5loy - Revision history

OCA at 18:38, 18 October 2023

OCA — Wed, 18 Oct 2023 18:38:12 GMT

←Older revision		Revision as of 18:38, 18 October 2023
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	<StructureSection load='5loy' size='340' side='right'caption='[[5loy]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='5loy' size='340' side='right'caption='[[5loy]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5loy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LOY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5LOY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5loy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LOY FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5loy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5loy OCA], [~~http~~://pdbe.org/5loy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5loy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5loy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5loy ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5loy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5loy OCA], [https://pdbe.org/5loy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5loy RCSB], [https://www.ebi.ac.uk/pdbsum/5loy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5loy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Albrecht, R~~]]	+	[[Category: Synthetic construct]]
-	[[Category: ~~Fuchs, A C.D~~]]	+	[[Category: Albrecht R]]
-	[[Category: ~~Hartmann, M D~~]]	+	[[Category: Fuchs ACD]]
-	[[Category: ~~Martin, J~~]]	+	[[Category: Hartmann MD]]
-	[[Category: ~~Ancestral beta subunit]]~~	+	[[Category: Martin J]]
-	~~[[Category: Consensus design]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Metal binding protein]]~~	+
-	~~[[Category: Proteasome precursor]]~~	+
-	~~[[Category: Protein degradation~~]]	+

OCA at 10:44, 12 August 2020

OCA — Wed, 12 Aug 2020 10:44:47 GMT

←Older revision		Revision as of 10:44, 12 August 2020
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	==Helical Assembly of a Designed Anbu Protein==		==Helical Assembly of a Designed Anbu Protein==
-	<StructureSection load='5loy' size='340' side='right' caption='[[5loy]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='5loy' size='340' side='right'caption='[[5loy]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5loy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LOY OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5LOY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5loy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LOY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5LOY FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5loy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5loy OCA], [http://pdbe.org/5loy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5loy RCSB], [http://www.ebi.ac.uk/pdbsum/5loy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5loy ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5loy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5loy OCA], [http://pdbe.org/5loy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5loy RCSB], [http://www.ebi.ac.uk/pdbsum/5loy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5loy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Albrecht, R]]		[[Category: Albrecht, R]]
	[[Category: Fuchs, A C.D]]		[[Category: Fuchs, A C.D]]

OCA at 09:28, 3 August 2017

OCA — Thu, 03 Aug 2017 09:28:16 GMT

←Older revision		Revision as of 09:28, 3 August 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5loy is ~~ON HOLD~~	+	==Helical Assembly of a Designed Anbu Protein==
		+	<StructureSection load='5loy' size='340' side='right' caption='[[5loy]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5loy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LOY FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5loy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5loy OCA], [http://pdbe.org/5loy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5loy RCSB], [http://www.ebi.ac.uk/pdbsum/5loy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5loy ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Proteasomes are self-compartmentalizing proteases that function at the core of the cellular protein degradation machinery in eukaryotes, archaea, and some bacteria. Although their evolutionary history is under debate, it is thought to be linked to that of the bacterial protease HslV and the hypothetical bacterial protease Anbu (ancestral beta subunit). Here, together with an extensive bioinformatic analysis, we present the first biophysical characterization of Anbu. Anbu forms a dodecameric complex with a unique architecture that was only accessible through the combination of X-ray crystallography and small-angle X-ray scattering. While forming continuous helices in crystals and electron microscopy preparations, refinement of sections from the crystal structure against the scattering data revealed a helical open-ring structure in solution, contrasting the ring-shaped structures of proteasome and HslV. Based on this primordial architecture and exhaustive sequence comparisons, we propose that Anbu represents an ancestral precursor at the origin of self-compartmentalization.

-	~~Authors~~:	+	The Architecture of the Anbu Complex Reflects an Evolutionary Intermediate at the Origin of the Proteasome System.,Fuchs ACD, Alva V, Maldoner L, Albrecht R, Hartmann MD, Martin J Structure. 2017 Jun 6;25(6):834-845.e5. doi: 10.1016/j.str.2017.04.005. Epub 2017, May 4. PMID:28479063<ref>PMID:28479063</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5loy" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Albrecht, R]]
		+	[[Category: Fuchs, A C.D]]
		+	[[Category: Hartmann, M D]]
		+	[[Category: Martin, J]]
		+	[[Category: Ancestral beta subunit]]
		+	[[Category: Consensus design]]
		+	[[Category: Hydrolase]]
		+	[[Category: Metal binding protein]]
		+	[[Category: Proteasome precursor]]
		+	[[Category: Protein degradation]]

OCA: Protected "5loy" [edit=sysop:move=sysop]

OCA — Fri, 09 Sep 2016 15:08:09 GMT

Protected "5loy" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:08, 9 September 2016

OCA: New page: '''Unreleased structure''' The entry 5loy is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Fri, 09 Sep 2016 15:08:08 GMT

New page: '''Unreleased structure''' The entry 5loy is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5loy is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]