5nen - Revision history

OCA at 12:51, 15 November 2023

OCA — Wed, 15 Nov 2023 12:51:32 GMT

←Older revision		Revision as of 12:51, 15 November 2023
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	<StructureSection load='5nen' size='340' side='right'caption='[[5nen]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='5nen' size='340' side='right'caption='[[5nen]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nen]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_marcescens"_(bizio_1823)_trevisan_in_de_toni_and_trevisan_1889 "bacillus~~ marcescens~~" (bizio 1823) trevisan in de toni and trevisan 1889~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NEN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5NEN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nen]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NEN FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>lipC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~615~~ "~~Bacillus marcescens~~" ~~(Bizio 1823) Trevisan in de Toni and Trevisan 1889~~])</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.901Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5nen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nen OCA], [~~http~~://pdbe.org/5nen PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5nen RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5nen PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5nen ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nen OCA], [https://pdbe.org/5nen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nen RCSB], [https://www.ebi.ac.uk/pdbsum/5nen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nen ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q54457_SERMA Q54457_SERMA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	==See Also==		==See Also==
-	*[[Lipase\|Lipase]]	+	*[[Lipase 3D Structures\|Lipase 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Akutsu, M~~]]	+	[[Category: Serratia marcescens]]
-	[[Category: ~~Murata, D~~]]	+	[[Category: Akutsu M]]
-	[[Category: ~~Takano, K~~]]	+	[[Category: Murata D]]
-	[[Category: ~~Hydrolase]]~~	+	[[Category: Takano K]]
-	~~[[Category: Lipase~~]]	+

OCA at 06:43, 16 October 2019

OCA — Wed, 16 Oct 2019 06:43:54 GMT

←Older revision		Revision as of 06:43, 16 October 2019
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	==Crystal structure of the soluble domain of LipC, a membrane fusion protein of a type I secretion system==		==Crystal structure of the soluble domain of LipC, a membrane fusion protein of a type I secretion system==
-	<StructureSection load='5nen' size='340' side='right' caption='[[5nen]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='5nen' size='340' side='right'caption='[[5nen]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5nen]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_marcescens"_(bizio_1823)_trevisan_in_de_toni_and_trevisan_1889 "bacillus marcescens" (bizio 1823) trevisan in de toni and trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NEN FirstGlance]. <br>		<table><tr><td colspan='2'>[[5nen]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_marcescens"_(bizio_1823)_trevisan_in_de_toni_and_trevisan_1889 "bacillus marcescens" (bizio 1823) trevisan in de toni and trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NEN FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 5nen" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5nen" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Lipase\|Lipase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Akutsu, M]]		[[Category: Akutsu, M]]
	[[Category: Murata, D]]		[[Category: Murata, D]]

OCA at 07:42, 6 December 2017

OCA — Wed, 06 Dec 2017 07:42:02 GMT

←Older revision		Revision as of 07:42, 6 December 2017
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	<StructureSection load='5nen' size='340' side='right' caption='[[5nen]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='5nen' size='340' side='right' caption='[[5nen]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nen]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NEN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nen]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_marcescens"_(bizio_1823)_trevisan_in_de_toni_and_trevisan_1889 "bacillus marcescens" (bizio 1823) trevisan in de toni and trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NEN FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nen OCA], [http://pdbe.org/5nen PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nen RCSB], [http://www.ebi.ac.uk/pdbsum/5nen PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nen ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lipC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=615 "Bacillus marcescens" (Bizio 1823) Trevisan in de Toni and Trevisan 1889])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nen OCA], [http://pdbe.org/5nen PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nen RCSB], [http://www.ebi.ac.uk/pdbsum/5nen PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nen ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:38, 22 November 2017

OCA — Wed, 22 Nov 2017 07:38:07 GMT

←Older revision		Revision as of 07:38, 22 November 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5nen is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of the soluble domain of LipC, a membrane fusion protein of a type I secretion system==
		+	<StructureSection load='5nen' size='340' side='right' caption='[[5nen]], [[Resolution\|resolution]] 2.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5nen]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NEN FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nen OCA], [http://pdbe.org/5nen PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nen RCSB], [http://www.ebi.ac.uk/pdbsum/5nen PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nen ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Serratia marcescens secretes a lipase, LipA, through a type I secretion system (T1SS). The T1SS for LipA, the Lip system, is composed of an inner membrane ABC transporter with its nucleotide-binding domains (NBD), LipB, a membrane fusion protein, LipC, and an outer membrane channel protein, LipD. Passenger protein secreted by this system has been functionally and structurally characterized well, but relatively little information about the transporter complex is available. Here, we report the crystallographic studies of LipC without the membrane anchor region, LipC-, and the NBD of LipB (LipB-NBD). LipC- crystallographic analysis has led to the determination of the structure of the long alpha-helical and lipoyl domains, but not the area where it interacts with LipB, suggesting that the region is flexible without LipB. The long alpha-helical domain has three alpha-helices, which interacts with LipD in the periplasm. LipB-NBD has the common overall architecture and ATP hydrolysis activity of ABC transporter NBDs. Using the predicted models of full-length LipB and LipD, the overall structural insight into the Lip system is discussed.

-	~~Authors~~: ~~Murata~~, D., ~~Akutsu~~, M., ~~Takano~~, K.	+	Structural Basis for the Serratia marcescens Lipase Secretion System: Crystal Structures of the Membrane Fusion Protein and Nucleotide-Binding Domain.,Murata D, Okano H, Angkawidjaja C, Akutsu M, Tanaka SI, Kitahara K, Yoshizawa T, Matsumura H, Kado Y, Mizohata E, Inoue T, Sano S, Koga Y, Kanaya S, Takano K Biochemistry. 2017 Nov 10. doi: 10.1021/acs.biochem.7b00985. PMID:29094929<ref>PMID:29094929</ref>

-	~~Description: Crystal structure of the soluble domain of LipC~~, a ~~membrane fusion protein~~ of ~~a type I secretion system~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 5nen" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Akutsu, M]]		[[Category: Akutsu, M]]
-	[[Category: Takano, K]]
	[[Category: Murata, D]]		[[Category: Murata, D]]
		+	[[Category: Takano, K]]
		+	[[Category: Hydrolase]]
		+	[[Category: Lipase]]

OCA: Protected "5nen" [edit=sysop:move=sysop]

OCA — Wed, 05 Apr 2017 09:57:42 GMT

Protected "5nen" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:57, 5 April 2017

OCA: New page: '''Unreleased structure''' The entry 5nen is ON HOLD until Paper Publication Authors: Murata, D., Akutsu, M., Takano, K. Description: Crystal structure of the soluble domain of LipC, a...

OCA — Wed, 05 Apr 2017 09:57:41 GMT

New page: '''Unreleased structure''' The entry 5nen is ON HOLD until Paper Publication Authors: Murata, D., Akutsu, M., Takano, K. Description: Crystal structure of the soluble domain of LipC, a...

New page

'''Unreleased structure'''

The entry 5nen is ON HOLD until Paper Publication

Authors: Murata, D., Akutsu, M., Takano, K.

Description: Crystal structure of the soluble domain of LipC, a membrane fusion protein of a type I secretion system
[[Category: Unreleased Structures]]
[[Category: Akutsu, M]]
[[Category: Takano, K]]
[[Category: Murata, D]]