5s8e - Revision history

OCA at 14:16, 6 March 2024

OCA — Wed, 06 Mar 2024 14:16:46 GMT

←Older revision		Revision as of 14:16, 6 March 2024
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	==XChem group deposition -- Crystal Structure of the second bromodomain of pleckstrin homology domain interacting protein (PHIP) in complex with N00531b (space group C2)==		==XChem group deposition -- Crystal Structure of the second bromodomain of pleckstrin homology domain interacting protein (PHIP) in complex with N00531b (space group C2)==
-	<StructureSection load='5s8e' size='340' side='right'caption='[[5s8e]]' scene=''>	+	<StructureSection load='5s8e' size='340' side='right'caption='[[5s8e]], [[Resolution\|resolution]] 1.24Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5S8E OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5S8E FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5s8e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5S8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5S8E FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5s8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5s8e OCA], [~~http~~://pdbe.org/5s8e PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5s8e RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5s8e PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5s8e ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.24Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5WY:2,3-DIHYDRO-1,4-BENZODIOXINE-5-CARBOXAMIDE'>5WY</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5s8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5s8e OCA], [https://pdbe.org/5s8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5s8e RCSB], [https://www.ebi.ac.uk/pdbsum/5s8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5s8e ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PHIP_HUMAN PHIP_HUMAN] Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:12242307</ref> <ref>PMID:21834987</ref>
		+
		+	==See Also==
		+	*[[WD-repeat protein 3D structures\|WD-repeat protein 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Arrowsmith CH]]		[[Category: Arrowsmith CH]]

OCA at 05:45, 20 January 2021

OCA — Wed, 20 Jan 2021 05:45:49 GMT

←Older revision		Revision as of 05:45, 20 January 2021
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-	'''Unreleased structure'''

-	~~The entry 5s8e is ON HOLD~~	+	==XChem group deposition -- Crystal Structure of the second bromodomain of pleckstrin homology domain interacting protein (PHIP) in complex with N00531b (space group C2)==
-		+	<StructureSection load='5s8e' size='340' side='right'caption='[[5s8e]]' scene=''>
-	~~Authors: Krojer, T., Talon, R., Fairhead, M., Szykowska, A., Burgess-Brown, N.A., Brennan, P.E., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5S8E OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5S8E FirstGlance]. <br>
-	~~Description:~~ XChem group deposition --Crystal Structure of the second bromodomain of pleckstrin homology domain interacting protein (PHIP) in complex with N00531b (space group C2)	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5s8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5s8e OCA], [http://pdbe.org/5s8e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5s8e RCSB], [http://www.ebi.ac.uk/pdbsum/5s8e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5s8e ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Edwards~~, A.M]]	+	__TOC__
-	[[Category: ~~Arrowsmith, C.H~~]]	+	</StructureSection>
-	[[Category: ~~Talon, R~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Brennan, P.E~~]]	+	[[Category: Arrowsmith CH]]
-	[[Category: ~~Szykowska, A~~]]	+	[[Category: Bountra C]]
-	[[Category: Burgess-Brown~~, N.A~~]]	+	[[Category: Brennan PE]]
-	[[Category: ~~Krojer, T~~]]	+	[[Category: Burgess-Brown NA]]
-	[[Category: Fairhead, M]]	+	[[Category: Edwards AM]]
-	[[Category: ~~Von Delft, F~~]]	+	[[Category: Fairhead M]]
-	[[Category: ~~Bountra, C~~]]	+	[[Category: Krojer T]]
		+	[[Category: Szykowska A]]
		+	[[Category: Talon R]]
		+	[[Category: Von Delft F]]

OCA: Protected "5s8e" [edit=sysop:move=sysop]

OCA — Thu, 24 Dec 2020 07:30:07 GMT

Protected "5s8e" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:30, 24 December 2020

OCA: New page: '''Unreleased structure''' The entry 5s8e is ON HOLD Authors: Krojer, T., Talon, R., Fairhead, M., Szykowska, A., Burgess-Brown, N.A., Brennan, P.E., Arrowsmith, C.H., Edwards, A.M., Bo...

OCA — Thu, 24 Dec 2020 07:30:06 GMT

New page: '''Unreleased structure''' The entry 5s8e is ON HOLD Authors: Krojer, T., Talon, R., Fairhead, M., Szykowska, A., Burgess-Brown, N.A., Brennan, P.E., Arrowsmith, C.H., Edwards, A.M., Bo...

New page

'''Unreleased structure'''

The entry 5s8e is ON HOLD

Authors: Krojer, T., Talon, R., Fairhead, M., Szykowska, A., Burgess-Brown, N.A., Brennan, P.E., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F.

Description: XChem group deposition --Crystal Structure of the second bromodomain of pleckstrin homology domain interacting protein (PHIP) in complex with N00531b (space group C2)
[[Category: Unreleased Structures]]
[[Category: Edwards, A.M]]
[[Category: Arrowsmith, C.H]]
[[Category: Talon, R]]
[[Category: Brennan, P.E]]
[[Category: Szykowska, A]]
[[Category: Burgess-Brown, N.A]]
[[Category: Krojer, T]]
[[Category: Fairhead, M]]
[[Category: Von Delft, F]]
[[Category: Bountra, C]]