5r4s - Revision history

OCA at 11:35, 21 February 2024

OCA — Wed, 21 Feb 2024 11:35:37 GMT

←Older revision		Revision as of 11:35, 21 February 2024
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	==PanDDA analysis group deposition -- Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with EN08775-45==		==PanDDA analysis group deposition -- Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with EN08775-45==
-	<StructureSection load='5r4s' size='340' side='right'caption='[[5r4s]]' scene=''>	+	<StructureSection load='5r4s' size='340' side='right'caption='[[5r4s]], [[Resolution\|resolution]] 1.61Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R4S OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5R4S FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5r4s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R4S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5R4S FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5r4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r4s OCA], [~~http~~://pdbe.org/5r4s PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5r4s RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5r4s PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5r4s ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.61Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=RWD:(4S,5R)-4-hydroxy-5-methyl-5-[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]pyrrolidin-2-one'>RWD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5r4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r4s OCA], [https://pdbe.org/5r4s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5r4s RCSB], [https://www.ebi.ac.uk/pdbsum/5r4s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5r4s ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CPSF5_HUMAN CPSF5_HUMAN] Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export.<ref>PMID:9659921</ref> <ref>PMID:8626397</ref> <ref>PMID:14690600</ref> <ref>PMID:20695905</ref> <ref>PMID:20479262</ref> <ref>PMID:21295486</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Aimon A]]		[[Category: Aimon A]]

OCA at 13:57, 8 July 2020

OCA — Wed, 08 Jul 2020 13:57:41 GMT

←Older revision		Revision as of 13:57, 8 July 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 5r4s ~~is ON HOLD~~	+	==PanDDA analysis group deposition -- Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with EN08775-45==
-		+	<StructureSection load='5r4s' size='340' side='right'caption='[[5r4s]]' scene=''>
-	~~Authors~~: ~~Kidd, S~~.L.~~, Mateu, N~~.~~, Talon, R~~.~~, Krojer, T~~.~~, Aimon, A~~.~~, Bradley, A~~.R., ~~Fairhead, M~~.~~, Diaz~~-~~Saez~~, L., ~~Sore, H~~.F.~~, Madin, A~~., ~~Huber, K~~.V.M., ~~von Delft, F~~.~~, Spring, D.R~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R4S OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5R4S FirstGlance]. <br>
-	~~Description: PanDDA analysis group deposition --Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with EN08775-45~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5r4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r4s OCA], [http://pdbe.org/5r4s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5r4s RCSB], [http://www.ebi.ac.uk/pdbsum/5r4s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5r4s ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Spring, D.R~~]]	+	__TOC__
-	[[Category: ~~Aimon, A~~]]	+	</StructureSection>
-	[[Category: ~~Mateu, N~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Kidd, S.L~~]]	+	[[Category: Aimon A]]
-	[[Category: ~~Bradley, A.R~~]]	+	[[Category: Bradley AR]]
-	[[Category: ~~Talon, R~~]]	+	[[Category: Diaz-Saez L]]
-	[[Category: ~~Huber, K.V.M~~]]	+	[[Category: Fairhead M]]
-	[[Category: ~~Sore, H.F~~]]	+	[[Category: Huber KVM]]
-	[[Category: ~~Madin, A~~]]	+	[[Category: Kidd SL]]
-	[[Category: ~~Diaz-Saez, L~~]]	+	[[Category: Krojer T]]
-	[[Category: ~~Krojer, T~~]]	+	[[Category: Madin A]]
-	[[Category: ~~Fairhead, M~~]]	+	[[Category: Mateu N]]
-	[[Category: Von Delft, F]]	+	[[Category: Sore HF]]
		+	[[Category: Spring DR]]
		+	[[Category: Talon R]]
		+	[[Category: Von Delft F]]

OCA at 08:07, 18 March 2020

OCA — Wed, 18 Mar 2020 08:07:01 GMT

←Older revision		Revision as of 08:07, 18 March 2020
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	The entry 5r4s is ON HOLD		The entry 5r4s is ON HOLD

-	Authors: Kidd, S.L., Mateu, N., Talon, R., Krojer, T., Aimon, A., Bradley, A.R., Fairhead, M., ~~Dez~~, L., Sore, H.F., Madin, A., Huber, K.V.M., von Delft, F., Spring, D.R.	+	Authors: Kidd, S.L., Mateu, N., Talon, R., Krojer, T., Aimon, A., Bradley, A.R., Fairhead, M., Diaz-Saez, L., Sore, H.F., Madin, A., Huber, K.V.M., von Delft, F., Spring, D.R.

