5t67 - Revision history

OCA at 12:55, 4 October 2023

OCA — Wed, 04 Oct 2023 12:55:10 GMT

←Older revision		Revision as of 12:55, 4 October 2023
Line 3:		Line 3:
	<StructureSection load='5t67' size='340' side='right'caption='[[5t67]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='5t67' size='340' side='right'caption='[[5t67]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5t67]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Actki Actki~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T67 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5T67 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5t67]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinomadura_kijaniata Actinomadura kijaniata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T67 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T67 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JHZ:(2R,4S,6R)-4-amino-4,6-dimethyl-5-oxotetrahydro-2H-pyran-2-yl+[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl+dihydrogen+diphosphate+(non-preferred+name)'>JHZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5t64\|5t64]], [[5t6b\|5t6b]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JHZ:(2R,4S,6R)-4-amino-4,6-dimethyl-5-oxotetrahydro-2H-pyran-2-yl+[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl+dihydrogen+diphosphate+(non-preferred+name)'>JHZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KijD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46161 ACTKI])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t67 OCA], [https://pdbe.org/5t67 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t67 RCSB], [https://www.ebi.ac.uk/pdbsum/5t67 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t67 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5t67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t67 OCA], [~~http~~://pdbe.org/5t67 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5t67 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5t67 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5t67 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B3TMQ9_ACTKI B3TMQ9_ACTKI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Actki~~]]	+	[[Category: Actinomadura kijaniata]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Dow~~, G T~~]]	+	[[Category: Dow GT]]
-	[[Category: Holden~~, H M~~]]	+	[[Category: Holden HM]]
-	[[Category: Thoden~~, J B]]~~	+	[[Category: Thoden JB]]
-	~~[[Category: Antibiotic]]~~	+
-	~~[[Category: Antitumor]]~~	+
-	~~[[Category: C3-methyltransferase]]~~	+
-	~~[[Category: Kijanimicin]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 12:28, 25 December 2019

OCA — Wed, 25 Dec 2019 12:28:42 GMT

←Older revision		Revision as of 12:28, 25 December 2019
Line 1:		Line 1:

	==x-ray structure of the KijD1 C3-methyltransferase from Actinomadura kijaniata in complex with SAH and dTDP-sugar product==		==x-ray structure of the KijD1 C3-methyltransferase from Actinomadura kijaniata in complex with SAH and dTDP-sugar product==
-	<StructureSection load='5t67' size='340' side='right' caption='[[5t67]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='5t67' size='340' side='right'caption='[[5t67]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5t67]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Atcc_31588 Atcc 31588~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T67 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T67 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5t67]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Actki Actki]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T67 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T67 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JHZ:(2R,4S,6R)-4-amino-4,6-dimethyl-5-oxotetrahydro-2H-pyran-2-yl+[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl+dihydrogen+diphosphate+(non-preferred+name)'>JHZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JHZ:(2R,4S,6R)-4-amino-4,6-dimethyl-5-oxotetrahydro-2H-pyran-2-yl+[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl+dihydrogen+diphosphate+(non-preferred+name)'>JHZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5t64\|5t64]], [[5t6b\|5t6b]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5t64\|5t64]], [[5t6b\|5t6b]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KijD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46161 ~~ATCC 31588~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KijD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46161 ACTKI])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t67 OCA], [http://pdbe.org/5t67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t67 RCSB], [http://www.ebi.ac.uk/pdbsum/5t67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t67 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t67 OCA], [http://pdbe.org/5t67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t67 RCSB], [http://www.ebi.ac.uk/pdbsum/5t67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t67 ProSAT]</span></td></tr>
	</table>		</table>
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 31588~~]]	+	[[Category: Actki]]
		+	[[Category: Large Structures]]
	[[Category: Dow, G T]]		[[Category: Dow, G T]]
	[[Category: Holden, H M]]		[[Category: Holden, H M]]

OCA at 14:21, 6 November 2017

OCA — Mon, 06 Nov 2017 14:21:28 GMT

←Older revision		Revision as of 14:21, 6 November 2017
Line 3:		Line 3:
	<StructureSection load='5t67' size='340' side='right' caption='[[5t67]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='5t67' size='340' side='right' caption='[[5t67]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5t67]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T67 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T67 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5t67]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_31588 Atcc 31588]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T67 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T67 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JHZ:(2R,4S,6R)-4-amino-4,6-dimethyl-5-oxotetrahydro-2H-pyran-2-yl+[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl+dihydrogen+diphosphate+(non-preferred+name)'>JHZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JHZ:(2R,4S,6R)-4-amino-4,6-dimethyl-5-oxotetrahydro-2H-pyran-2-yl+[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl+dihydrogen+diphosphate+(non-preferred+name)'>JHZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5t64\|5t64]], [[5t6b\|5t6b]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5t64\|5t64]], [[5t6b\|5t6b]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KijD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46161 ATCC 31588])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t67 OCA], [http://pdbe.org/5t67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t67 RCSB], [http://www.ebi.ac.uk/pdbsum/5t67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t67 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t67 OCA], [http://pdbe.org/5t67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t67 RCSB], [http://www.ebi.ac.uk/pdbsum/5t67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t67 ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 31588]]
	[[Category: Dow, G T]]		[[Category: Dow, G T]]
	[[Category: Holden, H M]]		[[Category: Holden, H M]]

OCA at 09:14, 3 October 2016

OCA — Mon, 03 Oct 2016 09:14:42 GMT

←Older revision		Revision as of 09:14, 3 October 2016
Line 1:		Line 1:

