5npy - Revision history

OCA at 13:21, 15 November 2023

OCA — Wed, 15 Nov 2023 13:21:03 GMT

←Older revision		Revision as of 13:21, 15 November 2023
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	==Crystal structure of Helicobacter pylori flagellar hook protein FlgE2==		==Crystal structure of Helicobacter pylori flagellar hook protein FlgE2==
-	<StructureSection load='5npy' size='340' side='right' caption='[[5npy]], [[Resolution\|resolution]] 2.29Å' scene=''>	+	<StructureSection load='5npy' size='340' side='right'caption='[[5npy]], [[Resolution\|resolution]] 2.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5npy]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Helpg Helpg~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5NPY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5npy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_G27 Helicobacter pylori G27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NPY FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=144:TRIS~~-~~HYDROXYMETHYL-METHYL-AMMONIUM'>144</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.292Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~flgE-2, HPG27_859 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=563041 HELPG])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=144:TRIS-HYDROXYMETHYL-METHYL-AMMONIUM'>144</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5npy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npy OCA], [~~http~~://pdbe.org/5npy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5npy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5npy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5npy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5npy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npy OCA], [https://pdbe.org/5npy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5npy RCSB], [https://www.ebi.ac.uk/pdbsum/5npy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5npy ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B5Z7R4_HELPG B5Z7R4_HELPG]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Helpg~~]]	+	[[Category: Helicobacter pylori G27]]
-	[[Category: Kekez, I]]	+	[[Category: Large Structures]]
-	[[Category: Loconte, V]]	+	[[Category: Kekez I]]
-	[[Category: Matkovic-Calogovic, D]]	+	[[Category: Loconte V]]
-	[[Category: Zanotti, G]]	+	[[Category: Matkovic-Calogovic D]]
-	~~[[Category: Flagellum]]~~	+	[[Category: Zanotti G]]
-	~~[[Category: Helicobactyer pylori]]~~	+
-	~~[[Category: Hook]]~~	+
-	~~[[Category: Motor protein~~]]	+

OCA at 08:51, 27 December 2017

OCA — Wed, 27 Dec 2017 08:51:58 GMT

←Older revision		Revision as of 08:51, 27 December 2017
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	<StructureSection load='5npy' size='340' side='right' caption='[[5npy]], [[Resolution\|resolution]] 2.29Å' scene=''>		<StructureSection load='5npy' size='340' side='right' caption='[[5npy]], [[Resolution\|resolution]] 2.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5npy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NPY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5npy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helpg Helpg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NPY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=144:TRIS-HYDROXYMETHYL-METHYL-AMMONIUM'>144</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=144:TRIS-HYDROXYMETHYL-METHYL-AMMONIUM'>144</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">flgE-2, HPG27_859 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=563041 HELPG])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5npy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npy OCA], [http://pdbe.org/5npy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5npy RCSB], [http://www.ebi.ac.uk/pdbsum/5npy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5npy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5npy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npy OCA], [http://pdbe.org/5npy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5npy RCSB], [http://www.ebi.ac.uk/pdbsum/5npy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5npy ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Helpg]]
	[[Category: Kekez, I]]		[[Category: Kekez, I]]
	[[Category: Loconte, V]]		[[Category: Loconte, V]]