	Description: PanDDA analysis group deposition --Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with EN08775-45		Description: PanDDA analysis group deposition --Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with EN08775-45
Line 10:		Line 10:
	[[Category: Aimon, A]]		[[Category: Aimon, A]]
	[[Category: Mateu, N]]		[[Category: Mateu, N]]
-	[[Category: Dez, L]]
	[[Category: Kidd, S.L]]		[[Category: Kidd, S.L]]
	[[Category: Bradley, A.R]]		[[Category: Bradley, A.R]]
Line 17:		Line 16:
	[[Category: Sore, H.F]]		[[Category: Sore, H.F]]
	[[Category: Madin, A]]		[[Category: Madin, A]]
		+	[[Category: Diaz-Saez, L]]
	[[Category: Krojer, T]]		[[Category: Krojer, T]]
	[[Category: Fairhead, M]]		[[Category: Fairhead, M]]
	[[Category: Von Delft, F]]		[[Category: Von Delft, F]]

OCA at 05:45, 11 March 2020

OCA — Wed, 11 Mar 2020 05:45:36 GMT

←Older revision		Revision as of 05:45, 11 March 2020
Line 3:		Line 3:
	The entry 5r4s is ON HOLD		The entry 5r4s is ON HOLD

-	Authors: Kidd, S.L., Mateu, N., Talon, R., Krojer, T., Aimon, A., Bradley, A.R., Fairhead, M., ~~DÃÆÃÆÃâÃÂaz-SÃÆÃÆÃâÃÂ¡ez~~, L., Sore, H.F., Madin, A., Huber, K.V.M., von Delft, F., Spring, D.R.	+	Authors: Kidd, S.L., Mateu, N., Talon, R., Krojer, T., Aimon, A., Bradley, A.R., Fairhead, M., Dez, L., Sore, H.F., Madin, A., Huber, K.V.M., von Delft, F., Spring, D.R.

	Description: PanDDA analysis group deposition --Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with EN08775-45		Description: PanDDA analysis group deposition --Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with EN08775-45
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Spring, D.R]]		[[Category: Spring, D.R]]
-	[[Category: DãÆÃÆÃÂÃÂAz-SãÆÃÆÃÂÃÂ¡Ez, L]]
	[[Category: Aimon, A]]		[[Category: Aimon, A]]
	[[Category: Mateu, N]]		[[Category: Mateu, N]]
		+	[[Category: Dez, L]]
	[[Category: Kidd, S.L]]		[[Category: Kidd, S.L]]
-	[[Category: Madin, A]]
-	[[Category: Fairhead, M]]
-	[[Category: Von Delft, F]]
	[[Category: Bradley, A.R]]		[[Category: Bradley, A.R]]
	[[Category: Talon, R]]		[[Category: Talon, R]]
	[[Category: Huber, K.V.M]]		[[Category: Huber, K.V.M]]
	[[Category: Sore, H.F]]		[[Category: Sore, H.F]]
		+	[[Category: Madin, A]]
	[[Category: Krojer, T]]		[[Category: Krojer, T]]
		+	[[Category: Fairhead, M]]
		+	[[Category: Von Delft, F]]

OCA: Protected "5r4s" [edit=sysop:move=sysop]

OCA — Wed, 04 Mar 2020 05:24:40 GMT

Protected "5r4s" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:24, 4 March 2020

OCA: New page: '''Unreleased structure''' The entry 5r4s is ON HOLD Authors: Kidd, S.L., Mateu, N., Talon, R., Krojer, T., Aimon, A., Bradley, A.R., Fairhead, M., DÃÆÃÆÃâÃÂaz...

OCA — Wed, 04 Mar 2020 05:24:39 GMT

New page: '''Unreleased structure''' The entry 5r4s is ON HOLD Authors: Kidd, S.L., Mateu, N., Talon, R., Krojer, T., Aimon, A., Bradley, A.R., Fairhead, M., DÃÆÃÆÃâÃÂaz...

New page

'''Unreleased structure'''

The entry 5r4s is ON HOLD

Authors: Kidd, S.L., Mateu, N., Talon, R., Krojer, T., Aimon, A., Bradley, A.R., Fairhead, M., DÃÆÃÆÃâÃÂaz-SÃÆÃÆÃâÃÂ¡ez, L., Sore, H.F., Madin, A., Huber, K.V.M., von Delft, F., Spring, D.R.

Description: PanDDA analysis group deposition --Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with EN08775-45
[[Category: Unreleased Structures]]
[[Category: Spring, D.R]]
[[Category: DãÆÃÆÃÂÃÂAz-SãÆÃÆÃÂÃÂ¡Ez, L]]
[[Category: Aimon, A]]
[[Category: Mateu, N]]
[[Category: Kidd, S.L]]
[[Category: Madin, A]]
[[Category: Fairhead, M]]
[[Category: Von Delft, F]]
[[Category: Bradley, A.R]]
[[Category: Talon, R]]
[[Category: Huber, K.V.M]]
[[Category: Sore, H.F]]
[[Category: Krojer, T]]