5nhe - Revision history

OCA at 07:27, 1 May 2024

OCA — Wed, 01 May 2024 07:27:20 GMT

←Older revision		Revision as of 07:27, 1 May 2024
Line 10:		Line 10:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/Q9P8C9_PIRSE Q9P8C9_PIRSE]		[https://www.uniprot.org/uniprot/Q9P8C9_PIRSE Q9P8C9_PIRSE]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Xylose isomerase from Piromyces sp. E2 (PirXI) can be used for equipping Saccharomyces cerevisiae with the capacity to ferment xylose to ethanol. The biochemical properties and structure of the enzyme have not been described even though its metal content, catalytic parameters and expression level are critical for rapid xylose utilization. We have isolated the enzyme after high-level expression in E. coli, analyzed the metal-dependence of its catalytic properties and solved twelve crystal structures in the presence of different metals, substrates, and substrate analogs. The activity assays revealed that various bivalent metals can activate PirXI for xylose isomerization. Among these metals, Mn2+ is the most favorable for catalytic activity. Furthermore, the enzyme shows the highest affinity for Mn2+ which was established by measuring the activation constants (Kact) for different metals. Metal analysis of the purified enzyme showed that in vivo the enzyme binds a mixture of metals which is determined by metal availability as well as the affinity, indicating that native metal composition can influence activity. The crystal structures show the presence of an active site similar to that of other xylose isomerases, with a D-xylose binding site containing two tryptophans and a catalytic histidine, as well as two metal binding sites that are formed by carboxylate groups of conserved aspartates and glutamates. The binding positions and conformations of the metal-coordinating residues varied slightly for different metals, which is hypothesized to contribute to the observed metal-dependence of the isomerase activity.
-
-	Metal-dependence of xylose isomerase from Piromyces sp. E2 explored by activity profiling and protein crystallography.,Lee M, Rozeboom HJ, de Waal P, de Jong R, Dudek HM, Janssen DB Biochemistry. 2017 Oct 18. doi: 10.1021/acs.biochem.7b00777. PMID:29045784<ref>PMID:29045784</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5nhe" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 12:58, 15 November 2023

OCA — Wed, 15 Nov 2023 12:58:00 GMT

←Older revision		Revision as of 12:58, 15 November 2023
Line 1:		Line 1:

	==Crystal structure of xylose isomerase from Piromyces E2 in complex with two Cd2+ ions and xylose==		==Crystal structure of xylose isomerase from Piromyces E2 in complex with two Cd2+ ions and xylose==
-	<StructureSection load='5nhe' size='340' side='right' caption='[[5nhe]], [[Resolution\|resolution]] 1.86Å' scene=''>	+	<StructureSection load='5nhe' size='340' side='right'caption='[[5nhe]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nhe]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Pirse Pirse~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NHE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5NHE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nhe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Piromyces_sp._E2 Piromyces sp. E2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NHE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NHE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XLS:D-XYLOSE+(LINEAR+FORM)'>XLS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.86Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5nh5\|5nh5]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XLS:D-XYLOSE+(LINEAR+FORM)'>XLS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">xylA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=73868 PIRSE])</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nhe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nhe OCA], [https://pdbe.org/5nhe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nhe RCSB], [https://www.ebi.ac.uk/pdbsum/5nhe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nhe ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xylose_isomerase Xylose isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.5 5.3.1.5] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5nhe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nhe OCA], [~~http~~://pdbe.org/5nhe PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5nhe RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5nhe PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5nhe ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9P8C9_PIRSE Q9P8C9_PIRSE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pirse~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Xylose isomerase~~]]	+	[[Category: Piromyces sp. E2]]
-	[[Category: Janssen~~, D B~~]]	+	[[Category: Janssen DB]]
-	[[Category: Rozeboom~~, H J]]~~	+	[[Category: Rozeboom HJ]]
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Tim-barrel~~]]	+

OCA at 07:47, 29 August 2018

OCA — Wed, 29 Aug 2018 07:47:47 GMT

←Older revision		Revision as of 07:47, 29 August 2018
Line 5:		Line 5:
	<table><tr><td colspan='2'>[[5nhe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pirse Pirse]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NHE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NHE FirstGlance]. <br>		<table><tr><td colspan='2'>[[5nhe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pirse Pirse]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NHE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NHE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XLS:D-XYLOSE+(LINEAR+FORM)'>XLS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XLS:D-XYLOSE+(LINEAR+FORM)'>XLS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[~~d_1200004044~~\|~~d_1200004044~~]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5nh5\|5nh5]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">xylA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=73868 PIRSE])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">xylA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=73868 PIRSE])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xylose_isomerase Xylose isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.5 5.3.1.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xylose_isomerase Xylose isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.5 5.3.1.5] </span></td></tr>