-	==x-ray structure of the KijD1 C3-methyltransferase from Actinomadura kijaniata in complex with ~~SAN~~ and dTDP-sugar product==	+	==x-ray structure of the KijD1 C3-methyltransferase from Actinomadura kijaniata in complex with SAH and dTDP-sugar product==
	<StructureSection load='5t67' size='340' side='right' caption='[[5t67]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='5t67' size='340' side='right' caption='[[5t67]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==

OCA at 06:37, 21 September 2016

OCA — Wed, 21 Sep 2016 06:37:45 GMT

←Older revision		Revision as of 06:37, 21 September 2016
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t67 OCA], [http://pdbe.org/5t67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t67 RCSB], [http://www.ebi.ac.uk/pdbsum/5t67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t67 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t67 OCA], [http://pdbe.org/5t67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t67 RCSB], [http://www.ebi.ac.uk/pdbsum/5t67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t67 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Kijanimicin is an antitumor antibiotic isolated from Actinomadura kijaniata. It is composed of three distinct moieties: a pentacyclic core, a monosaccharide referred to as d-kijanose, and a tetrasaccharide chain composed of l-digitoxose units. d-Kijanose is a highly unusual nitro-containing tetradeoxysugar, which requires at least ten enzymes for its production. Here we describe a structural analysis of one of these enzymes, namely KijD1, which functions as a C-3'-methyltransferase using S-adenosylmethionine as its cofactor. For this investigation, two ternary complexes of KijD1, determined in the presence of S-adenosylhomocysteine (SAH) and dTDP or SAH and dTDP-3-amino-2,3,6-trideoxy-4-keto-3-methyl-d-glucose, were solved to 1.7 or 1.6 A resolution, respectively. Unexpectedly, these structures, as well as additional biochemical analyses, demonstrated that the quaternary structure of KijD1 is a dimer. Indeed, this is in sharp contrast to that previously observed for the sugar C-3'-methyltransferase isolated from Micromonospora chalcea. By the judicious use of site-directed mutagenesis, it was possible to convert the dimeric form of KijD1 into a monomeric version. The quaternary structure of KijD1 could not have been deduced based solely on bioinformatics approaches, and thus this investigation highlights the continuing need for experimental validation.
		+
		+	Structural studies on KijD1, a sugar C-3'-methyltransferase.,Dow GT, Thoden JB, Holden HM Protein Sci. 2016 Sep 6. doi: 10.1002/pro.3034. PMID:27595766<ref>PMID:27595766</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5t67" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 15:38, 14 September 2016

OCA — Wed, 14 Sep 2016 15:38:08 GMT

←Older revision		Revision as of 15:38, 14 September 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 5t67 is ON HOLD~~	+	==x-ray structure of the KijD1 C3-methyltransferase from Actinomadura kijaniata in complex with SAN and dTDP-sugar product==
-		+	<StructureSection load='5t67' size='340' side='right' caption='[[5t67]], [[Resolution\|resolution]] 1.60Å' scene=''>
-	~~Authors: Holden, H.M., Thoden, J.B., Dow, G.T.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5t67]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T67 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T67 FirstGlance]. <br>
-	~~Description:~~ x-ray structure of the KijD1 C3-methyltransferase from Actinomadura kijaniata in complex with SAN and dTDP-sugar product	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JHZ:(2R,4S,6R)-4-amino-4,6-dimethyl-5-oxotetrahydro-2H-pyran-2-yl+[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl+dihydrogen+diphosphate+(non-preferred+name)'>JHZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5t64\|5t64]], [[5t6b\|5t6b]]</td></tr>
-	[[~~Category~~: ~~Thoden~~, J.B]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t67 OCA], [http://pdbe.org/5t67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t67 RCSB], [http://www.ebi.ac.uk/pdbsum/5t67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t67 ProSAT]</span></td></tr>
-	[[Category: Holden, H.M]]	+	</table>
-	[[Category: ~~Dow~~, ~~G.T~~]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Dow, G T]]
		+	[[Category: Holden, H M]]
		+	[[Category: Thoden, J B]]
		+	[[Category: Antibiotic]]
		+	[[Category: Antitumor]]
		+	[[Category: C3-methyltransferase]]
		+	[[Category: Kijanimicin]]
		+	[[Category: Transferase]]

OCA: Protected "5t67" [edit=sysop:move=sysop]

OCA — Fri, 09 Sep 2016 15:46:46 GMT

Protected "5t67" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:46, 9 September 2016

OCA: New page: '''Unreleased structure''' The entry 5t67 is ON HOLD Authors: Holden, H.M., Thoden, J.B., Dow, G.T. Description: x-ray structure of the KijD1 C3-methyltransferase from Actinomadura kij...

OCA — Fri, 09 Sep 2016 15:46:45 GMT

New page: '''Unreleased structure''' The entry 5t67 is ON HOLD Authors: Holden, H.M., Thoden, J.B., Dow, G.T. Description: x-ray structure of the KijD1 C3-methyltransferase from Actinomadura kij...

New page

'''Unreleased structure'''

The entry 5t67 is ON HOLD

Authors: Holden, H.M., Thoden, J.B., Dow, G.T.

Description: x-ray structure of the KijD1 C3-methyltransferase from Actinomadura kijaniata in complex with SAN and dTDP-sugar product
[[Category: Unreleased Structures]]
[[Category: Thoden, J.B]]
[[Category: Holden, H.M]]
[[Category: Dow, G.T]]