5q1g - Revision history

OCA at 14:29, 24 January 2024

OCA — Wed, 24 Jan 2024 14:29:12 GMT

←Older revision		Revision as of 14:29, 24 January 2024
Line 1:		Line 1:

-	====	+	==Ligand binding to FARNESOID-X-RECEPTOR==
-	<StructureSection load='5q1g' size='340' side='right'caption='[[5q1g]]' scene=''>	+	<StructureSection load='5q1g' size='340' side='right'caption='[[5q1g]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5q1g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Q1G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Q1G FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5q1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q1g OCA], [https://pdbe.org/5q1g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5q1g RCSB], [https://www.ebi.ac.uk/pdbsum/5q1g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5q1g ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9NM:(2E)-N-cyclohexyl-N-(cyclohexylcarbamoyl)-3-(4-fluorophenyl)prop-2-enamide'>9NM</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5q1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q1g OCA], [https://pdbe.org/5q1g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5q1g RCSB], [https://www.ebi.ac.uk/pdbsum/5q1g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5q1g ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/NR1H4_HUMAN NR1H4_HUMAN] Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.<ref>PMID:10334992</ref> <ref>PMID:10334993</ref> <ref>PMID:12815072</ref> <ref>PMID:15471871</ref> <ref>PMID:12718892</ref> <ref>PMID:18621523</ref> <ref>PMID:19410460</ref> <ref>PMID:19586769</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Drug Design Data Resource (D3R) ran Grand Challenge 2 (GC2) from September 2016 through February 2017. This challenge was based on a dataset of structures and affinities for the nuclear receptor farnesoid X receptor (FXR), contributed by F. Hoffmann-La Roche. The dataset contained 102 IC50 values, spanning six orders of magnitude, and 36 high-resolution co-crystal structures with representatives of four major ligand classes. Strong global participation was evident, with 49 participants submitting 262 prediction submission packages in total. Procedurally, GC2 mimicked Grand Challenge 2015 (GC2015), with a Stage 1 subchallenge testing ligand pose prediction methods and ranking and scoring methods, and a Stage 2 subchallenge testing only ligand ranking and scoring methods after the release of all blinded co-crystal structures. Two smaller curated sets of 18 and 15 ligands were developed to test alchemical free energy methods. This overview summarizes all aspects of GC2, including the dataset details, challenge procedures, and participant results. We also consider implications for progress in the field, while highlighting methodological areas that merit continued development. Similar to GC2015, the outcome of GC2 underscores the pressing need for methods development in pose prediction, particularly for ligand scaffolds not currently represented in the Protein Data Bank ( http://www.pdb.org ), and in affinity ranking and scoring of bound ligands.
		+
		+	D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.,Gaieb Z, Liu S, Gathiaka S, Chiu M, Yang H, Shao C, Feher VA, Walters WP, Kuhn B, Rudolph MG, Burley SK, Gilson MK, Amaro RE J Comput Aided Mol Des. 2017 Dec 4. pii: 10.1007/s10822-017-0088-4. doi:, 10.1007/s10822-017-0088-4. PMID:29204945<ref>PMID:29204945</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5q1g" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Bile acid receptor 3D structures\|Bile acid receptor 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Benz J]]
		+	[[Category: Burger D]]
		+	[[Category: Burley SK]]
		+	[[Category: Joseph C]]
		+	[[Category: Kuhn B]]
		+	[[Category: Rudolph MG]]
		+	[[Category: Ruf A]]
		+	[[Category: Shao C]]
		+	[[Category: Thoma R]]
		+	[[Category: Yang H]]

OCA at 14:02, 17 November 2021

OCA — Wed, 17 Nov 2021 14:02:01 GMT

←Older revision		Revision as of 14:02, 17 November 2021
Line 1:		Line 1:

