5mvl - Revision history

OCA at 17:51, 8 November 2023

OCA — Wed, 08 Nov 2023 17:51:29 GMT

←Older revision		Revision as of 17:51, 8 November 2023
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	<StructureSection load='5mvl' size='340' side='right'caption='[[5mvl]], [[Resolution\|resolution]] 1.41Å' scene=''>		<StructureSection load='5mvl' size='340' side='right'caption='[[5mvl]], [[Resolution\|resolution]] 1.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5mvl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MVL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5MVL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5mvl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MVL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MVL FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=MG:MAGNESIUM+ION'>MG</scene~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.405Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5mvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mvl OCA], [~~http~~://pdbe.org/5mvl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5mvl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5mvl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5mvl ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mvl OCA], [https://pdbe.org/5mvl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mvl RCSB], [https://www.ebi.ac.uk/pdbsum/5mvl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mvl ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Brown, T~~]]	+	[[Category: Synthetic construct]]
-	[[Category: ~~Hardwick, J S~~]]	+	[[Category: Brown T]]
-	[[Category: ~~Phillips, S E.V~~]]	+	[[Category: Hardwick JS]]
-	[[Category: ~~Ptchelkine, D~~]]	+	[[Category: Phillips SEV]]
-	[[Category: ~~5-bromouracil]]~~	+	[[Category: Ptchelkine D]]
-	~~[[Category: A-dna]]~~	+
-	~~[[Category: Cpg]]~~	+
-	~~[[Category: Dna~~]]	+

OCA at 06:39, 16 October 2019

OCA — Wed, 16 Oct 2019 06:39:28 GMT

←Older revision		Revision as of 06:39, 16 October 2019
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	==Crystal structure of an A-DNA dodecamer containing 5-bromouracil==		==Crystal structure of an A-DNA dodecamer containing 5-bromouracil==
-	<StructureSection load='5mvl' size='340' side='right' caption='[[5mvl]], [[Resolution\|resolution]] 1.41Å' scene=''>	+	<StructureSection load='5mvl' size='340' side='right'caption='[[5mvl]], [[Resolution\|resolution]] 1.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5mvl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MVL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MVL FirstGlance]. <br>		<table><tr><td colspan='2'>[[5mvl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MVL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MVL FirstGlance]. <br>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Brown, T]]		[[Category: Brown, T]]
	[[Category: Hardwick, J S]]		[[Category: Hardwick, J S]]

OCA at 07:20, 24 May 2017

OCA — Wed, 24 May 2017 07:20:22 GMT

←Older revision		Revision as of 07:20, 24 May 2017
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mvl OCA], [http://pdbe.org/5mvl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mvl RCSB], [http://www.ebi.ac.uk/pdbsum/5mvl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mvl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mvl OCA], [http://pdbe.org/5mvl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mvl RCSB], [http://www.ebi.ac.uk/pdbsum/5mvl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mvl ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The mechanism by which the recently identified DNA modification 5-formylcytosine (fC) is recognized by epigenetic writer and reader proteins is not known. Recently, an unusual DNA structure, F-DNA, has been proposed as the basis for enzyme recognition of clusters of fC. We used NMR and X-ray crystallography to compare several modified DNA duplexes with unmodified analogs and found that in the crystal state the duplexes all belong to the A family, whereas in solution they are all members of the B family. We found that, contrary to previous findings, fC does not significantly affect the structure of DNA, although there are modest local differences at the modification sites. Hence, global conformation changes are unlikely to account for the recognition of this modified base, and our structural data favor a mechanism that operates at base-pair resolution for the recognition of fC by epigenome-modifying enzymes.
		+
		+	5-Formylcytosine does not change the global structure of DNA.,Hardwick JS, Ptchelkine D, El-Sagheer AH, Tear I, Singleton D, Phillips SEV, Lane AN, Brown T Nat Struct Mol Biol. 2017 May 15. doi: 10.1038/nsmb.3411. PMID:28504696<ref>PMID:28504696</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5mvl" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 12:59, 10 May 2017

OCA — Wed, 10 May 2017 12:59:36 GMT

←Older revision		Revision as of 12:59, 10 May 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5mvl is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of an A-DNA dodecamer containing 5-bromouracil==
-		+	<StructureSection load='5mvl' size='340' side='right' caption='[[5mvl]], [[Resolution\|resolution]] 1.41Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5mvl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MVL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MVL FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mvl OCA], [http://pdbe.org/5mvl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mvl RCSB], [http://www.ebi.ac.uk/pdbsum/5mvl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mvl ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Brown, T]]
		+	[[Category: Hardwick, J S]]
		+	[[Category: Phillips, S E.V]]
		+	[[Category: Ptchelkine, D]]
		+	[[Category: 5-bromouracil]]
		+	[[Category: A-dna]]
		+	[[Category: Cpg]]
		+	[[Category: Dna]]

OCA at 11:41, 9 March 2017

OCA — Thu, 09 Mar 2017 11:41:59 GMT

←Older revision		Revision as of 11:41, 9 March 2017
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5mvl is ON HOLD	+	The entry 5mvl is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5mvl" [edit=sysop:move=sysop]

OCA — Wed, 25 Jan 2017 20:38:09 GMT

Protected "5mvl" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:38, 25 January 2017

OCA: New page: '''Unreleased structure''' The entry 5mvl is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 25 Jan 2017 20:38:08 GMT

New page: '''Unreleased structure''' The entry 5mvl is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5mvl is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]