5nz1 - Revision history

OCA at 12:16, 22 November 2023

OCA — Wed, 22 Nov 2023 12:16:28 GMT

←Older revision		Revision as of 12:16, 22 November 2023
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	<StructureSection load='5nz1' size='340' side='right'caption='[[5nz1]], [[Resolution\|resolution]] 2.33Å' scene=''>		<StructureSection load='5nz1' size='340' side='right'caption='[[5nz1]], [[Resolution\|resolution]] 2.33Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nz1]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZ1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5NZ1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nz1]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NZ1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9EN:~{N}-[[(5~{S})-3-(3-fluoranyl-4-thiomorpholin-4-yl-phenyl)-2-oxidanylidene-1,3-oxazolidin-5-yl]methyl]ethanamide'>9EN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.33Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5nz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nz1 OCA], [~~http~~://pdbe.org/5nz1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5nz1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5nz1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5nz1 ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9EN:~{N}-[[(5~{S})-3-(3-fluoranyl-4-thiomorpholin-4-yl-phenyl)-2-oxidanylidene-1,3-oxazolidin-5-yl]methyl]ethanamide'>9EN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nz1 OCA], [https://pdbe.org/5nz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nz1 RCSB], [https://www.ebi.ac.uk/pdbsum/5nz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nz1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU]] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>	+	[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
		+
		+	==See Also==
		+	*[[Tetracycline repressor protein 3D structures\|Tetracycline repressor protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Blaszczyk, M~~]]	+	[[Category: Mycobacterium tuberculosis H37Rv]]
-	[[Category: ~~Blundell, T L~~]]	+	[[Category: Blaszczyk M]]
-	[[Category: ~~Mendes, V~~]]	+	[[Category: Blundell TL]]
-	[[Category: ~~Nikiforov, P O~~]]	+	[[Category: Mendes V]]
-	[[Category: ~~Boosting effect]]~~	+	[[Category: Nikiforov PO]]
-	~~[[Category: Ethr]]~~	+
-	~~[[Category: Represor]]~~	+
-	~~[[Category: Transcription~~]]	+

OCA at 12:14, 26 August 2020

OCA — Wed, 26 Aug 2020 12:14:35 GMT

←Older revision		Revision as of 12:14, 26 August 2020
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	==Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with sutezolid==		==Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with sutezolid==
-	<StructureSection load='5nz1' size='340' side='right' caption='[[5nz1]], [[Resolution\|resolution]] 2.33Å' scene=''>	+	<StructureSection load='5nz1' size='340' side='right'caption='[[5nz1]], [[Resolution\|resolution]] 2.33Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nz1]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5NZ1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nz1]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5NZ1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9EN:~{N}-[[(5~{S})-3-(3-fluoranyl-4-thiomorpholin-4-yl-phenyl)-2-oxidanylidene-1,3-oxazolidin-5-yl]methyl]ethanamide'>9EN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9EN:~{N}-[[(5~{S})-3-(3-fluoranyl-4-thiomorpholin-4-yl-phenyl)-2-oxidanylidene-1,3-oxazolidin-5-yl]methyl]ethanamide'>9EN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5nz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nz1 OCA], [http://pdbe.org/5nz1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nz1 RCSB], [http://www.ebi.ac.uk/pdbsum/5nz1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nz1 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5nz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nz1 OCA], [http://pdbe.org/5nz1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nz1 RCSB], [http://www.ebi.ac.uk/pdbsum/5nz1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nz1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Blaszczyk, M]]		[[Category: Blaszczyk, M]]
	[[Category: Blundell, T L]]		[[Category: Blundell, T L]]

OCA at 05:26, 30 May 2018

OCA — Wed, 30 May 2018 05:26:20 GMT

←Older revision		Revision as of 05:26, 30 May 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 5nz1 is ~~ON HOLD until Paper Publication~~	+	==Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with sutezolid==
-		+	<StructureSection load='5nz1' size='340' side='right' caption='[[5nz1]], [[Resolution\|resolution]] 2.33Å' scene=''>
-	~~Authors~~: ~~Mendes~~, V., ~~Blaszczyk, M~~., ~~Nikiforov~~, P.O., ~~Blundell, T~~.L.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5nz1]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NZ1 FirstGlance]. <br>
-	~~Description~~: ~~Structure of Transcriptional Regulatory Repressor Protein -EthR from Mycobacterium Tuberculosis~~ in ~~complex with sutezolid~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9EN:~{N}-[[(5~{S})-3-(3-fluoranyl-4-thiomorpholin-4-yl-phenyl)-2-oxidanylidene-1,3-oxazolidin-5-yl]methyl]ethanamide'>9EN</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nz1 OCA], [http://pdbe.org/5nz1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nz1 RCSB], [http://www.ebi.ac.uk/pdbsum/5nz1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nz1 ProSAT]</span></td></tr>
-	[[Category: Blundell, T.L]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU]] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Blaszczyk, M]]
		+	[[Category: Blundell, T L]]
	[[Category: Mendes, V]]		[[Category: Mendes, V]]
-	[[Category: ~~Blaszczyk~~, M]]	+	[[Category: Nikiforov, P O]]
-	[[Category: ~~Nikiforov, P.O~~]]	+	[[Category: Boosting effect]]
		+	[[Category: Ethr]]
		+	[[Category: Represor]]
		+	[[Category: Transcription]]

OCA: Protected "5nz1" [edit=sysop:move=sysop]

OCA — Wed, 24 May 2017 10:02:40 GMT

Protected "5nz1" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:02, 24 May 2017

OCA: New page: '''Unreleased structure''' The entry 5nz1 is ON HOLD until Paper Publication Authors: Mendes, V., Blaszczyk, M., Nikiforov, P.O., Blundell, T.L. Description: Structure of Transcription...

OCA — Wed, 24 May 2017 10:02:39 GMT

New page: '''Unreleased structure''' The entry 5nz1 is ON HOLD until Paper Publication Authors: Mendes, V., Blaszczyk, M., Nikiforov, P.O., Blundell, T.L. Description: Structure of Transcription...

New page

'''Unreleased structure'''

The entry 5nz1 is ON HOLD until Paper Publication

Authors: Mendes, V., Blaszczyk, M., Nikiforov, P.O., Blundell, T.L.

Description: Structure of Transcriptional Regulatory Repressor Protein -EthR from Mycobacterium Tuberculosis in complex with sutezolid
[[Category: Unreleased Structures]]
[[Category: Blundell, T.L]]
[[Category: Mendes, V]]
[[Category: Blaszczyk, M]]
[[Category: Nikiforov, P.O]]