5o37 - Revision history

OCA at 19:06, 29 November 2023

OCA — Wed, 29 Nov 2023 19:06:03 GMT

←Older revision		Revision as of 19:06, 29 November 2023
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	<StructureSection load='5o37' size='340' side='right'caption='[[5o37]], [[Resolution\|resolution]] 1.37Å' scene=''>		<StructureSection load='5o37' size='340' side='right'caption='[[5o37]], [[Resolution\|resolution]] 1.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5o37]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O37 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5O37 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5o37]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_stutzeri Pseudomonas stutzeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5O37 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GB:METHYLPHOSPHONIC+ACID+ESTER+GROUP'>GB</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.37Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5o37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o37 OCA], [~~http~~://pdbe.org/5o37 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5o37 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5o37 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5o37 ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GB:METHYLPHOSPHONIC+ACID+ESTER+GROUP'>GB</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5o37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o37 OCA], [https://pdbe.org/5o37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5o37 RCSB], [https://www.ebi.ac.uk/pdbsum/5o37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5o37 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PTXB_STUST PTXB_STUST]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bisson, C~~]]	+	[[Category: Pseudomonas stutzeri]]
-	[[Category: ~~Hitchcock, A~~]]	+	[[Category: Bisson C]]
-	[[Category: ~~Abc transporter]]~~	+	[[Category: Hitchcock A]]
-	~~[[Category: Marine bacteria]]~~	+
-	~~[[Category: Pbp]]~~	+
-	~~[[Category: Phosphite]]~~	+
-	~~[[Category: Sbp]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 12:16, 26 August 2020

OCA — Wed, 26 Aug 2020 12:16:49 GMT

←Older revision		Revision as of 12:16, 26 August 2020
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	==Pseudomonas stutzeri PtxB in complex with methylphosphonate (MPn) to 1.37 A resolution==		==Pseudomonas stutzeri PtxB in complex with methylphosphonate (MPn) to 1.37 A resolution==
-	<StructureSection load='5o37' size='340' side='right' caption='[[5o37]], [[Resolution\|resolution]] 1.37Å' scene=''>	+	<StructureSection load='5o37' size='340' side='right'caption='[[5o37]], [[Resolution\|resolution]] 1.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5o37]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O37 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5O37 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5o37]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O37 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5O37 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GB:METHYLPHOSPHONIC+ACID+ESTER+GROUP'>GB</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GB:METHYLPHOSPHONIC+ACID+ESTER+GROUP'>GB</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5o37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o37 OCA], [http://pdbe.org/5o37 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o37 RCSB], [http://www.ebi.ac.uk/pdbsum/5o37 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o37 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5o37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o37 OCA], [http://pdbe.org/5o37 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o37 RCSB], [http://www.ebi.ac.uk/pdbsum/5o37 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o37 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Bisson, C]]		[[Category: Bisson, C]]
	[[Category: Hitchcock, A]]		[[Category: Hitchcock, A]]

OCA at 07:11, 6 December 2017

OCA — Wed, 06 Dec 2017 07:11:37 GMT

←Older revision		Revision as of 07:11, 6 December 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5o37 is ~~ON HOLD~~	+	==Pseudomonas stutzeri PtxB in complex with methylphosphonate (MPn) to 1.37 A resolution==
		+	<StructureSection load='5o37' size='340' side='right' caption='[[5o37]], [[Resolution\|resolution]] 1.37Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5o37]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O37 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5O37 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GB:METHYLPHOSPHONIC+ACID+ESTER+GROUP'>GB</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5o37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o37 OCA], [http://pdbe.org/5o37 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o37 RCSB], [http://www.ebi.ac.uk/pdbsum/5o37 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o37 ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Inorganic phosphate is the major bioavailable form of the essential nutrient phosphorus. However, the concentration of phosphate in most natural habitats is low enough to limit microbial growth. Under phosphate-depleted conditions some bacteria utilise phosphite and hypophosphite as alternative sources of phosphorus, but the molecular basis of reduced phosphorus acquisition from the environment is not fully understood. Here, we present crystal structures and ligand binding affinities of periplasmic binding proteins from bacterial phosphite and hypophosphite ATP-binding cassette transporters. We reveal that phosphite and hypophosphite specificity results from a combination of steric selection and the presence of a P-H...pi interaction between the ligand and a conserved aromatic residue in the ligand-binding pocket. The characterisation of high affinity and specific transporters has implications for the marine phosphorus redox cycle, and might aid the use of phosphite as an alternative phosphorus source in biotechnological, industrial and agricultural applications.

-	~~Authors: Bisson~~, C., ~~Hitchcock~~, A.	+	The molecular basis of phosphite and hypophosphite recognition by ABC-transporters.,Bisson C, Adams NBP, Stevenson B, Brindley AA, Polyviou D, Bibby TS, Baker PJ, Hunter CN, Hitchcock A Nat Commun. 2017 Nov 23;8(1):1746. doi: 10.1038/s41467-017-01226-8. PMID:29170493<ref>PMID:29170493</ref>

-	~~Description: Pseudomonas stutzeri PtxB in complex with methylphosphonate (MPn) to 1~~.~~37 A resolution~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 5o37" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Bisson, C]]		[[Category: Bisson, C]]
	[[Category: Hitchcock, A]]		[[Category: Hitchcock, A]]
		+	[[Category: Abc transporter]]
		+	[[Category: Marine bacteria]]
		+	[[Category: Pbp]]
		+	[[Category: Phosphite]]
		+	[[Category: Sbp]]
		+	[[Category: Transport protein]]

OCA: Protected "5o37" [edit=sysop:move=sysop]

OCA — Wed, 27 Sep 2017 11:59:57 GMT

Protected "5o37" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:59, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 5o37 is ON HOLD Authors: Bisson, C., Hitchcock, A. Description: Pseudomonas stutzeri PtxB in complex with methylphosphonate (MPn) to 1.37 A resolut...

OCA — Wed, 27 Sep 2017 11:59:55 GMT

New page: '''Unreleased structure''' The entry 5o37 is ON HOLD Authors: Bisson, C., Hitchcock, A. Description: Pseudomonas stutzeri PtxB in complex with methylphosphonate (MPn) to 1.37 A resolut...

New page

'''Unreleased structure'''

The entry 5o37 is ON HOLD

Authors: Bisson, C., Hitchcock, A.

Description: Pseudomonas stutzeri PtxB in complex with methylphosphonate (MPn) to 1.37 A resolution
[[Category: Unreleased Structures]]
[[Category: Bisson, C]]
[[Category: Hitchcock, A]]