5lki - Revision history

OCA at 18:31, 18 October 2023

OCA — Wed, 18 Oct 2023 18:31:58 GMT

←Older revision		Revision as of 18:31, 18 October 2023
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	<SX load='5lki' size='340' side='right' viewer='molstar' caption='[[5lki]], [[Resolution\|resolution]] 3.46Å' scene=''>		<SX load='5lki' size='340' side='right' viewer='molstar' caption='[[5lki]], [[Resolution\|resolution]] 3.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5lki]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_29999 Atcc 29999~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5LKI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5lki]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Photorhabdus_luminescens Photorhabdus luminescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LKI FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[5lkh\|5lkh]]</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.46Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">tcdA, tcdA1 ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=29488 ATCC 29999])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lki OCA], [https://pdbe.org/5lki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lki RCSB], [https://www.ebi.ac.uk/pdbsum/5lki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lki ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5lki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lki OCA], [~~http~~://pdbe.org/5lki PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5lki RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5lki PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5lki ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9RN43_PHOLU Q9RN43_PHOLU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 22:
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: Atcc 29999]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gatsogiannis, C]]	+	[[Category: Photorhabdus luminescens]]
-	[[Category: Leidreiter, F]]	+	[[Category: Gatsogiannis C]]
-	[[Category: Merino, F]]	+	[[Category: Leidreiter F]]
-	[[Category: Meusch, D]]	+	[[Category: Merino F]]
-	[[Category: Prumbaum, D]]	+	[[Category: Meusch D]]
-	[[Category: Raunser, S]]	+	[[Category: Prumbaum D]]
-	[[Category: Roderer, D]]	+	[[Category: Raunser S]]
-	~~[[Category: Injection]]~~	+	[[Category: Roderer D]]
-	~~[[Category: Nanodisc]]~~	+
-	~~[[Category: Pore-forming]]~~	+
-	~~[[Category: Toxin~~]]	+

OCA at 20:42, 10 April 2020

OCA — Fri, 10 Apr 2020 20:42:23 GMT

←Older revision		Revision as of 20:42, 10 April 2020
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	<SX load='5lki' size='340' side='right' viewer='molstar' caption='[[5lki]], [[Resolution\|resolution]] 3.46Å' scene=''>		<SX load='5lki' size='340' side='right' viewer='molstar' caption='[[5lki]], [[Resolution\|resolution]] 3.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5lki]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29999 Atcc 29999]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKI OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5LKI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5lki]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29999 Atcc 29999]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5LKI FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5lkh\|5lkh]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5lkh\|5lkh]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tcdA, tcdA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29488 ATCC 29999])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tcdA, tcdA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29488 ATCC 29999])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5lki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lki OCA], [http://pdbe.org/5lki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lki RCSB], [http://www.ebi.ac.uk/pdbsum/5lki PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lki ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5lki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lki OCA], [http://pdbe.org/5lki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lki RCSB], [http://www.ebi.ac.uk/pdbsum/5lki PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lki ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 18:58, 6 March 2020

OCA — Fri, 06 Mar 2020 18:58:13 GMT

←Older revision		Revision as of 18:58, 6 March 2020
Line 1:		Line 1:

	==Cryo-EM structure of the Tc toxin TcdA1 in its pore state==		==Cryo-EM structure of the Tc toxin TcdA1 in its pore state==
-	<~~StructureSection~~ load='5lki' size='340' side='right'caption='[[5lki]], [[Resolution\|resolution]] 3.46Å' scene=''>	+	<SX load='5lki' size='340' side='right' viewer='molstar' caption='[[5lki]], [[Resolution\|resolution]] 3.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5lki]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29999 Atcc 29999]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LKI FirstGlance]. <br>		<table><tr><td colspan='2'>[[5lki]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29999 Atcc 29999]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LKI FirstGlance]. <br>
Line 20:		Line 20:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Atcc 29999]]		[[Category: Atcc 29999]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 07:41, 23 October 2019

OCA — Wed, 23 Oct 2019 07:41:03 GMT

←Older revision		Revision as of 07:41, 23 October 2019
Line 1:		Line 1:

