5lsf - Revision history

OCA at 18:44, 18 October 2023

OCA — Wed, 18 Oct 2023 18:44:53 GMT

←Older revision		Revision as of 18:44, 18 October 2023
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	<StructureSection load='5lsf' size='340' side='right'caption='[[5lsf]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='5lsf' size='340' side='right'caption='[[5lsf]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5lsf]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Sacbrood_virus Sacbrood virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LSF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5LSF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5lsf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sacbrood_virus Sacbrood virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LSF FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lsf OCA], [~~http~~://pdbe.org/5lsf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5lsf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5lsf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5lsf ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lsf OCA], [https://pdbe.org/5lsf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lsf RCSB], [https://www.ebi.ac.uk/pdbsum/5lsf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lsf ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A2S0CUG6_9VIRU A0A2S0CUG6_9VIRU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Sacbrood virus]]		[[Category: Sacbrood virus]]
-	[[Category: Plevka, P]]	+	[[Category: Plevka P]]
-	[[Category: Veselikova, M]]	+	[[Category: Veselikova M]]
-	~~[[Category: External vp4]]~~	+
-	~~[[Category: Iflaviridae]]~~	+
-	~~[[Category: Virus~~]]	+

OCA at 10:48, 12 August 2020

OCA — Wed, 12 Aug 2020 10:48:46 GMT

←Older revision		Revision as of 10:48, 12 August 2020
Line 1:		Line 1:

	==Sacbrood honeybee virus==		==Sacbrood honeybee virus==
-	<StructureSection load='5lsf' size='340' side='right' caption='[[5lsf]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='5lsf' size='340' side='right'caption='[[5lsf]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5lsf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sacbrood_virus Sacbrood virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LSF OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5LSF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5lsf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sacbrood_virus Sacbrood virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LSF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5LSF FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lsf OCA], [http://pdbe.org/5lsf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lsf RCSB], [http://www.ebi.ac.uk/pdbsum/5lsf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lsf ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lsf OCA], [http://pdbe.org/5lsf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lsf RCSB], [http://www.ebi.ac.uk/pdbsum/5lsf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lsf ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Sacbrood virus]]		[[Category: Sacbrood virus]]
	[[Category: Plevka, P]]		[[Category: Plevka, P]]

OCA at 18:33, 1 August 2018

OCA — Wed, 01 Aug 2018 18:33:01 GMT

←Older revision		Revision as of 18:33, 1 August 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 5lsf is ~~ON HOLD until Paper~~ Publication	+	==Sacbrood honeybee virus==
		+	<StructureSection load='5lsf' size='340' side='right' caption='[[5lsf]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5lsf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sacbrood_virus Sacbrood virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LSF FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lsf OCA], [http://pdbe.org/5lsf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lsf RCSB], [http://www.ebi.ac.uk/pdbsum/5lsf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lsf ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Infection by sacbrood virus (SBV) from the family Iflaviridae is lethal to honey bee larvae but only rarely causes the collapse of honey bee colonies. Despite the negative effect of SBV on honey bees, the structure of its particles and mechanism of its genome delivery are unknown. Here we present the crystal structure of SBV virion and show that it contains 60 copies of a minor capsid protein (MiCP) attached to the virion surface. No similar MiCPs have been previously reported in any of the related viruses from the order Picornavirales. The location of the MiCP coding sequence within the SBV genome indicates that the MiCP evolved from a C-terminal extension of a major capsid protein by the introduction of a cleavage site for a virus protease. The exposure of SBV to acidic pH, which the virus likely encounters during cell entry, induces the formation of pores at threefold and fivefold axes of the capsid that are 7 A and 12 A in diameter, respectively. This is in contrast to vertebrate picornaviruses, in which the pores along twofold icosahedral symmetry axes are currently considered the most likely sites for genome release. SBV virions lack VP4 subunits that facilitate the genome delivery of many related dicistroviruses and picornaviruses. MiCP subunits induce liposome disruption in vitro, indicating that they are functional analogs of VP4 subunits and enable the virus genome to escape across the endosome membrane into the cell cytoplasm.

-	~~Authors~~:	+	Virion structure and genome delivery mechanism of sacbrood honeybee virus.,Prochazkova M, Fuzik T, Skubnik K, Moravcova J, Ubiparip Z, Pridal A, Plevka P Proc Natl Acad Sci U S A. 2018 Jul 9. pii: 1722018115. doi:, 10.1073/pnas.1722018115. PMID:29987012<ref>PMID:29987012</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5lsf" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Sacbrood virus]]
		+	[[Category: Plevka, P]]
		+	[[Category: Veselikova, M]]
		+	[[Category: External vp4]]
		+	[[Category: Iflaviridae]]
		+	[[Category: Virus]]

OCA at 13:37, 14 September 2016

OCA — Wed, 14 Sep 2016 13:37:46 GMT

←Older revision		Revision as of 13:37, 14 September 2016
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5lsf is ON HOLD	+	The entry 5lsf is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5lsf" [edit=sysop:move=sysop]

OCA — Fri, 09 Sep 2016 15:16:30 GMT

Protected "5lsf" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:16, 9 September 2016

OCA: New page: '''Unreleased structure''' The entry 5lsf is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Fri, 09 Sep 2016 15:16:29 GMT

New page: '''Unreleased structure''' The entry 5lsf is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5lsf is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]