5ndz - Revision history

OCA at 12:49, 15 November 2023

OCA — Wed, 15 Nov 2023 12:49:42 GMT

←Older revision		Revision as of 12:49, 15 November 2023
Line 3:		Line 3:
	<StructureSection load='5ndz' size='340' side='right'caption='[[5ndz]], [[Resolution\|resolution]] 3.60Å' scene=''>		<StructureSection load='5ndz' size='340' side='right'caption='[[5ndz]], [[Resolution\|resolution]] 3.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ndz]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NDZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5NDZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ndz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NDZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NDZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8UN:2-(6-BROMANYL-1,3-BENZODIOXOL-5-YL)-~{N}-(4-CYANOPHENYL)-1-[(1~{S})-1-CYCLOHEXYLETHYL]BENZIMIDAZOLE-5-CARBOXAMIDE'>8UN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.6Å</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">F2RL1, GPR11, PAR2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8UN:2-(6-BROMANYL-1,3-BENZODIOXOL-5-YL)-~{N}-(4-CYANOPHENYL)-1-[(1~{S})-1-CYCLOHEXYLETHYL]BENZIMIDAZOLE-5-CARBOXAMIDE'>8UN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ndz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ndz OCA], [https://pdbe.org/5ndz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ndz RCSB], [https://www.ebi.ac.uk/pdbsum/5ndz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ndz ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5ndz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ndz OCA], [~~http~~://pdbe.org/5ndz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5ndz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5ndz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5ndz ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/PAR2_HUMAN PAR2_HUMAN] Receptor for trypsin and trypsin-like enzymes coupled to G proteins. Its function is mediated through the activation of several signaling pathways including phospholipase C (PLC), intracellular calcium, mitogen-activated protein kinase (MAPK), I-kappaB kinase/NF-kappaB and Rho. Can also be transactivated by cleaved F2R/PAR1. Involved in modulation of inflammatory responses and regulation of innate and adaptive immunity, and acts as a sensor for proteolytic enzymes generated during infection. Generally is promoting inflammation. Can signal synergistically with TLR4 and probably TLR2 in inflammatory responses and modulates TLR3 signaling. Has a protective role in establishing the endothelial barrier; the activity involves coagulation factor X. Proposed to have a bronchoprotective role in airway epithelium, but also shown to compromise the airway epithelial barrier by interrupting E-cadherin adhesion. Involved in the regulation of vascular tone; activation results in hypotension presumably mediated by vasodilation. Associates with a subset of G proteins alpha subunits such as G alpha-q, G alpha-11, G alpha-14, G alpha-12 and G alpha-13, but probably not with G(o) alpha, G(i) subunit alpha-1 and G(i) subunit alpha-2. However, according to PubMed:21627585 can signal through G(i) subunit alpha. Believed to be a class B receptor which internalizes as a complex with arrestin and traffic with it to endosomal vesicles, presumably as desensitized receptor, for extended periods of time. Mediates inhibition of TNF-alpha stimulated JNK phosphorylation via coupling to G alpha-q/11; the function involves dissociation of RIPK1 and TRADD from TNFR1. Mediates phosphorylation of nuclear factor NF-kappa-B RELA subunit at 'Ser-536'; the function involves IKBKB and is predominantly independent of G proteins. Involved in cellular migration. Involved in cytoskeletal rearrangement and chemotaxis through beta-arrestin-promoted scaffolds; the function is independent of G alpha-q/11 and involves promotion of cofilin dephosphoryltaion and actin filament severing. Induces redistribution of COPS5 from the plasma membrane to the cytosol and activation of the JNK cascade is mediated by COPS5. Involved in the recruitment of leukocytes to the sites of inflammation and is the major PAR receptor capable of modulating eosinophil function such as proinflammatory cytokine secretion, superoxide production and degranulation. During inflammation promotes dendritic cell maturation, trafficking to the lymph nodes and subsequent T-cell activation. Involved in antimicrobial response of innate immnune cells; activation enhances phagocytosis of Gram-positive and killing of Gram-negative bacteria. Acts synergistically with interferon-gamma in enhancing antiviral responses. Implicated in a number of acute and chronic inflammatory diseases such as of the joints, lungs, brain, gastrointestinal tract, periodontium, skin, and vascular systems, and in autoimmune disorders.<ref>PMID:10086357</ref> <ref>PMID:10725339</ref> <ref>PMID:11413129</ref> <ref>PMID:11441110</ref> <ref>PMID:11447194</ref> <ref>PMID:11714832</ref> <ref>PMID:12832443</ref> <ref>PMID:15155775</ref> <ref>PMID:16359518</ref> <ref>PMID:16410250</ref> <ref>PMID:16478888</ref> <ref>PMID:16714334</ref> <ref>PMID:17404307</ref> <ref>PMID:17500066</ref> <ref>PMID:18424071</ref> <ref>PMID:18453611</ref> <ref>PMID:18474671</ref> <ref>PMID:18622013</ref> <ref>PMID:19494303</ref> <ref>PMID:19781631</ref> <ref>PMID:19864598</ref> <ref>PMID:19865078</ref> <ref>PMID:20826780</ref> <ref>PMID:21501162</ref> [https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
		+	[[Category: Escherichia virus T4]]
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Lysozyme]]~~	+	[[Category: Aggeler B]]
-	[[Category: Aggeler, B]]	+	[[Category: Brown DG]]
-	[[Category: Brown~~, D G~~]]	+	[[Category: Brown G]]
-	[[Category: Brown, G]]	+	[[Category: Cheng RKY]]
-	[[Category: Cheng~~, R K.Y~~]]	+	[[Category: Cooke RM]]
-	[[Category: Cooke~~, R M~~]]	+	[[Category: Dekker N]]
-	[[Category: Dekker, N]]	+	[[Category: Dore AS]]
-	[[Category: Dore~~, A S~~]]	+	[[Category: Dumelin CE]]
-	[[Category: Dumelin~~, C E~~]]	+	[[Category: Edman K]]
-	[[Category: Edman, K]]	+	[[Category: Fiez-Vandal C]]
-	[[Category: Fiez-Vandal, C]]	+	[[Category: Geschwindner S]]
-	[[Category: Geschwindner, S]]	+	[[Category: Grebner C]]
-	[[Category: Grebner, C]]	+	[[Category: Hermansson N-O]]
-	[[Category: Hermansson, N O]]	+	[[Category: Jazayeri A]]
-	[[Category: Jazayeri, A]]	+	[[Category: Johansson P]]
-	[[Category: Johansson, P]]	+	[[Category: Leong L]]
-	[[Category: Leong, L]]	+	[[Category: Marshall FH]]
-	[[Category: Marshall~~, F H~~]]	+	[[Category: Prihandoko R]]
-	[[Category: Prihandoko, R]]	+	[[Category: Rappas M]]
-	[[Category: Rappas, M]]	+	[[Category: Schlenker O]]
-	[[Category: Schlenker, O]]	+	[[Category: Snijder A]]
-	[[Category: Snijder, A]]	+	[[Category: Soutter H]]
-	[[Category: Soutter, H]]	+	[[Category: Sundstrom L]]
-	[[Category: Sundstrom, L]]	+	[[Category: Tehan B]]
-	[[Category: Tehan, B]]	+	[[Category: Thornton P]]
-	[[Category: Thornton, P]]	+	[[Category: Troast D]]
-	[[Category: Troast, D]]	+	[[Category: Wiggin G]]
-	[[Category: Wiggin, G]]	+	[[Category: Zhukov A]]
-	[[Category: Zhukov, A]]	+
-	~~[[Category: Gpcr]]~~	+
-	~~[[Category: Membrane protein~~]]	+

