5nce - Revision history

OCA at 10:21, 14 June 2023

OCA — Wed, 14 Jun 2023 10:21:15 GMT

←Older revision		Revision as of 10:21, 14 June 2023
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	==Structure of PsDef1 defensin from Pinus sylvestris==		==Structure of PsDef1 defensin from Pinus sylvestris==
-	<StructureSection load='5nce' size='340' side='right' caption='[[5nce~~]], [[NMR_Ensembles_of_Models \| 15 NMR models~~]]' scene=''>	+	<StructureSection load='5nce' size='340' side='right'caption='[[5nce]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nce]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Pinsy Pinsy~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5NCE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nce]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pinus_sylvestris Pinus sylvestris]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NCE FirstGlance]. <br>
-	</td></tr>~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Def1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3349 PINSY])</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nce OCA], [https://pdbe.org/5nce PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nce RCSB], [https://www.ebi.ac.uk/pdbsum/5nce PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nce ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5nce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nce OCA], [~~http~~://pdbe.org/5nce PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5nce RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5nce PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5nce ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/DEF1_PINSY DEF1_PINSY]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 5nce" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5nce" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Defensin 3D structures\|Defensin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pinsy~~]]	+	[[Category: Large Structures]]
-	[[Category: Bessolitsyna~~, E K~~]]	+	[[Category: Pinus sylvestris]]
-	[[Category: Ermakova~~, E A~~]]	+	[[Category: Bessolitsyna EK]]
-	[[Category: Khairutdinov~~, B I~~]]	+	[[Category: Ermakova EA]]
-	[[Category: Kovaleva, V]]	+	[[Category: Khairutdinov BI]]
-	[[Category: Nesmelova~~, I V~~]]	+	[[Category: Kovaleva V]]
-	[[Category: Tarasova~~, N B~~]]	+	[[Category: Nesmelova IV]]
-	[[Category: Toporkova~~, Y Y~~]]	+	[[Category: Tarasova NB]]
-	[[Category: Zuev~~, Y F]]~~	+	[[Category: Toporkova YY]]
-	~~[[Category: Amylase inhibition]]~~	+	[[Category: Zuev YF]]
-	~~[[Category: Antibacterial activity]]~~	+
-	~~[[Category: Conformational dynamic]]~~	+
-	~~[[Category: Defensin]]~~	+
-	~~[[Category: Plant defensin]]~~	+
-	~~[[Category: Plant protein]]~~	+
-	~~[[Category: Scotts pine defensin~~]]	+

OCA at 08:23, 2 May 2018

OCA — Wed, 02 May 2018 08:23:22 GMT

←Older revision		Revision as of 08:23, 2 May 2018
Line 3:		Line 3:
	<StructureSection load='5nce' size='340' side='right' caption='[[5nce]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>		<StructureSection load='5nce' size='340' side='right' caption='[[5nce]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nce]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NCE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nce]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pinsy Pinsy]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NCE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nce OCA], [http://pdbe.org/5nce PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nce RCSB], [http://www.ebi.ac.uk/pdbsum/5nce PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nce ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Def1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3349 PINSY])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nce OCA], [http://pdbe.org/5nce PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nce RCSB], [http://www.ebi.ac.uk/pdbsum/5nce PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nce ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Pinsy]]
	[[Category: Bessolitsyna, E K]]		[[Category: Bessolitsyna, E K]]
	[[Category: Ermakova, E A]]		[[Category: Ermakova, E A]]

OCA at 11:16, 3 August 2017

OCA — Thu, 03 Aug 2017 11:16:52 GMT

←Older revision		Revision as of 11:16, 3 August 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5nce is ~~ON HOLD~~	+	==Structure of PsDef1 defensin from Pinus sylvestris==
		+	<StructureSection load='5nce' size='340' side='right' caption='[[5nce]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5nce]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NCE FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nce OCA], [http://pdbe.org/5nce PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nce RCSB], [http://www.ebi.ac.uk/pdbsum/5nce PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nce ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Plants have developed a complex defense response system against pests and pathogens. Defensins, produced by plants as part of their innate immune response, form the family of small, basic, cysteine-rich proteins with activity primarily directed against fungal pathogens. In addition, plant defensins can show antibacterial activity and protease and insect amylase inhibitory activities. However, in gymnosperms, only antifungal activity of defensins has been described thus far. Here, we report antibacterial and insect alpha-amylase inhibition activities for defensin PsDef1 from P. sylvestris, the first defensin from gymnosperms with a broad range of biological activities described. We also report the solution NMR structure of PsDef1 and its dynamics properties assessed by a combination of experimental NMR and computational techniques. Collectively, our data provide an insight into structure, dynamics, and functional properties of PsDef1 that could be common between defensins from this taxonomic group.