-	==~~Ligand binding to FARNESOID-X-RECEPTOR~~==	+	====
-	<StructureSection load='5q1g' size='340' side='right' caption='[[5q1g]]~~, [[Resolution\|resolution]] 2.00Å~~' scene=''>	+	<StructureSection load='5q1g' size='340' side='right'caption='[[5q1g]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>~~[[5q1g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human].~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=~~5Q1G~~ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=~~5Q1G~~ FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9NM:(2E)-N-cyclohexyl-N-(cyclohexylcarbamoyl)-3-(4-fluorophenyl)prop-2-enamide'>9NM</scene></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5q1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q1g OCA], [https://pdbe.org/5q1g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5q1g RCSB], [https://www.ebi.ac.uk/pdbsum/5q1g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5q1g ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NR1H4, BAR, FXR, HRR1, RIP14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5q1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q1g OCA], [~~http~~://pdbe.org/5q1g PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5q1g RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5q1g PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5q1g ProSAT]</span></td></tr>	+
	</table>		</table>
-	== Function ==
-	[[http://www.uniprot.org/uniprot/NR1H4_HUMAN NR1H4_HUMAN]] Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.<ref>PMID:10334992</ref> <ref>PMID:10334993</ref> <ref>PMID:12815072</ref> <ref>PMID:15471871</ref> <ref>PMID:12718892</ref> <ref>PMID:18621523</ref> <ref>PMID:19410460</ref> <ref>PMID:19586769</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The Drug Design Data Resource (D3R) ran Grand Challenge 2 (GC2) from September 2016 through February 2017. This challenge was based on a dataset of structures and affinities for the nuclear receptor farnesoid X receptor (FXR), contributed by F. Hoffmann-La Roche. The dataset contained 102 IC50 values, spanning six orders of magnitude, and 36 high-resolution co-crystal structures with representatives of four major ligand classes. Strong global participation was evident, with 49 participants submitting 262 prediction submission packages in total. Procedurally, GC2 mimicked Grand Challenge 2015 (GC2015), with a Stage 1 subchallenge testing ligand pose prediction methods and ranking and scoring methods, and a Stage 2 subchallenge testing only ligand ranking and scoring methods after the release of all blinded co-crystal structures. Two smaller curated sets of 18 and 15 ligands were developed to test alchemical free energy methods. This overview summarizes all aspects of GC2, including the dataset details, challenge procedures, and participant results. We also consider implications for progress in the field, while highlighting methodological areas that merit continued development. Similar to GC2015, the outcome of GC2 underscores the pressing need for methods development in pose prediction, particularly for ligand scaffolds not currently represented in the Protein Data Bank ( http://www.pdb.org ), and in affinity ranking and scoring of bound ligands.
-
-	D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.,Gaieb Z, Liu S, Gathiaka S, Chiu M, Yang H, Shao C, Feher VA, Walters WP, Kuhn B, Rudolph MG, Burley SK, Gilson MK, Amaro RE J Comput Aided Mol Des. 2017 Dec 4. pii: 10.1007/s10822-017-0088-4. doi:, 10.1007/s10822-017-0088-4. PMID:29204945<ref>PMID:29204945</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5q1g" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Benz, J]]~~	+	[[Category: Z-disk]]
-	~~[[Category: Burger, D]]~~	+
-	~~[[Category: Burley, S K]]~~	+
-	~~[[Category: Joseph, C]]~~	+
-	~~[[Category: Kuhn, B]]~~	+
-	~~[[Category: Rudolph, M G]]~~	+
-	~~[[Category: Ruf, A]]~~	+
-	~~[[Category: Shao, C]]~~	+
-	~~[[Category: Thoma, R]]~~	+
-	~~[[Category: Yang, H]]~~	+
-	~~[[Category: D3r]]~~	+
-	~~[[Category: Docking]]~~	+
-	~~[[Category: Fxr]]~~	+
-	~~[[Category: Transcription~~]]	+

OCA at 06:41, 20 December 2017

OCA — Wed, 20 Dec 2017 06:41:15 GMT

←Older revision		Revision as of 06:41, 20 December 2017
Line 3:		Line 3:
	<StructureSection load='5q1g' size='340' side='right' caption='[[5q1g]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='5q1g' size='340' side='right' caption='[[5q1g]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5q1g]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Q1G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Q1G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5q1g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Q1G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Q1G FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9NM:(2E)-N-cyclohexyl-N-(cyclohexylcarbamoyl)-3-(4-fluorophenyl)prop-2-enamide'>9NM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9NM:(2E)-N-cyclohexyl-N-(cyclohexylcarbamoyl)-3-(4-fluorophenyl)prop-2-enamide'>9NM</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NR1H4, BAR, FXR, HRR1, RIP14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5q1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q1g OCA], [http://pdbe.org/5q1g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5q1g RCSB], [http://www.ebi.ac.uk/pdbsum/5q1g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5q1g ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5q1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q1g OCA], [http://pdbe.org/5q1g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5q1g RCSB], [http://www.ebi.ac.uk/pdbsum/5q1g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5q1g ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/NR1H4_HUMAN NR1H4_HUMAN]] Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.<ref>PMID:10334992</ref> <ref>PMID:10334993</ref> <ref>PMID:12815072</ref> <ref>PMID:15471871</ref> <ref>PMID:12718892</ref> <ref>PMID:18621523</ref> <ref>PMID:19410460</ref> <ref>PMID:19586769</ref>		[[http://www.uniprot.org/uniprot/NR1H4_HUMAN NR1H4_HUMAN]] Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.<ref>PMID:10334992</ref> <ref>PMID:10334993</ref> <ref>PMID:12815072</ref> <ref>PMID:15471871</ref> <ref>PMID:12718892</ref> <ref>PMID:18621523</ref> <ref>PMID:19410460</ref> <ref>PMID:19586769</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Drug Design Data Resource (D3R) ran Grand Challenge 2 (GC2) from September 2016 through February 2017. This challenge was based on a dataset of structures and affinities for the nuclear receptor farnesoid X receptor (FXR), contributed by F. Hoffmann-La Roche. The dataset contained 102 IC50 values, spanning six orders of magnitude, and 36 high-resolution co-crystal structures with representatives of four major ligand classes. Strong global participation was evident, with 49 participants submitting 262 prediction submission packages in total. Procedurally, GC2 mimicked Grand Challenge 2015 (GC2015), with a Stage 1 subchallenge testing ligand pose prediction methods and ranking and scoring methods, and a Stage 2 subchallenge testing only ligand ranking and scoring methods after the release of all blinded co-crystal structures. Two smaller curated sets of 18 and 15 ligands were developed to test alchemical free energy methods. This overview summarizes all aspects of GC2, including the dataset details, challenge procedures, and participant results. We also consider implications for progress in the field, while highlighting methodological areas that merit continued development. Similar to GC2015, the outcome of GC2 underscores the pressing need for methods development in pose prediction, particularly for ligand scaffolds not currently represented in the Protein Data Bank ( http://www.pdb.org ), and in affinity ranking and scoring of bound ligands.
		+
		+	D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.,Gaieb Z, Liu S, Gathiaka S, Chiu M, Yang H, Shao C, Feher VA, Walters WP, Kuhn B, Rudolph MG, Burley SK, Gilson MK, Amaro RE J Comput Aided Mol Des. 2017 Dec 4. pii: 10.1007/s10822-017-0088-4. doi:, 10.1007/s10822-017-0088-4. PMID:29204945<ref>PMID:29204945</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5q1g" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Benz, J]]		[[Category: Benz, J]]
	[[Category: Burger, D]]		[[Category: Burger, D]]