OCA at 12:03, 26 August 2020

OCA — Wed, 26 Aug 2020 12:03:08 GMT

←Older revision		Revision as of 12:03, 26 August 2020
Line 1:		Line 1:

	==Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with AZ3451 at 3.6 angstrom resolution==		==Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with AZ3451 at 3.6 angstrom resolution==
-	<StructureSection load='5ndz' size='340' side='right' caption='[[5ndz]], [[Resolution\|resolution]] 3.60Å' scene=''>	+	<StructureSection load='5ndz' size='340' side='right'caption='[[5ndz]], [[Resolution\|resolution]] 3.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ndz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NDZ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5NDZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ndz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NDZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5NDZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8UN:2-(6-BROMANYL-1,3-BENZODIOXOL-5-YL)-~{N}-(4-CYANOPHENYL)-1-[(1~{S})-1-CYCLOHEXYLETHYL]BENZIMIDAZOLE-5-CARBOXAMIDE'>8UN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8UN:2-(6-BROMANYL-1,3-BENZODIOXOL-5-YL)-~{N}-(4-CYANOPHENYL)-1-[(1~{S})-1-CYCLOHEXYLETHYL]BENZIMIDAZOLE-5-CARBOXAMIDE'>8UN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">F2RL1, GPR11, PAR2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ndz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ndz OCA], [http://pdbe.org/5ndz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ndz RCSB], [http://www.ebi.ac.uk/pdbsum/5ndz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ndz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ndz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ndz OCA], [http://pdbe.org/5ndz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ndz RCSB], [http://www.ebi.ac.uk/pdbsum/5ndz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ndz ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 5ndz" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5ndz" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Aggeler, B]]		[[Category: Aggeler, B]]