OCA at 10:11, 15 November 2017

OCA — Wed, 15 Nov 2017 10:11:17 GMT

←Older revision		Revision as of 10:11, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='5nhe' size='340' side='right' caption='[[5nhe]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='5nhe' size='340' side='right' caption='[[5nhe]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nhe]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NHE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NHE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nhe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pirse Pirse]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NHE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NHE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XLS:D-XYLOSE+(LINEAR+FORM)'>XLS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XLS:D-XYLOSE+(LINEAR+FORM)'>XLS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[d_1200004044\|d_1200004044]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[d_1200004044\|d_1200004044]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">xylA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=73868 PIRSE])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xylose_isomerase Xylose isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.5 5.3.1.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xylose_isomerase Xylose isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.5 5.3.1.5] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nhe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nhe OCA], [http://pdbe.org/5nhe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nhe RCSB], [http://www.ebi.ac.uk/pdbsum/5nhe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nhe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nhe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nhe OCA], [http://pdbe.org/5nhe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nhe RCSB], [http://www.ebi.ac.uk/pdbsum/5nhe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nhe ProSAT]</span></td></tr>
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Pirse]]
	[[Category: Xylose isomerase]]		[[Category: Xylose isomerase]]
	[[Category: Janssen, D B]]		[[Category: Janssen, D B]]

OCA at 06:12, 1 November 2017

OCA — Wed, 01 Nov 2017 06:12:52 GMT

←Older revision		Revision as of 06:12, 1 November 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5nhe is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of xylose isomerase from Piromyces E2 in complex with two Cd2+ ions and xylose==
		+	<StructureSection load='5nhe' size='340' side='right' caption='[[5nhe]], [[Resolution\|resolution]] 1.86Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5nhe]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NHE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NHE FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XLS:D-XYLOSE+(LINEAR+FORM)'>XLS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[d_1200004044\|d_1200004044]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xylose_isomerase Xylose isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.5 5.3.1.5] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nhe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nhe OCA], [http://pdbe.org/5nhe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nhe RCSB], [http://www.ebi.ac.uk/pdbsum/5nhe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nhe ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Xylose isomerase from Piromyces sp. E2 (PirXI) can be used for equipping Saccharomyces cerevisiae with the capacity to ferment xylose to ethanol. The biochemical properties and structure of the enzyme have not been described even though its metal content, catalytic parameters and expression level are critical for rapid xylose utilization. We have isolated the enzyme after high-level expression in E. coli, analyzed the metal-dependence of its catalytic properties and solved twelve crystal structures in the presence of different metals, substrates, and substrate analogs. The activity assays revealed that various bivalent metals can activate PirXI for xylose isomerization. Among these metals, Mn2+ is the most favorable for catalytic activity. Furthermore, the enzyme shows the highest affinity for Mn2+ which was established by measuring the activation constants (Kact) for different metals. Metal analysis of the purified enzyme showed that in vivo the enzyme binds a mixture of metals which is determined by metal availability as well as the affinity, indicating that native metal composition can influence activity. The crystal structures show the presence of an active site similar to that of other xylose isomerases, with a D-xylose binding site containing two tryptophans and a catalytic histidine, as well as two metal binding sites that are formed by carboxylate groups of conserved aspartates and glutamates. The binding positions and conformations of the metal-coordinating residues varied slightly for different metals, which is hypothesized to contribute to the observed metal-dependence of the isomerase activity.

-	~~Authors: Rozeboom, H~~.J., ~~Janssen~~, D.B.	+	Metal-dependence of xylose isomerase from Piromyces sp. E2 explored by activity profiling and protein crystallography.,Lee M, Rozeboom HJ, de Waal P, de Jong R, Dudek HM, Janssen DB Biochemistry. 2017 Oct 18. doi: 10.1021/acs.biochem.7b00777. PMID:29045784<ref>PMID:29045784</ref>

-	~~Description: Crystal structure~~ of ~~xylose isomerase from Piromyces E2 in complex with two Cd2+ ions and xylose~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
-	[[Category: Janssen, D.B]]	+	<div class="pdbe-citations 5nhe" style="background-color:#fffaf0;"></div>
-	[[Category: Rozeboom, H.J]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Xylose isomerase]]
		+	[[Category: Janssen, D B]]
		+	[[Category: Rozeboom, H J]]
		+	[[Category: Isomerase]]
		+	[[Category: Tim-barrel]]

OCA at 10:32, 27 April 2017

OCA — Thu, 27 Apr 2017 10:32:23 GMT

←Older revision		Revision as of 10:32, 27 April 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5nhe is ON HOLD	+	The entry 5nhe is ON HOLD until Paper Publication

	Authors: Rozeboom, H.J., Janssen, D.B.		Authors: Rozeboom, H.J., Janssen, D.B.

OCA: Protected "5nhe" [edit=sysop:move=sysop]

OCA — Wed, 05 Apr 2017 10:08:14 GMT

Protected "5nhe" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:08, 5 April 2017

OCA: New page: '''Unreleased structure''' The entry 5nhe is ON HOLD Authors: Rozeboom, H.J., Janssen, D.B. Description: Crystal structure of xylose isomerase from Piromyces E2 in complex with two Cd2...

OCA — Wed, 05 Apr 2017 10:08:13 GMT

New page: '''Unreleased structure''' The entry 5nhe is ON HOLD Authors: Rozeboom, H.J., Janssen, D.B. Description: Crystal structure of xylose isomerase from Piromyces E2 in complex with two Cd2...

New page

'''Unreleased structure'''

The entry 5nhe is ON HOLD

Authors: Rozeboom, H.J., Janssen, D.B.

Description: Crystal structure of xylose isomerase from Piromyces E2 in complex with two Cd2+ ions and xylose
[[Category: Unreleased Structures]]
[[Category: Janssen, D.B]]
[[Category: Rozeboom, H.J]]