5qhq - Revision history

OCA at 08:54, 7 February 2024

OCA — Wed, 07 Feb 2024 08:54:56 GMT

←Older revision		Revision as of 08:54, 7 February 2024
Line 3:		Line 3:
	<StructureSection load='5qhq' size='340' side='right'caption='[[5qhq]], [[Resolution\|resolution]] 1.96Å' scene=''>		<StructureSection load='5qhq' size='340' side='right'caption='[[5qhq]], [[Resolution\|resolution]] 1.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5qhq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5QHQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5qhq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QHQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GQP:1-[(4-fluorophenyl)methyl]benzimidazole'>GQP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.96Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5qhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhq OCA], [~~http~~://pdbe.org/5qhq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5qhq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5qhq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhq ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GQP:1-[(4-fluorophenyl)methyl]benzimidazole'>GQP</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhq OCA], [https://pdbe.org/5qhq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qhq RCSB], [https://www.ebi.ac.uk/pdbsum/5qhq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/FA83B_HUMAN FA83B_HUMAN]] Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.<ref>PMID:22886302</ref> <ref>PMID:23676467</ref> <ref>PMID:23912460</ref>	+	[https://www.uniprot.org/uniprot/FA83B_HUMAN FA83B_HUMAN] Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.<ref>PMID:22886302</ref> <ref>PMID:23676467</ref> <ref>PMID:23912460</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arrowsmith~~, C H~~]]	+	[[Category: Arrowsmith CH]]
-	[[Category: Bountra, C]]	+	[[Category: Bountra C]]
-	[[Category: Bufton~~, J C~~]]	+	[[Category: Bufton JC]]
-	[[Category: Bullock~~, A N~~]]	+	[[Category: Bullock AN]]
-	[[Category: Collins, P]]	+	[[Category: Collins P]]
-	~~[[Category: Delft, F von~~]]	+	[[Category: Douangamath A]]
-	[[Category: Douangamath, A]]	+	[[Category: Edwards A]]
-	[[Category: Edwards, A]]	+	[[Category: Fox AE]]
-	[[Category: Fox~~, A E~~]]	+	[[Category: Krojer T]]
-	[[Category: Krojer, T]]	+	[[Category: Pinkas DM]]
-	[[Category: Pinkas~~, D M~~]]	+	[[Category: Talon R]]
-	[[Category: Talon, R]]	+	[[Category: Zhang R]]
-	[[Category: Zhang, R]]	+	[[Category: Von Delft F]]
-	[[Category: ~~Duf1669 domain]]~~	+
-	~~[[Category: Pandda]]~~	+
-	~~[[Category: Protein binding]]~~	+
-	~~[[Category: Sgc - diamond i04-1 fragment screening]]~~	+
-	~~[[Category: Xchemexplorer~~]]	+

OCA at 12:05, 23 September 2020

OCA — Wed, 23 Sep 2020 12:05:40 GMT

←Older revision		Revision as of 12:05, 23 September 2020
Line 1:		Line 1:

	==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000574a==		==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000574a==
-	<StructureSection load='5qhq' size='340' side='right' caption='[[5qhq]], [[Resolution\|resolution]] 1.96Å' scene=''>	+	<StructureSection load='5qhq' size='340' side='right'caption='[[5qhq]], [[Resolution\|resolution]] 1.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5qhq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHQ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5QHQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5qhq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5QHQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GQP:1-[(4-fluorophenyl)methyl]benzimidazole'>GQP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GQP:1-[(4-fluorophenyl)methyl]benzimidazole'>GQP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5qhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhq OCA], [http://pdbe.org/5qhq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qhq RCSB], [http://www.ebi.ac.uk/pdbsum/5qhq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5qhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhq OCA], [http://pdbe.org/5qhq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qhq RCSB], [http://www.ebi.ac.uk/pdbsum/5qhq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 13:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bountra, C]]		[[Category: Bountra, C]]

