5nxd - Revision history

OCA at 12:14, 22 November 2023

OCA — Wed, 22 Nov 2023 12:14:24 GMT

←Older revision		Revision as of 12:14, 22 November 2023
Line 3:		Line 3:
	<StructureSection load='5nxd' size='340' side='right'caption='[[5nxd]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='5nxd' size='340' side='right'caption='[[5nxd]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nxd]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5NXD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nxd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NXD FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=9D8:4~~-[~~(3-CHLOROPHENYL)SULFAMOYL~~]~~-~{N}-(PHENYLMETHYL)-~{N}-PROPYL-BENZAMIDE'>9D8</scene>, <scene name='pdbligand=EDO:~~1~~,2-ETHANEDIOL'>EDO</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>LIMK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~9606 HUMAN])</td~~><~~/tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9D8:4-[(3-CHLOROPHENYL)SULFAMOYL]-~{N}-(PHENYLMETHYL)-~{N}-PROPYL-BENZAMIDE'>9D8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[http~~:~~//en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase]~~, ~~with EC number [http://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]~~ </~~span~~></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nxd OCA], [https://pdbe.org/5nxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nxd RCSB], [https://www.ebi.ac.uk/pdbsum/5nxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nxd ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5nxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nxd OCA], [~~http~~://pdbe.org/5nxd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5nxd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5nxd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5nxd ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/LIMK2_HUMAN LIMK2_HUMAN]] Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.<ref>PMID:10436159</ref> <ref>PMID:11018042</ref>	+	[https://www.uniprot.org/uniprot/LIMK2_HUMAN LIMK2_HUMAN] Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.<ref>PMID:10436159</ref> <ref>PMID:11018042</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Non-specific serine/threonine protein kinase]]~~	+	[[Category: Arrowsmith CH]]
-	[[Category: Arrowsmith~~, C H~~]]	+	[[Category: Bountra C]]
-	[[Category: Bountra, C]]	+	[[Category: Bullock AN]]
-	[[Category: Bullock~~, A N~~]]	+	[[Category: Burgess-Brown N]]
-	[[Category: Burgess-Brown, N]]	+	[[Category: Edwards AM]]
-	~~[[Category: Delft, F von~~]]	+	[[Category: Hanke T]]
-	[[Category: Edwards~~, A M~~]]	+	[[Category: Knapp S]]
-	[[Category: Hanke, T]]	+	[[Category: Mathea S]]
-	[[Category: Knapp, S]]	+	[[Category: Newman JA]]
-	[[Category: Mathea, S]]	+	[[Category: Oerum S]]
-	[[Category: Newman~~, J A~~]]	+	[[Category: Salah E]]
-	[[Category: Oerum, S]]	+	[[Category: Wang D]]
-	[[Category: Salah, E]]	+	[[Category: Von Delft F]]
-	[[Category: Wang, D]]	+
-	[[Category: ~~Kinase actin cytoskeleton inhibitor dfg-out]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 12:13, 26 August 2020

OCA — Wed, 26 Aug 2020 12:13:44 GMT

←Older revision		Revision as of 12:13, 26 August 2020
Line 1:		Line 1:

	==LIM Domain Kinase 2 (LIMK2) In Complex With TH-300==		==LIM Domain Kinase 2 (LIMK2) In Complex With TH-300==
-	<StructureSection load='5nxd' size='340' side='right' caption='[[5nxd]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='5nxd' size='340' side='right'caption='[[5nxd]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nxd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXD OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5NXD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nxd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5NXD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9D8:4-[(3-CHLOROPHENYL)SULFAMOYL]-~{N}-(PHENYLMETHYL)-~{N}-PROPYL-BENZAMIDE'>9D8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9D8:4-[(3-CHLOROPHENYL)SULFAMOYL]-~{N}-(PHENYLMETHYL)-~{N}-PROPYL-BENZAMIDE'>9D8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LIMK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5nxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nxd OCA], [http://pdbe.org/5nxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nxd RCSB], [http://www.ebi.ac.uk/pdbsum/5nxd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nxd ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5nxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nxd OCA], [http://pdbe.org/5nxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nxd RCSB], [http://www.ebi.ac.uk/pdbsum/5nxd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nxd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]

