a polycomb repressive complex 2 from Chaetomium thermophilum (ctPRC2), a flexible linker region, but not the H3K27M cancer mutant peptide, better fits the electron density. Based on our new data, we agree with this alternative interpretation and provide the crystal structure of ctPRC2 bound to a bona fide H3K27M sequence.

-	~~Authors: Jiao~~, L., Liu, X.	+	Response to Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".,Jiao L, Liu X Science. 2016 Dec 23;354(6319):1543. doi: 10.1126/science.aaj2335. PMID:28008038<ref>PMID:28008038</ref>

-	~~Description: Crystal structure~~ of ~~an active polycomb repressive complex 2 in~~ the ~~stimulated state~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 5kjh" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Jiao, L]]		[[Category: Jiao, L]]
	[[Category: Liu, X]]		[[Category: Liu, X]]
		+	[[Category: Complex]]
		+	[[Category: Methyltransferase]]
		+	[[Category: Transferase]]

OCA at 13:27, 10 August 2016

OCA — Wed, 10 Aug 2016 13:27:45 GMT

←Older revision		Revision as of 13:27, 10 August 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5kjh is ON HOLD until ~~Aug 15 2017~~	+	The entry 5kjh is ON HOLD until Paper Publication

	Authors: Jiao, L., Liu, X.		Authors: Jiao, L., Liu, X.

OCA at 12:28, 26 July 2016

OCA — Tue, 26 Jul 2016 12:28:13 GMT

←Older revision		Revision as of 12:28, 26 July 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5kjh is ON HOLD	+	The entry 5kjh is ON HOLD until Aug 15 2017

	Authors: Jiao, L., Liu, X.		Authors: Jiao, L., Liu, X.

OCA: Protected "5kjh" [edit=sysop:move=sysop]

OCA — Wed, 13 Jul 2016 00:25:38 GMT

Protected "5kjh" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:25, 13 July 2016

OCA: New page: '''Unreleased structure''' The entry 5kjh is ON HOLD Authors: Jiao, L., Liu, X. Description: Crystal structure of an active polycomb repressive complex 2 in the stimulated state [[Cate...

OCA — Wed, 13 Jul 2016 00:25:36 GMT

New page: '''Unreleased structure''' The entry 5kjh is ON HOLD Authors: Jiao, L., Liu, X. Description: Crystal structure of an active polycomb repressive complex 2 in the stimulated state [[Cate...

New page

'''Unreleased structure'''

The entry 5kjh is ON HOLD

Authors: Jiao, L., Liu, X.

Description: Crystal structure of an active polycomb repressive complex 2 in the stimulated state
[[Category: Unreleased Structures]]
[[Category: Jiao, L]]
[[Category: Liu, X]]