5npq - Revision history

OCA at 13:20, 15 November 2023

OCA — Wed, 15 Nov 2023 13:20:29 GMT

←Older revision		Revision as of 13:20, 15 November 2023
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	==Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound==		==Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound==
-	<StructureSection load='5npq' size='340' side='right' caption='[[5npq]], [[Resolution\|resolution]] 2.37Å' scene=''>	+	<StructureSection load='5npq' size='340' side='right'caption='[[5npq]], [[Resolution\|resolution]] 2.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5npq]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5NPQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5npq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NPQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=94Q:~{S}-[2-[3-[[(2~{S})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl]+9-(3-but-3-ynyl-1,2-diazirin-3-yl)nonanethioate'>94Q</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.372Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c2y\|4c2y]], [[4c2z\|4c2z]], [[5mu6\|5mu6]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=94Q:~{S}-[2-[3-[[(2~{S})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl]+9-(3-but-3-ynyl-1,2-diazirin-3-yl)nonanethioate'>94Q</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NMT1, NMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5npq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npq OCA], [https://pdbe.org/5npq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5npq RCSB], [https://www.ebi.ac.uk/pdbsum/5npq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5npq ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5npq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npq OCA], [~~http~~://pdbe.org/5npq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5npq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5npq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5npq ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/NMT1_HUMAN NMT1_HUMAN]] Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.	+	[https://www.uniprot.org/uniprot/NMT1_HUMAN NMT1_HUMAN] Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Glycylpeptide N-tetradecanoyltransferase~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Human~~]]	+	[[Category: Large Structures]]
-	[[Category: Fedoryshchak, R]]	+	[[Category: Fedoryshchak R]]
-	[[Category: Perez-Dorado, I]]	+	[[Category: Perez-Dorado I]]
-	[[Category: Shen, M]]	+	[[Category: Shen M]]
-	[[Category: Tate~~, E W]]~~	+	[[Category: Tate EW]]
-	~~[[Category: Chemical probe]]~~	+
-	~~[[Category: Myristol-coa analogue]]~~	+
-	~~[[Category: N-myristoylation]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Uv active~~]]	+

OCA at 06:10, 6 June 2018

OCA — Wed, 06 Jun 2018 06:10:58 GMT

←Older revision		Revision as of 06:10, 6 June 2018
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	<StructureSection load='5npq' size='340' side='right' caption='[[5npq]], [[Resolution\|resolution]] 2.37Å' scene=''>		<StructureSection load='5npq' size='340' side='right' caption='[[5npq]], [[Resolution\|resolution]] 2.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5npq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NPQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5npq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NPQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=94Q:~{S}-[2-[3-[[(2~{S})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl]+9-(3-but-3-ynyl-1,2-diazirin-3-yl)nonanethioate'>94Q</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=94Q:~{S}-[2-[3-[[(2~{S})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl]+9-(3-but-3-ynyl-1,2-diazirin-3-yl)nonanethioate'>94Q</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c2y\|4c2y]], [[4c2z\|4c2z]], [[5mu6\|5mu6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c2y\|4c2y]], [[4c2z\|4c2z]], [[5mu6\|5mu6]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NMT1, NMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5npq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npq OCA], [http://pdbe.org/5npq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5npq RCSB], [http://www.ebi.ac.uk/pdbsum/5npq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5npq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5npq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npq OCA], [http://pdbe.org/5npq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5npq RCSB], [http://www.ebi.ac.uk/pdbsum/5npq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5npq ProSAT]</span></td></tr>
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	</StructureSection>		</StructureSection>
	[[Category: Glycylpeptide N-tetradecanoyltransferase]]		[[Category: Glycylpeptide N-tetradecanoyltransferase]]
		+	[[Category: Human]]
	[[Category: Fedoryshchak, R]]		[[Category: Fedoryshchak, R]]
	[[Category: Perez-Dorado, I]]		[[Category: Perez-Dorado, I]]

OCA at 05:23, 30 May 2018

OCA — Wed, 30 May 2018 05:23:43 GMT

←Older revision		Revision as of 05:23, 30 May 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5npq is ~~ON HOLD~~	+	==Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound==
-		+	<StructureSection load='5npq' size='340' side='right' caption='[[5npq]], [[Resolution\|resolution]] 2.37Å' scene=''>
-	~~Authors~~: ~~Shen~~, M., ~~Perez~~-~~Dorado~~, I., ~~Fedoryshchak~~, R., ~~Tate~~, E.W.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5npq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NPQ FirstGlance]. <br>
-	~~Description: Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=94Q:~{S}-[2-[3-[[(2~{S})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl]+9-(3-but-3-ynyl-1,2-diazirin-3-yl)nonanethioate'>94Q</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c2y\|4c2y]], [[4c2z\|4c2z]], [[5mu6\|5mu6]]</td></tr>
-	[[Category: ~~Shen, M~~]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5npq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npq OCA], [http://pdbe.org/5npq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5npq RCSB], [http://www.ebi.ac.uk/pdbsum/5npq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5npq ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NMT1_HUMAN NMT1_HUMAN]] Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Glycylpeptide N-tetradecanoyltransferase]]
	[[Category: Fedoryshchak, R]]		[[Category: Fedoryshchak, R]]
-	[[Category: Tate, E.W]]
	[[Category: Perez-Dorado, I]]		[[Category: Perez-Dorado, I]]
		+	[[Category: Shen, M]]
		+	[[Category: Tate, E W]]
		+	[[Category: Chemical probe]]
		+	[[Category: Myristol-coa analogue]]
		+	[[Category: N-myristoylation]]
		+	[[Category: Transferase]]
		+	[[Category: Uv active]]

OCA: Protected "5npq" [edit=sysop:move=sysop]

OCA — Thu, 27 Apr 2017 10:45:35 GMT

Protected "5npq" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:45, 27 April 2017

OCA: New page: '''Unreleased structure''' The entry 5npq is ON HOLD Authors: Shen, M., Perez-Dorado, I., Fedoryshchak, R., Tate, E.W. Description: Human N-myristoyltransferase 1 (MNT1) with Myristoyl...

OCA — Thu, 27 Apr 2017 10:45:34 GMT

New page: '''Unreleased structure''' The entry 5npq is ON HOLD Authors: Shen, M., Perez-Dorado, I., Fedoryshchak, R., Tate, E.W. Description: Human N-myristoyltransferase 1 (MNT1) with Myristoyl...

New page

'''Unreleased structure'''

The entry 5npq is ON HOLD

Authors: Shen, M., Perez-Dorado, I., Fedoryshchak, R., Tate, E.W.

Description: Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound
[[Category: Unreleased Structures]]
[[Category: Shen, M]]
[[Category: Fedoryshchak, R]]
[[Category: Tate, E.W]]
[[Category: Perez-Dorado, I]]