5knt - Revision history

OCA at 10:04, 27 September 2023

OCA — Wed, 27 Sep 2023 10:04:34 GMT

←Older revision		Revision as of 10:04, 27 September 2023
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	<StructureSection load='5knt' size='340' side='right'caption='[[5knt]], [[Resolution\|resolution]] 2.55Å' scene=''>		<StructureSection load='5knt' size='340' side='right'caption='[[5knt]], [[Resolution\|resolution]] 2.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5knt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5KNT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5knt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KNT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6WB:2-[[(2~{S})-2,3-bis(oxidanyl)propyl]-[2-(6-oxidanylidene-1~{H}-purin-9-yl)ethyl]amino]ethylphosphonic+acid'>6WB</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.55Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5knp\|5knp]], [[5knq\|5knq]], [[5kny\|5kny]], [[5knr\|5knr]], [[5kns\|5kns]], [[5knv\|5knv]], [[5knu\|5knu]], [[5knx\|5knx]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6WB:2-[[(2~{S})-2,3-bis(oxidanyl)propyl]-[2-(6-oxidanylidene-1~{H}-purin-9-yl)ethyl]amino]ethylphosphonic+acid'>6WB</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5knt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knt OCA], [~~http~~://pdbe.org/5knt PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5knt RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5knt PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5knt ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5knt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knt OCA], [https://pdbe.org/5knt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5knt RCSB], [https://www.ebi.ac.uk/pdbsum/5knt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5knt ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/HPRT_ECOLI HPRT_ECOLI] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine.

	==See Also==		==See Also==
Line 13:		Line 15:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Eng~~, W S~~]]	+	[[Category: Eng WS]]
-	[[Category: Hockova, D]]	+	[[Category: Hockova D]]
-	[[Category: Janeba, Z]]	+	[[Category: Janeba Z]]
-	[[Category: Keough~~, D T]]~~	+	[[Category: Keough DT]]
-	~~[[Category: Acyclic nucleoside phosphonate]]~~	+
-	~~[[Category: Echprt]]~~	+
-	~~[[Category: Phosphoribosyltransferase]]~~	+
-	~~[[Category: Transferase-inhibitor complex~~]]	+

OCA at 06:29, 5 August 2020

OCA — Wed, 05 Aug 2020 06:29:14 GMT

←Older revision		Revision as of 06:29, 5 August 2020
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	==Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 2-((2,3-Dihydroxypropyl)(2-(hypoxanthin-9-yl)ethyl)amino)ethylphosphonic acid==		==Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 2-((2,3-Dihydroxypropyl)(2-(hypoxanthin-9-yl)ethyl)amino)ethylphosphonic acid==
-	<StructureSection load='5knt' size='340' side='right' caption='[[5knt]], [[Resolution\|resolution]] 2.55Å' scene=''>	+	<StructureSection load='5knt' size='340' side='right'caption='[[5knt]], [[Resolution\|resolution]] 2.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5knt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNT OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5KNT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5knt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5KNT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6WB:2-[[(2~{S})-2,3-bis(oxidanyl)propyl]-[2-(6-oxidanylidene-1~{H}-purin-9-yl)ethyl]amino]ethylphosphonic+acid'>6WB</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6WB:2-[[(2~{S})-2,3-bis(oxidanyl)propyl]-[2-(6-oxidanylidene-1~{H}-purin-9-yl)ethyl]amino]ethylphosphonic+acid'>6WB</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5knp\|5knp]], [[5knq\|5knq]], [[5kny\|5kny]], [[5knr\|5knr]], [[5kns\|5kns]], [[5knv\|5knv]], [[5knu\|5knu]], [[5knx\|5knx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5knp\|5knp]], [[5knq\|5knq]], [[5kny\|5kny]], [[5knr\|5knr]], [[5kns\|5kns]], [[5knv\|5knv]], [[5knu\|5knu]], [[5knx\|5knx]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5knt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knt OCA], [http://pdbe.org/5knt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5knt RCSB], [http://www.ebi.ac.uk/pdbsum/5knt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5knt ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5knt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knt OCA], [http://pdbe.org/5knt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5knt RCSB], [http://www.ebi.ac.uk/pdbsum/5knt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5knt ProSAT]</span></td></tr>
	</table>		</table>
		+
		+	==See Also==
		+	*[[Phosphoribosyltransferase 3D structures\|Phosphoribosyltransferase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Eng, W S]]		[[Category: Eng, W S]]
	[[Category: Hockova, D]]		[[Category: Hockova, D]]

