5qsq - Revision history

OCA at 11:26, 21 February 2024

OCA — Wed, 21 Feb 2024 11:26:49 GMT

←Older revision		Revision as of 11:26, 21 February 2024
Line 3:		Line 3:
	<StructureSection load='5qsq' size='340' side='right'caption='[[5qsq]], [[Resolution\|resolution]] 2.48Å' scene=''>		<StructureSection load='5qsq' size='340' side='right'caption='[[5qsq]], [[Resolution\|resolution]] 2.48Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5qsq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QSQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5QSQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5qsq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QSQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HR5:~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide'>HR5</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.48Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qsq OCA], [~~http~~://pdbe.org/5qsq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5qsq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5qsq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5qsq ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HR5:~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide'>HR5</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qsq OCA], [https://pdbe.org/5qsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qsq RCSB], [https://www.ebi.ac.uk/pdbsum/5qsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qsq ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[~~[http~~://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN]] STAG1-related intellectual disability-facial dysmorphism-gastroesophageal reflux syndrome. The disease is caused by mutations affecting the gene represented in this entry.	+	[https://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN] STAG1-related intellectual disability-facial dysmorphism-gastroesophageal reflux syndrome. The disease is caused by mutations affecting the gene represented in this entry.
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN]] Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.	+	[https://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN] Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arrowsmith~~, C H~~]]	+	[[Category: Arrowsmith CH]]
-	[[Category: Bountra, C]]	+	[[Category: Bountra C]]
-	~~[[Category: Delft, F von~~]]	+	[[Category: Edwards A]]
-	[[Category: Edwards, A]]	+	[[Category: Gavard AE]]
-	[[Category: Gavard~~, A E~~]]	+	[[Category: Gileadi O]]
-	[[Category: Gileadi, O]]	+	[[Category: Katis VL]]
-	[[Category: Katis~~, V L~~]]	+	[[Category: Newman JA]]
-	[[Category: Newman~~, J A~~]]	+	[[Category: Von Delft F]]
-	[[Category: ~~Pandda]]~~	+
-	~~[[Category: Sgc - diamond i04-1 fragment screening]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Xchemexplorer~~]]	+

OCA at 05:47, 21 August 2019

OCA — Wed, 21 Aug 2019 05:47:03 GMT

←Older revision		Revision as of 05:47, 21 August 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5qsq ~~is ON HOLD~~	+	==PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z396380540==
-		+	<StructureSection load='5qsq' size='340' side='right'caption='[[5qsq]], [[Resolution\|resolution]] 2.48Å' scene=''>
-	~~Authors~~: ~~Newman, J~~.A.~~, Katis, V~~.L.~~, Gavard, A~~.E., ~~von Delft, F~~., ~~Arrowsmith, C~~.H., ~~Edwards, A~~., ~~Bountra, C~~., ~~Gileadi~~, O.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5qsq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QSQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QSQ FirstGlance]. <br>
-	~~Description~~: ~~PanDDA analysis group deposition~~ --~~Crystal Structure of human STAG1~~ in complex ~~with Z396380540~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HR5:~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide'>HR5</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qsq OCA], [http://pdbe.org/5qsq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qsq RCSB], [http://www.ebi.ac.uk/pdbsum/5qsq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qsq ProSAT]</span></td></tr>
-	[[Category: ~~Katis~~, ~~V.L~~]]	+	</table>
-	[[Category: ~~Arrowsmith~~, C.H]]	+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN]] STAG1-related intellectual disability-facial dysmorphism-gastroesophageal reflux syndrome. The disease is caused by mutations affecting the gene represented in this entry.
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN]] Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Arrowsmith, C H]]
		+	[[Category: Bountra, C]]
		+	[[Category: Delft, F von]]
		+	[[Category: Edwards, A]]
		+	[[Category: Gavard, A E]]
	[[Category: Gileadi, O]]		[[Category: Gileadi, O]]
-	[[Category: Newman, J.A]]	+	[[Category: Katis, V L]]
-	[[Category: ~~Edwards, A~~]]	+	[[Category: Newman, J A]]
-	[[Category: ~~Gavard, A.E~~]]	+	[[Category: Pandda]]
-	[[Category: ~~Von Delft, F~~]]	+	[[Category: Sgc - diamond i04-1 fragment screening]]
-	[[Category: ~~Bountra, C~~]]	+	[[Category: Transcription]]
		+	[[Category: Xchemexplorer]]

OCA: Protected "5qsq" [edit=sysop:move=sysop]

OCA — Wed, 05 Jun 2019 20:51:54 GMT

Protected "5qsq" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:51, 5 June 2019

OCA: New page: '''Unreleased structure''' The entry 5qsq is ON HOLD Authors: Newman, J.A., Katis, V.L., Gavard, A.E., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O. Descriptio...

OCA — Wed, 05 Jun 2019 20:51:53 GMT

New page: '''Unreleased structure''' The entry 5qsq is ON HOLD Authors: Newman, J.A., Katis, V.L., Gavard, A.E., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O. Descriptio...

New page

'''Unreleased structure'''

The entry 5qsq is ON HOLD

Authors: Newman, J.A., Katis, V.L., Gavard, A.E., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.

Description: PanDDA analysis group deposition --Crystal Structure of human STAG1 in complex with Z396380540
[[Category: Unreleased Structures]]
[[Category: Katis, V.L]]
[[Category: Arrowsmith, C.H]]
[[Category: Gileadi, O]]
[[Category: Newman, J.A]]
[[Category: Edwards, A]]
[[Category: Gavard, A.E]]
[[Category: Von Delft, F]]
[[Category: Bountra, C]]