5qig - Revision history

OCA at 08:55, 7 February 2024

OCA — Wed, 07 Feb 2024 08:55:43 GMT

←Older revision		Revision as of 08:55, 7 February 2024
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	==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with Z1407672867==		==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with Z1407672867==
-	<StructureSection load='5qig' size='340' side='right' caption='[[5qig]], [[Resolution\|resolution]] 1.42Å' scene=''>	+	<StructureSection load='5qig' size='340' side='right'caption='[[5qig]], [[Resolution\|resolution]] 1.42Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5qig]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5QIG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5qig]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QIG FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene~~>, ~~<scene name='pdbligand=GWP:2-cyclopropyl-~~1~~~{H}-imidazole-4-carboxamide'>GWP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.42Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>HAO1, GOX1, HAOX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~9606 HUMAN])</td~~><~~/tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GWP:2-cyclopropyl-1~{H}-imidazole-4-carboxamide'>GWP</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[http~~:~~//en.wikipedia.org/wiki/(S)-~~2-~~hydroxy~~-~~acid_oxidase (S)~~-2-~~hydroxy~~-~~acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15]~~ </~~span~~></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qig OCA], [https://pdbe.org/5qig PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qig RCSB], [https://www.ebi.ac.uk/pdbsum/5qig PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qig ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5qig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qig OCA], [~~http~~://pdbe.org/5qig PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5qig RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5qig PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5qig ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN]] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.	+	[https://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.
		+
		+	==See Also==
		+	*[[Glycolate oxidase 3D structures\|Glycolate oxidase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: Arrowsmith~~, C H~~]]	+	[[Category: Large Structures]]
-	[[Category: Bezerra~~, G A~~]]	+	[[Category: Arrowsmith CH]]
-	[[Category: Bountra, C]]	+	[[Category: Bezerra GA]]
-	[[Category: Bradley~~, A R~~]]	+	[[Category: Bountra C]]
-	[[Category: Brandao-Neto, J]]	+	[[Category: Bradley AR]]
-	[[Category: Brennan~~, P E]]~~	+	[[Category: Brandao-Neto J]]
-	~~[[Category: Delft, F von~~]]	+	[[Category: Brennan PE]]
-	[[Category: Douangamath, A]]	+	[[Category: Douangamath A]]
-	[[Category: Edwards, A]]	+	[[Category: Edwards A]]
-	[[Category: Krojer, T]]	+	[[Category: Krojer T]]
-	[[Category: MacKinnon, S]]	+	[[Category: MacKinnon S]]
-	[[Category: Oppermann, U]]	+	[[Category: Oppermann U]]
-	[[Category: Talon, R]]	+	[[Category: Talon R]]
-	[[Category: Yue~~, W W~~]]	+	[[Category: Yue WW]]
-	[[Category: ~~Hao1]]~~	+	[[Category: Von Delft F]]
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Pandda]]~~	+
-	~~[[Category: Sgc - diamond i04-1 fragment screening]]~~	+
-	~~[[Category: Xchemexplorer~~]]	+

OCA at 16:34, 15 August 2018

OCA — Wed, 15 Aug 2018 16:34:34 GMT

←Older revision		Revision as of 16:34, 15 August 2018
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	<StructureSection load='5qig' size='340' side='right' caption='[[5qig]], [[Resolution\|resolution]] 1.42Å' scene=''>		<StructureSection load='5qig' size='340' side='right' caption='[[5qig]], [[Resolution\|resolution]] 1.42Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5qig]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QIG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5qig]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QIG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GWP:2-cyclopropyl-1~{H}-imidazole-4-carboxamide'>GWP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GWP:2-cyclopropyl-1~{H}-imidazole-4-carboxamide'>GWP</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HAO1, GOX1, HAOX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qig OCA], [http://pdbe.org/5qig PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qig RCSB], [http://www.ebi.ac.uk/pdbsum/5qig PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qig ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qig OCA], [http://pdbe.org/5qig PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qig RCSB], [http://www.ebi.ac.uk/pdbsum/5qig PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qig ProSAT]</span></td></tr>
Line 12:		Line 13:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bezerra, G A]]		[[Category: Bezerra, G A]]

