5m1z - Revision history

OCA at 18:20, 1 November 2023

OCA — Wed, 01 Nov 2023 18:20:25 GMT

←Older revision		Revision as of 18:20, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='5m1z' size='340' side='right'caption='[[5m1z]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='5m1z' size='340' side='right'caption='[[5m1z]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5m1z]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Fusairum_graminearum Fusairum~~ graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M1Z OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5M1Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5m1z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_graminearum Fusarium graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M1Z FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=EDO:1~~,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=AHR:ALPHA-L-ARABINOFURANOSE'>AHR</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=6LW:(2~{Z},3~{R},4~{R},5~{S})-2-HYDROXYIMINO-5-(HYDROXYMETHYL)OXOLANE-3,4-DIOL'>6LW</scene><~~/td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6LW:(2~{Z},3~{R},4~{R},5~{S})-2-HYDROXYIMINO-5-(HYDROXYMETHYL)OXOLANE-3,4-DIOL'>6LW</scene>, <scene name='pdbligand=AHR:ALPHA-L-ARABINOFURANOSE'>AHR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<~~tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td><~~td class~~=~~"sblockDat">arb93a ([http~~:~~//www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5518 Fusairum graminearum])</td~~></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m1z OCA], [https://pdbe.org/5m1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m1z RCSB], [https://www.ebi.ac.uk/pdbsum/5m1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m1z ProSAT]</span></td></tr>
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>[http://en.wikipedia.org/wiki/Non-reducing_end_alpha-L-arabinofuranosidase Non-reducing end alpha-L-arabinofuranosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.55 3.2.1.55] </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5m1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m1z OCA], [~~http~~://pdbe.org/5m1z PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5m1z RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5m1z PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5m1z ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B8ZY56_GIBZA B8ZY56_GIBZA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Fusairum~~ graminearum]]	+	[[Category: Fusarium graminearum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Non-reducing end alpha-L-arabinofuranosidase]]~~	+	[[Category: Varrot A]]
-	[[Category: Varrot, A]]	+
-	~~[[Category: Arabinofuramisodase]]~~	+
-	~~[[Category: Complex]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Inhibitor~~]]	+

OCA at 10:58, 12 August 2020

OCA — Wed, 12 Aug 2020 10:58:56 GMT

←Older revision		Revision as of 10:58, 12 August 2020
Line 1:		Line 1:

	==STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEX WITH AN hydroximolactone INHIBITOR==		==STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEX WITH AN hydroximolactone INHIBITOR==
-	<StructureSection load='5m1z' size='340' side='right' caption='[[5m1z]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='5m1z' size='340' side='right'caption='[[5m1z]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5m1z]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M1Z OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5M1Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5m1z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusairum_graminearum Fusairum graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M1Z OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5M1Z FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~6LW~~:~~(2~{Z}~~,~~3~{R},4~{R},5~{S})-~~2-~~HYDROXYIMINO-5-(HYDROXYMETHYL)OXOLANE-3,4-DIOL~~'>~~6LW~~</scene>, <scene name='pdbligand=~~AHR~~:~~ALPHA-L-ARABINOFURANOSE~~'>~~AHR~~</scene>, <scene name='pdbligand=~~EDO~~:~~1,2-ETHANEDIOL~~'>~~EDO~~</scene>, <scene name='pdbligand=~~GOL~~:~~GLYCEROL~~'>~~GOL~~</scene>, <scene name='pdbligand=MN:~~MANGANESE+(II)+ION~~'>MN</scene>, <scene name='pdbligand=~~SO4~~:~~SULFATE+ION~~'>~~SO4~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=AHR:ALPHA-L-ARABINOFURANOSE'>AHR</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=6LW:(2~{Z},3~{R},4~{R},5~{S})-2-HYDROXYIMINO-5-(HYDROXYMETHYL)OXOLANE-3,4-DIOL'>6LW</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">arb93a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5518 Fusairum graminearum])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-reducing_end_alpha-L-arabinofuranosidase Non-reducing end alpha-L-arabinofuranosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.55 3.2.1.55] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-reducing_end_alpha-L-arabinofuranosidase Non-reducing end alpha-L-arabinofuranosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.55 3.2.1.55] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5m1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m1z OCA], [http://pdbe.org/5m1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m1z RCSB], [http://www.ebi.ac.uk/pdbsum/5m1z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m1z ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5m1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m1z OCA], [http://pdbe.org/5m1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m1z RCSB], [http://www.ebi.ac.uk/pdbsum/5m1z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m1z ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Fusairum graminearum]]
		+	[[Category: Large Structures]]
	[[Category: Non-reducing end alpha-L-arabinofuranosidase]]		[[Category: Non-reducing end alpha-L-arabinofuranosidase]]
	[[Category: Varrot, A]]		[[Category: Varrot, A]]