OCA at 13:47, 24 May 2017

OCA — Wed, 24 May 2017 13:47:30 GMT

←Older revision		Revision as of 13:47, 24 May 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5nxd ~~is ON HOLD~~	+	==LIM Domain Kinase 2 (LIMK2) In Complex With TH-300==
-		+	<StructureSection load='5nxd' size='340' side='right' caption='[[5nxd]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~Authors~~: ~~Mathea, S~~.~~, Salah, E~~.~~, Hanke, T~~.~~, Newman, J~~.A.~~, Oerum, S~~.~~, Wang, D~~.~~, Burgess~~-~~Brown, N~~.~~, von Delft, F~~., ~~Arrowsmith~~, C.H., ~~Edwards~~, A.M., ~~Bountra~~, C., ~~Bullock, A~~.N., ~~Knapp, S~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5nxd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NXD FirstGlance]. <br>
-	~~Description~~: ~~LIM Domain Kinase 2~~ (~~LIMK2~~)~~In Complex With TH-300~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9D8:4-[(3-CHLOROPHENYL)SULFAMOYL]-~{N}-(PHENYLMETHYL)-~{N}-PROPYL-BENZAMIDE'>9D8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-	[[Category: ~~Oerum~~, S]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nxd OCA], [http://pdbe.org/5nxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nxd RCSB], [http://www.ebi.ac.uk/pdbsum/5nxd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nxd ProSAT]</span></td></tr>
-	[[Category: ~~Mathea~~, S]]	+	</table>
-	[[Category: ~~Arrowsmith~~, ~~C.H~~]]	+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LIMK2_HUMAN LIMK2_HUMAN]] Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.<ref>PMID:10436159</ref> <ref>PMID:11018042</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Non-specific serine/threonine protein kinase]]
		+	[[Category: Arrowsmith, C H]]
		+	[[Category: Bountra, C]]
		+	[[Category: Bullock, A N]]
	[[Category: Burgess-Brown, N]]		[[Category: Burgess-Brown, N]]
-	[[Category: ~~Wang~~, D]]	+	[[Category: Delft, F von]]
-	[[Category: ~~Von Delft~~, F]]	+	[[Category: Edwards, A M]]
-	[[Category: ~~Bullock~~, ~~A.N~~]]	+	[[Category: Hanke, T]]
	[[Category: Knapp, S]]		[[Category: Knapp, S]]
-	[[Category: ~~Hanke~~, T]]	+	[[Category: Mathea, S]]
-	[[Category: ~~Edwards~~, A.M]]	+	[[Category: Newman, J A]]
-	[[Category: ~~Newman~~, ~~J.A~~]]	+	[[Category: Oerum, S]]
	[[Category: Salah, E]]		[[Category: Salah, E]]
-	[[Category: ~~Bountra~~, C]]	+	[[Category: Wang, D]]
		+	[[Category: Kinase actin cytoskeleton inhibitor dfg-out]]
		+	[[Category: Transferase]]

OCA: Protected "5nxd" [edit=sysop:move=sysop]

OCA — Wed, 17 May 2017 12:23:39 GMT

Protected "5nxd" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:23, 17 May 2017

OCA: New page: '''Unreleased structure''' The entry 5nxd is ON HOLD Authors: Mathea, S., Salah, E., Hanke, T., Newman, J.A., Oerum, S., Wang, D., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Ed...

OCA — Wed, 17 May 2017 12:23:37 GMT

New page: '''Unreleased structure''' The entry 5nxd is ON HOLD Authors: Mathea, S., Salah, E., Hanke, T., Newman, J.A., Oerum, S., Wang, D., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Ed...

New page

'''Unreleased structure'''

The entry 5nxd is ON HOLD

Authors: Mathea, S., Salah, E., Hanke, T., Newman, J.A., Oerum, S., Wang, D., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N., Knapp, S.

Description: LIM Domain Kinase 2 (LIMK2)In Complex With TH-300
[[Category: Unreleased Structures]]
[[Category: Oerum, S]]
[[Category: Mathea, S]]
[[Category: Arrowsmith, C.H]]
[[Category: Burgess-Brown, N]]
[[Category: Wang, D]]
[[Category: Von Delft, F]]
[[Category: Bullock, A.N]]
[[Category: Knapp, S]]
[[Category: Hanke, T]]
[[Category: Edwards, A.M]]
[[Category: Newman, J.A]]
[[Category: Salah, E]]
[[Category: Bountra, C]]