	==Cryo-EM structure of the Tc toxin TcdA1 in its pore state==		==Cryo-EM structure of the Tc toxin TcdA1 in its pore state==
-	<StructureSection load='5lki' size='340' side='right' caption='[[5lki]], [[Resolution\|resolution]] 3.46Å' scene=''>	+	<StructureSection load='5lki' size='340' side='right'caption='[[5lki]], [[Resolution\|resolution]] 3.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5lki]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29999 Atcc 29999]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LKI FirstGlance]. <br>		<table><tr><td colspan='2'>[[5lki]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29999 Atcc 29999]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LKI FirstGlance]. <br>
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 29999]]		[[Category: Atcc 29999]]
		+	[[Category: Large Structures]]
	[[Category: Gatsogiannis, C]]		[[Category: Gatsogiannis, C]]
	[[Category: Leidreiter, F]]		[[Category: Leidreiter, F]]

OCA at 03:26, 16 November 2017

OCA — Thu, 16 Nov 2017 03:26:44 GMT

←Older revision		Revision as of 03:26, 16 November 2017
Line 3:		Line 3:
	<StructureSection load='5lki' size='340' side='right' caption='[[5lki]], [[Resolution\|resolution]] 3.46Å' scene=''>		<StructureSection load='5lki' size='340' side='right' caption='[[5lki]], [[Resolution\|resolution]] 3.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5lki]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LKI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5lki]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29999 Atcc 29999]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LKI FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5lkh\|5lkh]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5lkh\|5lkh]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tcdA, tcdA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29488 ATCC 29999])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lki OCA], [http://pdbe.org/5lki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lki RCSB], [http://www.ebi.ac.uk/pdbsum/5lki PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lki ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lki OCA], [http://pdbe.org/5lki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lki RCSB], [http://www.ebi.ac.uk/pdbsum/5lki PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lki ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 29999]]
	[[Category: Gatsogiannis, C]]		[[Category: Gatsogiannis, C]]
	[[Category: Leidreiter, F]]		[[Category: Leidreiter, F]]

OCA at 05:39, 9 September 2016

OCA — Fri, 09 Sep 2016 05:39:24 GMT

←Older revision		Revision as of 05:39, 9 September 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5lki is ~~ON HOLD~~	+	==Cryo-EM structure of the Tc toxin TcdA1 in its pore state==
		+	<StructureSection load='5lki' size='340' side='right' caption='[[5lki]], [[Resolution\|resolution]] 3.46Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5lki]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LKI FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5lkh\|5lkh]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lki OCA], [http://pdbe.org/5lki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lki RCSB], [http://www.ebi.ac.uk/pdbsum/5lki PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lki ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Tc toxins from pathogenic bacteria use a special syringe-like mechanism to perforate the host cell membrane and inject a deadly enzyme into the host cytosol. The molecular mechanism of this unusual injection system is poorly understood. Using electron cryomicroscopy, we determined the structure of TcdA1 from Photorhabdus luminescens embedded in lipid nanodiscs. In our structure, compared with the previous structure of TcdA1 in the prepore state, the transmembrane helices rearrange in the membrane and open the initially closed pore. However, the helices do not span the complete membrane; instead, the loops connecting the helices form the rim of the funnel. Lipid head groups reach into the space between the loops and consequently stabilize the pore conformation. The linker domain is folded and packed into a pocket formed by the other domains of the toxin, thereby considerably contributing to stabilization of the pore state.

-	~~Authors~~:	+	Membrane insertion of a Tc toxin in near-atomic detail.,Gatsogiannis C, Merino F, Prumbaum D, Roderer D, Leidreiter F, Meusch D, Raunser S Nat Struct Mol Biol. 2016 Aug 29. doi: 10.1038/nsmb.3281. PMID:27571177<ref>PMID:27571177</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5lki" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Gatsogiannis, C]]
		+	[[Category: Leidreiter, F]]
		+	[[Category: Merino, F]]
		+	[[Category: Meusch, D]]
		+	[[Category: Prumbaum, D]]
		+	[[Category: Raunser, S]]
		+	[[Category: Roderer, D]]
		+	[[Category: Injection]]
		+	[[Category: Nanodisc]]
		+	[[Category: Pore-forming]]
		+	[[Category: Toxin]]

OCA: Protected "5lki" [edit=sysop:move=sysop]

OCA — Wed, 27 Jul 2016 14:04:08 GMT

Protected "5lki" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:04, 27 July 2016

OCA: New page: '''Unreleased structure''' The entry 5lki is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 27 Jul 2016 14:04:07 GMT

New page: '''Unreleased structure''' The entry 5lki is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5lki is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]