OCA at 09:44, 22 March 2017

OCA — Wed, 22 Mar 2017 09:44:40 GMT

←Older revision		Revision as of 09:44, 22 March 2017
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m1z OCA], [http://pdbe.org/5m1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m1z RCSB], [http://www.ebi.ac.uk/pdbsum/5m1z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m1z ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m1z OCA], [http://pdbe.org/5m1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m1z RCSB], [http://www.ebi.ac.uk/pdbsum/5m1z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m1z ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The synthesis of potent inhibitors of GH93 arabinanases as well as a synthesis of a chromogenic substrate to measure GH93 arabinanase activity is described. An insight into the reasons behind the potency of the inhibitors was gained through X-ray crystallographic analysis using the arabinanase Arb93A from Fusarium graminearum. These compounds lay a foundation for future inhibitor development as well as for the use of the chromogenic substrate in biochemical studies of GH93 arabinanases.
		+
		+	Exploiting sp2-hybridization in the development of potent 1,5-a-L-arabinanase inhibitors.,Coyle T, Debowski A, Varrot A, Stubbs KA Chembiochem. 2017 Mar 7. doi: 10.1002/cbic.201700073. PMID:28266777<ref>PMID:28266777</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5m1z" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 16:26, 2 January 2017

OCA — Mon, 02 Jan 2017 16:26:24 GMT

←Older revision		Revision as of 16:26, 2 January 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 5m1z is ON HOLD until Dec 06 2017~~	+	==STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEX WITH AN hydroximolactone INHIBITOR==
-		+	<StructureSection load='5m1z' size='340' side='right' caption='[[5m1z]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~Authors: Varrot, A.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5m1z]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M1Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M1Z FirstGlance]. <br>
-	~~Description:~~ STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEX WITH AN hydroximolactone INHIBITOR	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6LW:(2~{Z},3~{R},4~{R},5~{S})-2-HYDROXYIMINO-5-(HYDROXYMETHYL)OXOLANE-3,4-DIOL'>6LW</scene>, <scene name='pdbligand=AHR:ALPHA-L-ARABINOFURANOSE'>AHR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-reducing_end_alpha-L-arabinofuranosidase Non-reducing end alpha-L-arabinofuranosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.55 3.2.1.55] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m1z OCA], [http://pdbe.org/5m1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m1z RCSB], [http://www.ebi.ac.uk/pdbsum/5m1z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m1z ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Non-reducing end alpha-L-arabinofuranosidase]]
	[[Category: Varrot, A]]		[[Category: Varrot, A]]
		+	[[Category: Arabinofuramisodase]]
		+	[[Category: Complex]]
		+	[[Category: Hydrolase]]
		+	[[Category: Inhibitor]]

OCA at 18:34, 22 December 2016

OCA — Thu, 22 Dec 2016 18:34:40 GMT

←Older revision		Revision as of 18:34, 22 December 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5m1z is ON HOLD	+	The entry 5m1z is ON HOLD until Dec 06 2017

	Authors: Varrot, A.		Authors: Varrot, A.

OCA at 15:48, 15 December 2016

OCA — Thu, 15 Dec 2016 15:48:29 GMT

←Older revision		Revision as of 15:48, 15 December 2016
Line 5:		Line 5:
	Authors: Varrot, A.		Authors: Varrot, A.

-	Description: STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN ~~COMPLEXE~~ WITH AN hydroximolactone INHIBITOR	+	Description: STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEX WITH AN hydroximolactone INHIBITOR
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Varrot, A]]		[[Category: Varrot, A]]

OCA at 16:18, 9 December 2016

OCA — Fri, 09 Dec 2016 16:18:13 GMT

←Older revision		Revision as of 16:18, 9 December 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5m1z is ON HOLD ~~until sometime in the future~~	+	The entry 5m1z is ON HOLD

-	Authors: Varrot, A	+	Authors: Varrot, A.

	Description: STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEXE WITH AN hydroximolactone INHIBITOR		Description: STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEXE WITH AN hydroximolactone INHIBITOR
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Varrot, A]]		[[Category: Varrot, A]]

OCA: Protected "5m1z" [edit=sysop:move=sysop]

OCA — Wed, 19 Oct 2016 15:05:10 GMT

Protected "5m1z" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:05, 19 October 2016

OCA: New page: '''Unreleased structure''' The entry 5m1z is ON HOLD until sometime in the future Authors: Varrot, A Description: STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAM...

OCA — Wed, 19 Oct 2016 15:05:08 GMT

New page: '''Unreleased structure''' The entry 5m1z is ON HOLD until sometime in the future Authors: Varrot, A Description: STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAM...

New page

'''Unreleased structure'''

The entry 5m1z is ON HOLD until sometime in the future

Authors: Varrot, A

Description: STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEXE WITH AN hydroximolactone INHIBITOR
[[Category: Unreleased Structures]]
[[Category: Varrot, A]]