5ox7 - Revision history

OCA at 01:27, 28 December 2023

OCA — Thu, 28 Dec 2023 01:27:24 GMT

←Older revision		Revision as of 01:27, 28 December 2023
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	==Structure of P110 from Mycoplasma genitalium at 2.4A with potassium ion==		==Structure of P110 from Mycoplasma genitalium at 2.4A with potassium ion==
-	<StructureSection load='5ox7' size='340' side='right' caption='[[5ox7]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='5ox7' size='340' side='right'caption='[[5ox7]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ox7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Mycge Mycge~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OX7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5OX7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ox7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_genitalium_G37 Mycoplasma genitalium G37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OX7 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5mz9\|5mz9]]~~, [[~~5mzb~~\|~~5mzb]], [[5mzd\|5mzd~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~MG192 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=243273 MYCGE])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ox7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ox7 OCA], [https://pdbe.org/5ox7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ox7 RCSB], [https://www.ebi.ac.uk/pdbsum/5ox7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ox7 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ox7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ox7 OCA], [~~http~~://pdbe.org/5ox7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5ox7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5ox7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5ox7 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/MGP3_MYCGE MGP3_MYCGE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 5ox7" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5ox7" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Adhesin 3D structures\|Adhesin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mycge~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Aparicio, D~~]]	+	[[Category: Mycoplasma genitalium G37]]
-	[[Category: ~~Fita, I~~]]	+	[[Category: Aparicio D]]
-	[[Category: ~~Cell adhesion]]~~	+	[[Category: Fita I]]
-	~~[[Category: Mycoplasma genitalium protein d~~]]	+

OCA at 12:32, 7 November 2018

OCA — Wed, 07 Nov 2018 12:32:51 GMT

←Older revision		Revision as of 12:32, 7 November 2018
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ox7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ox7 OCA], [http://pdbe.org/5ox7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ox7 RCSB], [http://www.ebi.ac.uk/pdbsum/5ox7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ox7 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ox7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ox7 OCA], [http://pdbe.org/5ox7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ox7 RCSB], [http://www.ebi.ac.uk/pdbsum/5ox7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ox7 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Adhesion of pathogenic bacteria to target cells is a prerequisite for colonization and further infection. The main adhesins of the emerging sexually transmitted pathogen Mycoplasma genitalium, P140 and P110, interact to form a Nap complex anchored to the cell membrane. Herein, we present the crystal structures of the extracellular region of the virulence factor P110 (916 residues) unliganded and in complex with sialic acid oligosaccharides. P110 interacts only with the neuraminic acid moiety of the oligosaccharides and experiments with human cells demonstrate that these interactions are essential for mycoplasma cytadherence. Additionally, structural information provides a deep insight of the P110 antigenic regions undergoing programmed variation to evade the host immune response. These results enlighten the interplay of M. genitalium with human target cells, offering new strategies to control mycoplasma infections.
		+
		+	Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors.,Aparicio D, Torres-Puig S, Ratera M, Querol E, Pinol J, Pich OQ, Fita I Nat Commun. 2018 Oct 26;9(1):4471. doi: 10.1038/s41467-018-06963-y. PMID:30367053<ref>PMID:30367053</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5ox7" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:26, 17 October 2018

OCA — Wed, 17 Oct 2018 08:26:29 GMT

←Older revision		Revision as of 08:26, 17 October 2018
Line 1:		Line 1:

-	==Mycoplasma genitalium ~~protein D~~==	+	==Structure of P110 from Mycoplasma genitalium at 2.4A with potassium ion==
	<StructureSection load='5ox7' size='340' side='right' caption='[[5ox7]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='5ox7' size='340' side='right' caption='[[5ox7]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ox7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OX7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ox7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycge Mycge]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OX7 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5mz9\|5mz9]], [[5mzb\|5mzb]], [[5mzd\|5mzd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5mz9\|5mz9]], [[5mzb\|5mzb]], [[5mzd\|5mzd]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MG192 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243273 MYCGE])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ox7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ox7 OCA], [http://pdbe.org/5ox7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ox7 RCSB], [http://www.ebi.ac.uk/pdbsum/5ox7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ox7 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ox7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ox7 OCA], [http://pdbe.org/5ox7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ox7 RCSB], [http://www.ebi.ac.uk/pdbsum/5ox7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ox7 ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Mycge]]
	[[Category: Aparicio, D]]		[[Category: Aparicio, D]]
	[[Category: Fita, I]]		[[Category: Fita, I]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]
	[[Category: Mycoplasma genitalium protein d]]		[[Category: Mycoplasma genitalium protein d]]

OCA at 07:46, 10 October 2018

OCA — Wed, 10 Oct 2018 07:46:57 GMT

←Older revision		Revision as of 07:46, 10 October 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5ox7 ~~is ON HOLD until Paper Publication~~	+	==Mycoplasma genitalium protein D==
-		+	<StructureSection load='5ox7' size='340' side='right' caption='[[5ox7]], [[Resolution\|resolution]] 2.40Å' scene=''>
-	~~Authors~~: ~~Aparicio, D~~.~~, Fita, I~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5ox7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OX7 FirstGlance]. <br>
-	~~Description~~: ~~Mycoplasma genitalium protein D~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5mz9\|5mz9]], [[5mzb\|5mzb]], [[5mzd\|5mzd]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ox7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ox7 OCA], [http://pdbe.org/5ox7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ox7 RCSB], [http://www.ebi.ac.uk/pdbsum/5ox7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ox7 ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
	[[Category: Aparicio, D]]		[[Category: Aparicio, D]]
	[[Category: Fita, I]]		[[Category: Fita, I]]
		+	[[Category: Cell adhesion]]
		+	[[Category: Mycoplasma genitalium protein d]]

OCA: Protected "5ox7" [edit=sysop:move=sysop]

OCA — Wed, 27 Sep 2017 12:57:40 GMT

Protected "5ox7" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:57, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 5ox7 is ON HOLD until Paper Publication Authors: Aparicio, D., Fita, I. Description: Mycoplasma genitalium protein D [[Category: Unreleased Structu...

OCA — Wed, 27 Sep 2017 12:57:39 GMT

New page: '''Unreleased structure''' The entry 5ox7 is ON HOLD until Paper Publication Authors: Aparicio, D., Fita, I. Description: Mycoplasma genitalium protein D [[Category: Unreleased Structu...

New page

'''Unreleased structure'''

The entry 5ox7 is ON HOLD until Paper Publication

Authors: Aparicio, D., Fita, I.

Description: Mycoplasma genitalium protein D
[[Category: Unreleased Structures]]
[[Category: Aparicio, D]]
[[Category: Fita, I]]