OCA at 13:01, 4 May 2017

OCA — Thu, 04 May 2017 13:01:57 GMT

←Older revision		Revision as of 13:01, 4 May 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5ndz is ~~ON HOLD~~	+	==Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with AZ3451 at 3.6 angstrom resolution==
		+	<StructureSection load='5ndz' size='340' side='right' caption='[[5ndz]], [[Resolution\|resolution]] 3.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5ndz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NDZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NDZ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8UN:2-(6-BROMANYL-1,3-BENZODIOXOL-5-YL)-~{N}-(4-CYANOPHENYL)-1-[(1~{S})-1-CYCLOHEXYLETHYL]BENZIMIDAZOLE-5-CARBOXAMIDE'>8UN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ndz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ndz OCA], [http://pdbe.org/5ndz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ndz RCSB], [http://www.ebi.ac.uk/pdbsum/5ndz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ndz ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protease-activated receptors (PARs) are a family of G-protein-coupled receptors (GPCRs) that are irreversibly activated by proteolytic cleavage of the N terminus, which unmasks a tethered peptide ligand that binds and activates the transmembrane receptor domain, eliciting a cellular cascade in response to inflammatory signals and other stimuli. PARs are implicated in a wide range of diseases, such as cancer and inflammation. PARs have been the subject of major pharmaceutical research efforts but the discovery of small-molecule antagonists that effectively bind them has proved challenging. The only marketed drug targeting a PAR is vorapaxar, a selective antagonist of PAR1 used to prevent thrombosis. The structure of PAR1 in complex with vorapaxar has been reported previously. Despite sequence homology across the PAR isoforms, discovery of PAR2 antagonists has been less successful, although GB88 has been described as a weak antagonist. Here we report crystal structures of PAR2 in complex with two distinct antagonists and a blocking antibody. The antagonist AZ8838 binds in a fully occluded pocket near the extracellular surface. Functional and binding studies reveal that AZ8838 exhibits slow binding kinetics, which is an attractive feature for a PAR2 antagonist competing against a tethered ligand. Antagonist AZ3451 binds to a remote allosteric site outside the helical bundle. We propose that antagonist binding prevents structural rearrangements required for receptor activation and signalling. We also show that a blocking antibody antigen-binding fragment binds to the extracellular surface of PAR2, preventing access of the tethered ligand to the peptide-binding site. These structures provide a basis for the development of selective PAR2 antagonists for a range of therapeutic uses.

-	~~Authors~~:	+	Structural insight into allosteric modulation of protease-activated receptor 2.,Cheng RKY, Fiez-Vandal C, Schlenker O, Edman K, Aggeler B, Brown DG, Brown GA, Cooke RM, Dumelin CE, Dore AS, Geschwindner S, Grebner C, Hermansson NO, Jazayeri A, Johansson P, Leong L, Prihandoko R, Rappas M, Soutter H, Snijder A, Sundstrom L, Tehan B, Thornton P, Troast D, Wiggin G, Zhukov A, Marshall FH, Dekker N Nature. 2017 Apr 26. doi: 10.1038/nature22309. PMID:28445455<ref>PMID:28445455</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5ndz" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Lysozyme]]
		+	[[Category: Aggeler, B]]
		+	[[Category: Brown, D G]]
		+	[[Category: Brown, G]]
		+	[[Category: Cheng, R K.Y]]
		+	[[Category: Cooke, R M]]
		+	[[Category: Dekker, N]]
		+	[[Category: Dore, A S]]
		+	[[Category: Dumelin, C E]]
		+	[[Category: Edman, K]]
		+	[[Category: Fiez-Vandal, C]]
		+	[[Category: Geschwindner, S]]
		+	[[Category: Grebner, C]]
		+	[[Category: Hermansson, N O]]
		+	[[Category: Jazayeri, A]]
		+	[[Category: Johansson, P]]
		+	[[Category: Leong, L]]
		+	[[Category: Marshall, F H]]
		+	[[Category: Prihandoko, R]]
		+	[[Category: Rappas, M]]
		+	[[Category: Schlenker, O]]
		+	[[Category: Snijder, A]]
		+	[[Category: Soutter, H]]
		+	[[Category: Sundstrom, L]]
		+	[[Category: Tehan, B]]
		+	[[Category: Thornton, P]]
		+	[[Category: Troast, D]]
		+	[[Category: Wiggin, G]]
		+	[[Category: Zhukov, A]]
		+	[[Category: Gpcr]]
		+	[[Category: Membrane protein]]

OCA: Protected "5ndz" [edit=sysop:move=sysop]

OCA — Wed, 15 Mar 2017 17:28:24 GMT

Protected "5ndz" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:28, 15 March 2017

OCA: New page: '''Unreleased structure''' The entry 5ndz is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 15 Mar 2017 17:28:23 GMT

New page: '''Unreleased structure''' The entry 5ndz is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5ndz is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]