OCA at 07:28, 15 November 2017

OCA — Wed, 15 Nov 2017 07:28:27 GMT

←Older revision		Revision as of 07:28, 15 November 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5npy is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of Helicobacter pylori flagellar hook protein FlgE2==
		+	<StructureSection load='5npy' size='340' side='right' caption='[[5npy]], [[Resolution\|resolution]] 2.29Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5npy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NPY FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=144:TRIS-HYDROXYMETHYL-METHYL-AMMONIUM'>144</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5npy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npy OCA], [http://pdbe.org/5npy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5npy RCSB], [http://www.ebi.ac.uk/pdbsum/5npy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5npy ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Helicobacter pylori flagellum is a complex rotatory nano-machine fundamental for bacterium survival in the human stomach. Protein FlgE is a component of the hook, a flexible junction exposed on the cell surface. In H. pylori genome two different genes are present in different positions coding for hypothetical FlgE. The first protein, FlgE1, is the actual component of the flagellum hook, whilst the second, FlgE2, shares only 26% of sequence identity with the other and its physiological function is still undefined. We have cloned, purified and crystallized FlgE2, whose structure, determined by the SAD method, shows that the overall structural organization of the protein is composed of three distinct domains, two of them relatively similar to that of other FlgE from other Gram-negative bacteria, whilst the third is quite peculiar to H. pylori. The crystal structure, along with the detected interaction with the regulatory cap protein FlgD, suggests a complementary function of FlgE1 and FlgE2 in H. pylori flagellum, possibly typical of polar flagella, confirming the role of both proteins in the flagellar hook organization. Although some general features are shared with other Gram-negative bacteria, the presence of two different hook proteins implicates that the molecular organization of H. pylori flagellum has its own peculiarities. This article is protected by copyright. All rights reserved.

-	~~Authors: Loconte~~, V~~., Zanotti, G.~~, Kekez, I., Matkovic-Calogovic, D.	+	Structural characterization of FlgE2 protein from Helicobacter pylori hook.,Loconte V, Kekez I, Matkovic-Calogovic D, Zanotti G FEBS J. 2017 Oct 30. doi: 10.1111/febs.14312. PMID:29083539<ref>PMID:29083539</ref>

-	~~Description: Crystal structure~~ of ~~Helicobacter pylori flagellar hook protein FlgE2~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category~~: ~~Loconte, V]]~~	+	<div class="pdbe-citations 5npy" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Kekez, I]]		[[Category: Kekez, I]]
-	[[Category: ~~Zanotti~~, G]]	+	[[Category: Loconte, V]]
	[[Category: Matkovic-Calogovic, D]]		[[Category: Matkovic-Calogovic, D]]
		+	[[Category: Zanotti, G]]
		+	[[Category: Flagellum]]
		+	[[Category: Helicobactyer pylori]]
		+	[[Category: Hook]]
		+	[[Category: Motor protein]]

OCA at 09:34, 4 May 2017

OCA — Thu, 04 May 2017 09:34:17 GMT

←Older revision		Revision as of 09:34, 4 May 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5npy is ON HOLD	+	The entry 5npy is ON HOLD until Paper Publication

	Authors: Loconte, V., Zanotti, G., Kekez, I., Matkovic-Calogovic, D.		Authors: Loconte, V., Zanotti, G., Kekez, I., Matkovic-Calogovic, D.

OCA: Protected "5npy" [edit=sysop:move=sysop]

OCA — Thu, 27 Apr 2017 10:46:23 GMT

Protected "5npy" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:46, 27 April 2017

OCA: New page: '''Unreleased structure''' The entry 5npy is ON HOLD Authors: Loconte, V., Zanotti, G., Kekez, I., Matkovic-Calogovic, D. Description: Crystal structure of Helicobacter pylori flagella...

OCA — Thu, 27 Apr 2017 10:46:22 GMT

New page: '''Unreleased structure''' The entry 5npy is ON HOLD Authors: Loconte, V., Zanotti, G., Kekez, I., Matkovic-Calogovic, D. Description: Crystal structure of Helicobacter pylori flagella...

New page

'''Unreleased structure'''

The entry 5npy is ON HOLD

Authors: Loconte, V., Zanotti, G., Kekez, I., Matkovic-Calogovic, D.

Description: Crystal structure of Helicobacter pylori flagellar hook protein FlgE2
[[Category: Unreleased Structures]]
[[Category: Loconte, V]]
[[Category: Kekez, I]]
[[Category: Zanotti, G]]
[[Category: Matkovic-Calogovic, D]]