OCA at 07:21, 18 July 2018

OCA — Wed, 18 Jul 2018 07:21:16 GMT

←Older revision		Revision as of 07:21, 18 July 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5qig ~~is ON HOLD~~	+	==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with Z1407672867==
-		+	<StructureSection load='5qig' size='340' side='right' caption='[[5qig]], [[Resolution\|resolution]] 1.42Å' scene=''>
-	~~Authors~~: ~~MacKinnon, S~~.~~, Bezerra, G~~.A.~~, Krojer, T~~.~~, Bradley, A~~.R.~~, Talon, R~~.~~, Brandao~~-~~Neto, J~~.~~, Douangamath, A~~., ~~von Delft, F~~., ~~Arrowsmith, C~~.H., ~~Edwards, A~~., ~~Bountra, C~~., ~~Oppermann, U~~., ~~Brennan, P~~.E., ~~Yue, W~~.W.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5qig]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QIG FirstGlance]. <br>
-	~~Description~~: ~~PanDDA analysis group deposition of models with modelled events (e~~.g. ~~bound ligands)~~ --~~Crystal Structure of HAO1 in complex~~ with ~~Z1407672867~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GWP:2-cyclopropyl-1~{H}-imidazole-4-carboxamide'>GWP</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] </span></td></tr>
-	[[Category: ~~Mackinnon~~, S]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qig OCA], [http://pdbe.org/5qig PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qig RCSB], [http://www.ebi.ac.uk/pdbsum/5qig PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qig ProSAT]</span></td></tr>
-	[[Category: ~~Bradley~~, ~~A.R~~]]	+	</table>
-	[[Category: ~~Arrowsmith~~, ~~C.H~~]]	+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN]] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Arrowsmith, C H]]
		+	[[Category: Bezerra, G A]]
		+	[[Category: Bountra, C]]
		+	[[Category: Bradley, A R]]
	[[Category: Brandao-Neto, J]]		[[Category: Brandao-Neto, J]]
-	~~[[Category: Talon, R]]~~	+	[[Category: Brennan, P E]]
-	[[Category: Brennan, P.E]]	+	[[Category: Delft, F von]]
-	[[Category: ~~Oppermann~~, U]]	+	[[Category: Douangamath, A]]
-	[[Category: ~~Bezerra~~, G.A]]	+
	[[Category: Edwards, A]]		[[Category: Edwards, A]]
-	[[Category: Douangamath, A]]
	[[Category: Krojer, T]]		[[Category: Krojer, T]]
-	[[Category: Yue, W.W]]	+	[[Category: MacKinnon, S]]
-	[[Category: ~~Von Delft, F~~]]	+	[[Category: Oppermann, U]]
-	[[Category: ~~Bountra, C~~]]	+	[[Category: Talon, R]]
		+	[[Category: Yue, W W]]
		+	[[Category: Hao1]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Pandda]]
		+	[[Category: Sgc - diamond i04-1 fragment screening]]
		+	[[Category: Xchemexplorer]]

OCA: Protected "5qig" [edit=sysop:move=sysop]

OCA — Wed, 30 May 2018 03:47:58 GMT

Protected "5qig" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:47, 30 May 2018

OCA: New page: '''Unreleased structure''' The entry 5qig is ON HOLD Authors: MacKinnon, S., Bezerra, G.A., Krojer, T., Bradley, A.R., Talon, R., Brandao-Neto, J., Douangamath, A., von Delft, F., Arrow...

OCA — Wed, 30 May 2018 03:47:57 GMT

New page: '''Unreleased structure''' The entry 5qig is ON HOLD Authors: MacKinnon, S., Bezerra, G.A., Krojer, T., Bradley, A.R., Talon, R., Brandao-Neto, J., Douangamath, A., von Delft, F., Arrow...

New page

'''Unreleased structure'''

The entry 5qig is ON HOLD

Authors: MacKinnon, S., Bezerra, G.A., Krojer, T., Bradley, A.R., Talon, R., Brandao-Neto, J., Douangamath, A., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Oppermann, U., Brennan, P.E., Yue, W.W.

Description: PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) --Crystal Structure of HAO1 in complex with Z1407672867
[[Category: Unreleased Structures]]
[[Category: Mackinnon, S]]
[[Category: Bradley, A.R]]
[[Category: Arrowsmith, C.H]]
[[Category: Brandao-Neto, J]]
[[Category: Talon, R]]
[[Category: Brennan, P.E]]
[[Category: Oppermann, U]]
[[Category: Bezerra, G.A]]
[[Category: Edwards, A]]
[[Category: Douangamath, A]]
[[Category: Krojer, T]]
[[Category: Yue, W.W]]
[[Category: Von Delft, F]]
[[Category: Bountra, C]]