5nck - Revision history

OCA at 12:46, 15 November 2023

OCA — Wed, 15 Nov 2023 12:46:36 GMT

←Older revision		Revision as of 12:46, 15 November 2023
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	<StructureSection load='5nck' size='340' side='right'caption='[[5nck]], [[Resolution\|resolution]] 2.23Å' scene=''>		<StructureSection load='5nck' size='340' side='right'caption='[[5nck]], [[Resolution\|resolution]] 2.23Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nck]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5NCK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nck]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusobacterium_nucleatum Fusobacterium nucleatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NCK FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>FN1474 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~851~~ "~~Bacillus fusiformis~~" ~~Veillon and Zuber 1898])</td~~>~~</tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.23Å</td></tr>
-	~~<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N~~-~~acylmannosamine_kinase N-acylmannosamine kinase]~~, ~~with EC number~~ [~~http://www.brenda-enzymes.info/php/result_flat.php4?ecno=~~2.~~7.1.60 2.7.1.60] </span>~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nck OCA], [https://pdbe.org/5nck PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nck RCSB], [https://www.ebi.ac.uk/pdbsum/5nck PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nck ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5nck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nck OCA], [~~http~~://pdbe.org/5nck PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5nck RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5nck PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5nck ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8RDN7_FUSNN Q8RDN7_FUSNN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus fusiformis veillon and zuber 1898~~]]	+	[[Category: Fusobacterium nucleatum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: N-acylmannosamine kinase]]~~	+	[[Category: Caing-Carlsson R]]
-	[[Category: Caing-Carlsson, R]]	+	[[Category: Friemann R]]
-	[[Category: Friemann, R]]	+	[[Category: Ramaswamy S]]
-	[[Category: Ramaswamy, S]]	+	[[Category: Sharma A]]
-	[[Category: Sharma, A]]	+
-	~~[[Category: N-acetylmannosamine kinase]]~~	+
-	~~[[Category: Rok family]]~~	+
-	~~[[Category: Sialic acid]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Zinc-binding motif~~]]	+

OCA at 06:43, 16 October 2019

OCA — Wed, 16 Oct 2019 06:43:24 GMT

←Older revision		Revision as of 06:43, 16 October 2019
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	==The Crystal Structure of N-acetylmannosamine kinase in Fusobacterium nucleatum==		==The Crystal Structure of N-acetylmannosamine kinase in Fusobacterium nucleatum==
-	<StructureSection load='5nck' size='340' side='right' caption='[[5nck]], [[Resolution\|resolution]] 2.23Å' scene=''>	+	<StructureSection load='5nck' size='340' side='right'caption='[[5nck]], [[Resolution\|resolution]] 2.23Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5nck]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NCK FirstGlance]. <br>		<table><tr><td colspan='2'>[[5nck]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NCK FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus fusiformis veillon and zuber 1898]]		[[Category: Bacillus fusiformis veillon and zuber 1898]]
		+	[[Category: Large Structures]]
	[[Category: N-acylmannosamine kinase]]		[[Category: N-acylmannosamine kinase]]
	[[Category: Caing-Carlsson, R]]		[[Category: Caing-Carlsson, R]]

OCA at 11:06, 6 November 2017

OCA — Mon, 06 Nov 2017 11:06:09 GMT

←Older revision		Revision as of 11:06, 6 November 2017
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-	'''Unreleased structure'''

-	The ~~entry~~ 5nck is ~~ON HOLD~~	+	==The Crystal Structure of N-acetylmannosamine kinase in Fusobacterium nucleatum==
		+	<StructureSection load='5nck' size='340' side='right' caption='[[5nck]], [[Resolution\|resolution]] 2.23Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5nck]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NCK FirstGlance]. <br>
		+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FN1474 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=851 "Bacillus fusiformis" Veillon and Zuber 1898])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acylmannosamine_kinase N-acylmannosamine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.60 2.7.1.60] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nck OCA], [http://pdbe.org/5nck PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nck RCSB], [http://www.ebi.ac.uk/pdbsum/5nck PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nck ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Sialic acids comprise a varied group of nine-carbon amino sugars that are widely distributed among mammals and higher metazoans. Some human commensals and bacterial pathogens can scavenge sialic acids from their environment and degrade them for use as a carbon and nitrogen source. The enzyme N-acetylmannosamine kinase (NanK; EC 2.7.1.60) belongs to the transcriptional repressors, uncharacterized open reading frames and sugar kinases (ROK) superfamily. NanK catalyzes the second step of the sialic acid catabolic pathway, transferring a phosphate group from adenosine 5'-triphosphate to the C6 position of N-acetylmannosamine to generate N-acetylmannosamine 6-phosphate. The structure of NanK from Fusobacterium nucleatum was determined to 2.23 A resolution by X-ray crystallography. Unlike other NanK enzymes and ROK family members, F. nucleatum NanK does not have a conserved zinc-binding site. In spite of the absence of the zinc-binding site, all of the major structural features of enzymatic activity are conserved.

-	~~Authors:~~ Caing-Carlsson, R., ~~Sharma~~, A., ~~Friemann~~, R., Ramaswamy, S.	+	Crystal structure of N-acetylmannosamine kinase from Fusobacterium nucleatum.,Caing-Carlsson R, Goyal P, Sharma A, Ghosh S, Setty TG, North RA, Friemann R, Ramaswamy S Acta Crystallogr F Struct Biol Commun. 2017 Jun 1;73(Pt 6):356-362. doi:, 10.1107/S2053230X17007439. Epub 2017 May 31. PMID:28580924<ref>PMID:28580924</ref>

-	~~Description: The Crystal Structure~~ of N-~~acetylmannosamine kinase in Fusobacterium nucleatum~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
-	[[Category: ~~Ramaswamy, S~~]]	+	<div class="pdbe-citations 5nck" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bacillus fusiformis veillon and zuber 1898]]
		+	[[Category: N-acylmannosamine kinase]]
	[[Category: Caing-Carlsson, R]]		[[Category: Caing-Carlsson, R]]
	[[Category: Friemann, R]]		[[Category: Friemann, R]]
		+	[[Category: Ramaswamy, S]]
	[[Category: Sharma, A]]		[[Category: Sharma, A]]
		+	[[Category: N-acetylmannosamine kinase]]
		+	[[Category: Rok family]]
		+	[[Category: Sialic acid]]
		+	[[Category: Transferase]]
		+	[[Category: Zinc-binding motif]]

OCA: Protected "5nck" [edit=sysop:move=sysop]

OCA — Wed, 15 Mar 2017 17:23:54 GMT

Protected "5nck" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:23, 15 March 2017

OCA: New page: '''Unreleased structure''' The entry 5nck is ON HOLD Authors: Caing-Carlsson, R., Sharma, A., Friemann, R., Ramaswamy, S. Description: The Crystal Structure of N-acetylmannosamine kina...

OCA — Wed, 15 Mar 2017 17:23:52 GMT

New page: '''Unreleased structure''' The entry 5nck is ON HOLD Authors: Caing-Carlsson, R., Sharma, A., Friemann, R., Ramaswamy, S. Description: The Crystal Structure of N-acetylmannosamine kina...

New page

'''Unreleased structure'''

The entry 5nck is ON HOLD

Authors: Caing-Carlsson, R., Sharma, A., Friemann, R., Ramaswamy, S.

Description: The Crystal Structure of N-acetylmannosamine kinase in Fusobacterium nucleatum
[[Category: Unreleased Structures]]
[[Category: Ramaswamy, S]]
[[Category: Caing-Carlsson, R]]
[[Category: Friemann, R]]
[[Category: Sharma, A]]