OCA at 08:05, 19 December 2018

OCA — Wed, 19 Dec 2018 08:05:36 GMT

←Older revision		Revision as of 08:05, 19 December 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5qhq ~~is ON HOLD~~	+	==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000574a==
-		+	<StructureSection load='5qhq' size='340' side='right' caption='[[5qhq]], [[Resolution\|resolution]] 1.96Å' scene=''>
-	~~Authors~~: ~~Pinkas, D~~.M.~~, Bufton, J~~.C.~~, Fox, A~~.E.~~, Talon, R~~.~~, Krojer, T~~.~~, Douangamath, A~~., ~~Collins~~, P.~~, Zhang, R~~., ~~von Delft, F~~., ~~Bountra, C~~., ~~Arrowsmith, C~~.H., ~~Edwards, A~~., ~~Bullock, A~~.N.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5qhq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QHQ FirstGlance]. <br>
-	~~Description~~: ~~PanDDA analysis group deposition of models with modelled events (e~~.g. ~~bound ligands)~~ -~~-Crystal Structure of human FAM83B~~ in ~~complex with FMOPL000574a~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GQP:1-[(4-fluorophenyl)methyl]benzimidazole'>GQP</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhq OCA], [http://pdbe.org/5qhq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qhq RCSB], [http://www.ebi.ac.uk/pdbsum/5qhq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhq ProSAT]</span></td></tr>
-	[[Category: ~~Zhang~~, R]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FA83B_HUMAN FA83B_HUMAN]] Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.<ref>PMID:22886302</ref> <ref>PMID:23676467</ref> <ref>PMID:23912460</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Arrowsmith, C H]]
		+	[[Category: Bountra, C]]
		+	[[Category: Bufton, J C]]
		+	[[Category: Bullock, A N]]
	[[Category: Collins, P]]		[[Category: Collins, P]]
-	[[Category: ~~Pinkas~~, ~~D.M~~]]	+	[[Category: Delft, F von]]
-	[[Category: ~~Fox~~, A~~.E]]~~	+	[[Category: Douangamath, A]]
-	~~[[Category: Arrowsmith, C.H]]~~	+
-	~~[[Category: Talon, R~~]]	+
	[[Category: Edwards, A]]		[[Category: Edwards, A]]
-	[[Category: ~~Douangamath~~, A]]	+	[[Category: Fox, A E]]
	[[Category: Krojer, T]]		[[Category: Krojer, T]]
-	[[Category: ~~Von Delft~~, F]]	+	[[Category: Pinkas, D M]]
-	[[Category: ~~Bountra~~, C]]	+	[[Category: Talon, R]]
-	[[Category: ~~Bullock~~, ~~A.N~~]]	+	[[Category: Zhang, R]]
-	[[Category: ~~Bufton, J.C~~]]	+	[[Category: Duf1669 domain]]
		+	[[Category: Pandda]]
		+	[[Category: Protein binding]]
		+	[[Category: Sgc - diamond i04-1 fragment screening]]
		+	[[Category: Xchemexplorer]]

OCA: Protected "5qhq" [edit=sysop:move=sysop]

OCA — Wed, 30 May 2018 03:46:23 GMT

Protected "5qhq" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:46, 30 May 2018

OCA: New page: '''Unreleased structure''' The entry 5qhq is ON HOLD Authors: Pinkas, D.M., Bufton, J.C., Fox, A.E., Talon, R., Krojer, T., Douangamath, A., Collins, P., Zhang, R., von Delft, F., Bount...

OCA — Wed, 30 May 2018 03:46:22 GMT

New page: '''Unreleased structure''' The entry 5qhq is ON HOLD Authors: Pinkas, D.M., Bufton, J.C., Fox, A.E., Talon, R., Krojer, T., Douangamath, A., Collins, P., Zhang, R., von Delft, F., Bount...

New page

'''Unreleased structure'''

The entry 5qhq is ON HOLD

Authors: Pinkas, D.M., Bufton, J.C., Fox, A.E., Talon, R., Krojer, T., Douangamath, A., Collins, P., Zhang, R., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Bullock, A.N.

Description: PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) --Crystal Structure of human FAM83B in complex with FMOPL000574a
[[Category: Unreleased Structures]]
[[Category: Zhang, R]]
[[Category: Collins, P]]
[[Category: Pinkas, D.M]]
[[Category: Fox, A.E]]
[[Category: Arrowsmith, C.H]]
[[Category: Talon, R]]
[[Category: Edwards, A]]
[[Category: Douangamath, A]]
[[Category: Krojer, T]]
[[Category: Von Delft, F]]
[[Category: Bountra, C]]
[[Category: Bullock, A.N]]
[[Category: Bufton, J.C]]