5nzx - Revision history

OCA at 12:18, 22 November 2023

OCA — Wed, 22 Nov 2023 12:18:20 GMT

←Older revision		Revision as of 12:18, 22 November 2023
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	==Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)==		==Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)==
-	<StructureSection load='5nzx' size='340' side='right' caption='[[5nzx]], [[Resolution\|resolution]] 1.47Å' scene=''>	+	<StructureSection load='5nzx' size='340' side='right'caption='[[5nzx]], [[Resolution\|resolution]] 1.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5nzx]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5NZX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5nzx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NZX FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=9F2:Ceftriaxone'>9F2</scene~~>, ~~<scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.47Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~DCLRE1A, KIAA0086, SNM1, SNM1A ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=9606 HUMAN]~~)</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9F2:Ceftriaxone'>9F2</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5nzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nzx OCA], [~~http~~://pdbe.org/5nzx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5nzx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5nzx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5nzx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nzx OCA], [https://pdbe.org/5nzx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nzx RCSB], [https://www.ebi.ac.uk/pdbsum/5nzx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nzx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN]] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>	+	[https://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: Aitkenhead, H]]	+	[[Category: Large Structures]]
-	[[Category: Arrowsmith~~, C H~~]]	+	[[Category: Aitkenhead H]]
-	[[Category: Bountra, C]]	+	[[Category: Arrowsmith CH]]
-	[[Category: Burgess-Brown~~, N A]]~~	+	[[Category: Bountra C]]
-	~~[[Category: Delft, F von~~]]	+	[[Category: Burgess-Brown NA]]
-	[[Category: Edwards, A]]	+	[[Category: Edwards A]]
-	[[Category: Gileadi, O]]	+	[[Category: Gileadi O]]
-	[[Category: Krojer, T]]	+	[[Category: Krojer T]]
-	[[Category: Kupinska, K]]	+	[[Category: Kupinska K]]
-	[[Category: Newman~~, J A~~]]	+	[[Category: Newman JA]]
-	[[Category: Talon, R]]	+	[[Category: Talon R]]
-	[[Category: ~~Cephalosporin]]~~	+	[[Category: Von Delft F]]
-	~~[[Category: Cross-link repair]]~~	+
-	~~[[Category: Dclre1a]]~~	+
-	~~[[Category: Exonulcease]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 09:57, 16 November 2017

OCA — Thu, 16 Nov 2017 09:57:03 GMT

←Older revision		Revision as of 09:57, 16 November 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5nzx ~~is ON HOLD~~	+	==Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)==
-		+	<StructureSection load='5nzx' size='340' side='right' caption='[[5nzx]], [[Resolution\|resolution]] 1.47Å' scene=''>
-	~~Authors~~: ~~Newman, J~~.A., ~~Aitkenhead~~, H, ~~Kupinska~~, ~~K, Burgess~~-~~Brown~~, N.A., ~~Talon~~, R, ~~Krojer, T, von Delft, F~~, ~~Arrowsmith, C~~.H.~~, Edwards, A, Bountra, C, Gileadi, O~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5nzx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NZX FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of~~ DNA cross-link repair ~~protein 1A~~ in ~~complex with Ceftriaxone (alternative site)~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9F2:Ceftriaxone'>9F2</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DCLRE1A, KIAA0086, SNM1, SNM1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	[[Category: Aitkenhead, H, ~~Kupinska, K~~, Burgess-Brown, N.A]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nzx OCA], [http://pdbe.org/5nzx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nzx RCSB], [http://www.ebi.ac.uk/pdbsum/5nzx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nzx ProSAT]</span></td></tr>
-	[[Category: ~~Talon~~, R, Krojer, T, ~~Von Delft, F, Arrowsmith, C.H~~]]	+	</table>
-	[[Category: Newman, J.A]]	+	== Function ==
-	[[Category: ~~Edwards, A~~, ~~Bountra, C, Gileadi, O~~]]	+	[[http://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN]] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Aitkenhead, H]]
		+	[[Category: Arrowsmith, C H]]
		+	[[Category: Bountra, C]]
		+	[[Category: Burgess-Brown, N A]]
		+	[[Category: Delft, F von]]
		+	[[Category: Edwards, A]]
		+	[[Category: Gileadi, O]]
		+	[[Category: Krojer, T]]
		+	[[Category: Kupinska, K]]
		+	[[Category: Newman, J A]]
		+	[[Category: Talon, R]]
		+	[[Category: Cephalosporin]]
		+	[[Category: Cross-link repair]]
		+	[[Category: Dclre1a]]
		+	[[Category: Exonulcease]]
		+	[[Category: Hydrolase]]

OCA: Protected "5nzx" [edit=sysop:move=sysop]

OCA — Wed, 24 May 2017 10:04:34 GMT

Protected "5nzx" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:04, 24 May 2017

OCA: New page: '''Unreleased structure''' The entry 5nzx is ON HOLD Authors: Newman, J.A., Aitkenhead, H, Kupinska, K, Burgess-Brown, N.A., Talon, R, Krojer, T, von Delft, F, Arrowsmith, C.H., Edwards...

OCA — Wed, 24 May 2017 10:04:33 GMT

New page: '''Unreleased structure''' The entry 5nzx is ON HOLD Authors: Newman, J.A., Aitkenhead, H, Kupinska, K, Burgess-Brown, N.A., Talon, R, Krojer, T, von Delft, F, Arrowsmith, C.H., Edwards...

New page

'''Unreleased structure'''

The entry 5nzx is ON HOLD

Authors: Newman, J.A., Aitkenhead, H, Kupinska, K, Burgess-Brown, N.A., Talon, R, Krojer, T, von Delft, F, Arrowsmith, C.H., Edwards, A, Bountra, C, Gileadi, O

Description: Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)
[[Category: Unreleased Structures]]
[[Category: Aitkenhead, H, Kupinska, K, Burgess-Brown, N.A]]
[[Category: Talon, R, Krojer, T, Von Delft, F, Arrowsmith, C.H]]
[[Category: Newman, J.A]]
[[Category: Edwards, A, Bountra, C, Gileadi, O]]