-	~~Authors: Khairutdinov~~, ~~B.I.~~, ~~Ermakova, E.A~~., ~~Bessolitsyna~~, ~~E.K.~~, ~~Toporkova~~, ~~Y.Y.~~, Tarasova, ~~N.B.~~, Kovaleva, V., Zuev, Y.F., ~~Nesmelova, I~~.V.	+	NMR structure, conformational dynamics, and biological activity of PsDef1 defensin from Pinus sylvestris.,Khairutdinov BI, Ermakova EA, Yusypovych YM, Bessolicina EK, Tarasova NB, Toporkova YY, Kovaleva V, Zuev YF, Nesmelova IV Biochim Biophys Acta. 2017 Aug;1865(8):1085-1094. doi:, 10.1016/j.bbapap.2017.05.012. Epub 2017 May 17. PMID:28528214<ref>PMID:28528214</ref>

-	~~Description: Structure~~ of ~~PsDef1 defensin from Pinus sylvestris~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category~~: ~~Nesmelova, I.V]]~~	+	<div class="pdbe-citations 5nce" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Toporkova~~, ~~Y.Y~~]]	+	== References ==
-	[[Category: ~~Zuev~~, ~~Y.F~~]]	+	<references/>
-	[[Category: ~~Ermakova~~, ~~E.A~~]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Bessolitsyna, E K]]
		+	[[Category: Ermakova, E A]]
		+	[[Category: Khairutdinov, B I]]
	[[Category: Kovaleva, V]]		[[Category: Kovaleva, V]]
-	[[Category: ~~Khairutdinov~~, B.I]]	+	[[Category: Nesmelova, I V]]
-	[[Category: ~~Bessolitsyna~~, ~~E.K~~]]	+	[[Category: Tarasova, N B]]
-	[[Category: ~~Tarasova~~, ~~N.B~~]]	+	[[Category: Toporkova, Y Y]]
		+	[[Category: Zuev, Y F]]
		+	[[Category: Amylase inhibition]]
		+	[[Category: Antibacterial activity]]
		+	[[Category: Conformational dynamic]]
		+	[[Category: Defensin]]
		+	[[Category: Plant defensin]]
		+	[[Category: Plant protein]]
		+	[[Category: Scotts pine defensin]]

OCA at 09:53, 5 April 2017

OCA — Wed, 05 Apr 2017 09:53:38 GMT

←Older revision		Revision as of 09:53, 5 April 2017
Line 3:		Line 3:
	The entry 5nce is ON HOLD		The entry 5nce is ON HOLD

-	Authors: Khairutdinov, B.I., Ermakova, E.A., ~~Bessolicina~~, E.K., Toporkova, Y.Y., Tarasova, N.B., Kovaleva, V., Zuev, Y.F., Nesmelova, I.V.	+	Authors: Khairutdinov, B.I., Ermakova, E.A., Bessolitsyna, E.K., Toporkova, Y.Y., Tarasova, N.B., Kovaleva, V., Zuev, Y.F., Nesmelova, I.V.

	Description: Structure of PsDef1 defensin from Pinus sylvestris		Description: Structure of PsDef1 defensin from Pinus sylvestris
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	[[Category: Kovaleva, V]]		[[Category: Kovaleva, V]]
	[[Category: Khairutdinov, B.I]]		[[Category: Khairutdinov, B.I]]
		+	[[Category: Bessolitsyna, E.K]]
	[[Category: Tarasova, N.B]]		[[Category: Tarasova, N.B]]
-	[[Category: Bessolicina, E.K]]

OCA: Protected "5nce" [edit=sysop:move=sysop]

OCA — Wed, 15 Mar 2017 17:23:14 GMT

Protected "5nce" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:23, 15 March 2017

OCA: New page: '''Unreleased structure''' The entry 5nce is ON HOLD Authors: Khairutdinov, B.I., Ermakova, E.A., Bessolicina, E.K., Toporkova, Y.Y., Tarasova, N.B., Kovaleva, V., Zuev, Y.F., Nesmelova...

OCA — Wed, 15 Mar 2017 17:23:12 GMT

New page: '''Unreleased structure''' The entry 5nce is ON HOLD Authors: Khairutdinov, B.I., Ermakova, E.A., Bessolicina, E.K., Toporkova, Y.Y., Tarasova, N.B., Kovaleva, V., Zuev, Y.F., Nesmelova...

New page

'''Unreleased structure'''

The entry 5nce is ON HOLD

Authors: Khairutdinov, B.I., Ermakova, E.A., Bessolicina, E.K., Toporkova, Y.Y., Tarasova, N.B., Kovaleva, V., Zuev, Y.F., Nesmelova, I.V.

Description: Structure of PsDef1 defensin from Pinus sylvestris
[[Category: Unreleased Structures]]
[[Category: Nesmelova, I.V]]
[[Category: Toporkova, Y.Y]]
[[Category: Zuev, Y.F]]
[[Category: Ermakova, E.A]]
[[Category: Kovaleva, V]]
[[Category: Khairutdinov, B.I]]
[[Category: Tarasova, N.B]]
[[Category: Bessolicina, E.K]]