OCA at 16:56, 20 October 2017

OCA — Fri, 20 Oct 2017 16:56:13 GMT

←Older revision		Revision as of 16:56, 20 October 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5q1g ~~is ON HOLD~~	+	==Ligand binding to FARNESOID-X-RECEPTOR==
-		+	<StructureSection load='5q1g' size='340' side='right' caption='[[5q1g]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~Authors~~: ~~Benz, J~~.~~, Burger, D~~.~~, Joseph, C~~.~~, Rudolph, M~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5q1g]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Q1G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Q1G FirstGlance]. <br>
-	~~Description~~: Ligand ~~binding to FARNESOID~~-X-~~RECEPTOR~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9NM:(2E)-N-cyclohexyl-N-(cyclohexylcarbamoyl)-3-(4-fluorophenyl)prop-2-enamide'>9NM</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5q1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q1g OCA], [http://pdbe.org/5q1g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5q1g RCSB], [http://www.ebi.ac.uk/pdbsum/5q1g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5q1g ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Joseph~~, C]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NR1H4_HUMAN NR1H4_HUMAN]] Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.<ref>PMID:10334992</ref> <ref>PMID:10334993</ref> <ref>PMID:12815072</ref> <ref>PMID:15471871</ref> <ref>PMID:12718892</ref> <ref>PMID:18621523</ref> <ref>PMID:19410460</ref> <ref>PMID:19586769</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Benz, J]]		[[Category: Benz, J]]
-	[[Category: Rudolph, M]]
	[[Category: Burger, D]]		[[Category: Burger, D]]
		+	[[Category: Burley, S K]]
		+	[[Category: Joseph, C]]
		+	[[Category: Kuhn, B]]
		+	[[Category: Rudolph, M G]]
		+	[[Category: Ruf, A]]
		+	[[Category: Shao, C]]
		+	[[Category: Thoma, R]]
		+	[[Category: Yang, H]]
		+	[[Category: D3r]]
		+	[[Category: Docking]]
		+	[[Category: Fxr]]
		+	[[Category: Transcription]]

OCA: Protected "5q1g" [edit=sysop:move=sysop]

OCA — Wed, 17 May 2017 12:33:49 GMT

Protected "5q1g" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:33, 17 May 2017

OCA: New page: '''Unreleased structure''' The entry 5q1g is ON HOLD Authors: Benz, J., Burger, D., Joseph, C., Rudolph, M. Description: Ligand binding to FARNESOID-X-RECEPTOR [[Category: Unreleased S...

OCA — Wed, 17 May 2017 12:33:48 GMT

New page: '''Unreleased structure''' The entry 5q1g is ON HOLD Authors: Benz, J., Burger, D., Joseph, C., Rudolph, M. Description: Ligand binding to FARNESOID-X-RECEPTOR [[Category: Unreleased S...

New page

'''Unreleased structure'''

The entry 5q1g is ON HOLD

Authors: Benz, J., Burger, D., Joseph, C., Rudolph, M.

Description: Ligand binding to FARNESOID-X-RECEPTOR
[[Category: Unreleased Structures]]
[[Category: Joseph, C]]
[[Category: Benz, J]]
[[Category: Rudolph, M]]
[[Category: Burger, D]]