OCA at 16:02, 20 October 2017

OCA — Fri, 20 Oct 2017 16:02:08 GMT

←Older revision		Revision as of 16:02, 20 October 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 5knt is ON HOLD until Paper Publication~~	+	==Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 2-((2,3-Dihydroxypropyl)(2-(hypoxanthin-9-yl)ethyl)amino)ethylphosphonic acid==
-		+	<StructureSection load='5knt' size='340' side='right' caption='[[5knt]], [[Resolution\|resolution]] 2.55Å' scene=''>
-	~~Authors: Eng, W.S., Keough, D.T., Hockova, D., Janeba, Z.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5knt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KNT FirstGlance]. <br>
-	~~Description:~~ Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 2-((2,3-Dihydroxypropyl)(2-(hypoxanthin-9-yl)ethyl)amino)ethylphosphonic acid	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6WB:2-[[(2~{S})-2,3-bis(oxidanyl)propyl]-[2-(6-oxidanylidene-1~{H}-purin-9-yl)ethyl]amino]ethylphosphonic+acid'>6WB</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5knp\|5knp]], [[5knq\|5knq]], [[5kny\|5kny]], [[5knr\|5knr]], [[5kns\|5kns]], [[5knv\|5knv]], [[5knu\|5knu]], [[5knx\|5knx]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5knt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knt OCA], [http://pdbe.org/5knt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5knt RCSB], [http://www.ebi.ac.uk/pdbsum/5knt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5knt ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Eng, W S]]
	[[Category: Hockova, D]]		[[Category: Hockova, D]]
-	[[Category: Eng, W.S]]
-	[[Category: Keough, D.T]]
	[[Category: Janeba, Z]]		[[Category: Janeba, Z]]
		+	[[Category: Keough, D T]]
		+	[[Category: Acyclic nucleoside phosphonate]]
		+	[[Category: Echprt]]
		+	[[Category: Phosphoribosyltransferase]]
		+	[[Category: Transferase-inhibitor complex]]

OCA at 10:20, 9 March 2017

OCA — Thu, 09 Mar 2017 10:20:56 GMT

←Older revision		Revision as of 10:20, 9 March 2017
Line 7:		Line 7:
	Description: Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 2-((2,3-Dihydroxypropyl)(2-(hypoxanthin-9-yl)ethyl)amino)ethylphosphonic acid		Description: Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 2-((2,3-Dihydroxypropyl)(2-(hypoxanthin-9-yl)ethyl)amino)ethylphosphonic acid
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Hockova, D]]
	[[Category: Eng, W.S]]		[[Category: Eng, W.S]]
	[[Category: Keough, D.T]]		[[Category: Keough, D.T]]
-	[[Category: Hockova, D]]
	[[Category: Janeba, Z]]		[[Category: Janeba, Z]]

OCA at 13:10, 27 July 2016

OCA — Wed, 27 Jul 2016 13:10:21 GMT

←Older revision		Revision as of 13:10, 27 July 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5knt is ON HOLD	+	The entry 5knt is ON HOLD until Paper Publication

	Authors: Eng, W.S., Keough, D.T., Hockova, D., Janeba, Z.		Authors: Eng, W.S., Keough, D.T., Hockova, D., Janeba, Z.

OCA at 12:37, 26 July 2016

OCA — Tue, 26 Jul 2016 12:37:34 GMT

←Older revision		Revision as of 12:37, 26 July 2016
Line 3:		Line 3:
	The entry 5knt is ON HOLD		The entry 5knt is ON HOLD

-	Authors: Eng, W.S., Keough, D.T., Hockova, D., Janeba, ~~Zlatko~~	+	Authors: Eng, W.S., Keough, D.T., Hockova, D., Janeba, Z.

	Description: Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 2-((2,3-Dihydroxypropyl)(2-(hypoxanthin-9-yl)ethyl)amino)ethylphosphonic acid		Description: Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 2-((2,3-Dihydroxypropyl)(2-(hypoxanthin-9-yl)ethyl)amino)ethylphosphonic acid
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Janeba, Zlatko]]
	[[Category: Eng, W.S]]		[[Category: Eng, W.S]]
	[[Category: Keough, D.T]]		[[Category: Keough, D.T]]
	[[Category: Hockova, D]]		[[Category: Hockova, D]]
		+	[[Category: Janeba, Z]]

OCA: Protected "5knt" [edit=sysop:move=sysop]

OCA — Wed, 13 Jul 2016 00:37:38 GMT

Protected "5knt" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:37, 13 July 2016

OCA: New page: '''Unreleased structure''' The entry 5knt is ON HOLD Authors: Eng, W.S., Keough, D.T., Hockova, D., Janeba, Zlatko Description: Crystal structure of E. coli hypoxanthine phosphoribosyl...

OCA — Wed, 13 Jul 2016 00:37:37 GMT

New page: '''Unreleased structure''' The entry 5knt is ON HOLD Authors: Eng, W.S., Keough, D.T., Hockova, D., Janeba, Zlatko Description: Crystal structure of E. coli hypoxanthine phosphoribosyl...

New page

'''Unreleased structure'''

The entry 5knt is ON HOLD

Authors: Eng, W.S., Keough, D.T., Hockova, D., Janeba, Zlatko

Description: Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 2-((2,3-Dihydroxypropyl)(2-(hypoxanthin-9-yl)ethyl)amino)ethylphosphonic acid
[[Category: Unreleased Structures]]
[[Category: Janeba, Zlatko]]
[[Category: Eng, W.S]]
[[Category: Keough, D.T]]
[[Category: Hockova, D]]