5tc9 - Revision history

OCA at 12:57, 4 October 2023

OCA — Wed, 04 Oct 2023 12:57:42 GMT

←Older revision		Revision as of 12:57, 4 October 2023
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	<StructureSection load='5tc9' size='340' side='right'caption='[[5tc9]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='5tc9' size='340' side='right'caption='[[5tc9]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5tc9]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Hypjq Hypjq~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TC9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5TC9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5tc9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichoderma_reesei_QM6a Trichoderma reesei QM6a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TC9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GD3:GADOLINIUM+ION'>GD3</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GD3:GADOLINIUM+ION'>GD3</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5tc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tc9 OCA], [~~http~~://pdbe.org/5tc9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5tc9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5tc9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5tc9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tc9 OCA], [https://pdbe.org/5tc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tc9 RCSB], [https://www.ebi.ac.uk/pdbsum/5tc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tc9 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/G0RVK1_HYPJQ G0RVK1_HYPJQ]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Hypjq]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bodenheimer, A M~~]]	+	[[Category: Trichoderma reesei QM6a]]
-	[[Category: ~~Meilleur, F~~]]	+	[[Category: Bodenheimer AM]]
-	[[Category: ~~Cbhi]]~~	+	[[Category: Meilleur F]]
-	~~[[Category: Cel7a]]~~	+
-	~~[[Category: Cellulase]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 07:52, 27 November 2019

OCA — Wed, 27 Nov 2019 07:52:04 GMT

←Older revision		Revision as of 07:52, 27 November 2019
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	==Wild type TrCel7A catalytic domain in a closed state==		==Wild type TrCel7A catalytic domain in a closed state==
-	<StructureSection load='5tc9' size='340' side='right' caption='[[5tc9]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='5tc9' size='340' side='right'caption='[[5tc9]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5tc9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hypjq Hypjq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TC9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[5tc9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hypjq Hypjq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TC9 FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 5tc9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5tc9" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cellobiohydrolase 3D structures\|Cellobiohydrolase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Hypjq]]		[[Category: Hypjq]]
		+	[[Category: Large Structures]]
	[[Category: Bodenheimer, A M]]		[[Category: Bodenheimer, A M]]
	[[Category: Meilleur, F]]		[[Category: Meilleur, F]]

OCA at 19:03, 15 November 2017

OCA — Wed, 15 Nov 2017 19:03:03 GMT

←Older revision		Revision as of 19:03, 15 November 2017
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	<StructureSection load='5tc9' size='340' side='right' caption='[[5tc9]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='5tc9' size='340' side='right' caption='[[5tc9]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5tc9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Hypocrea_jecorina_(strain_qm6a) Hypocrea jecorina (strain qm6a)~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TC9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5tc9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hypjq Hypjq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TC9 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GD3:GADOLINIUM+ION'>GD3</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GD3:GADOLINIUM+ION'>GD3</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Hypjq]]
	[[Category: Bodenheimer, A M]]		[[Category: Bodenheimer, A M]]
	[[Category: Meilleur, F]]		[[Category: Meilleur, F]]

OCA at 16:41, 4 January 2017

OCA — Wed, 04 Jan 2017 16:41:35 GMT

←Older revision		Revision as of 16:41, 4 January 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5tc9 is ~~ON HOLD until Paper~~ Publication	+	==Wild type TrCel7A catalytic domain in a closed state==
		+	<StructureSection load='5tc9' size='340' side='right' caption='[[5tc9]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5tc9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hypocrea_jecorina_(strain_qm6a) Hypocrea jecorina (strain qm6a)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TC9 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GD3:GADOLINIUM+ION'>GD3</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tc9 OCA], [http://pdbe.org/5tc9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tc9 RCSB], [http://www.ebi.ac.uk/pdbsum/5tc9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tc9 ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Trichoderma reesei Cel7A efficiently hydrolyses cellulose. We report here the crystallographic structures of the wild-type TrCel7A catalytic domain (CD) in an open state and, for the first time, in a closed state. Molecular dynamics (MD) simulations indicate that the loops along the CD tunnel move in concerted motions. Together, the crystallographic and MD data suggest that the CD cycles between the tense and relaxed forms that are characteristic of work producing enzymes. Analysis of the interactions formed by R251 provides a structural rationale for the concurrent decrease in product inhibition and catalytic efficiency measured for product-binding site mutants.

-	~~Authors~~:	+	Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states.,Bodenheimer AM, Meilleur F FEBS Lett. 2016 Dec;590(23):4429-4438. doi: 10.1002/1873-3468.12464. Epub 2016, Nov 7. PMID:27943301<ref>PMID:27943301</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5tc9" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bodenheimer, A M]]
		+	[[Category: Meilleur, F]]
		+	[[Category: Cbhi]]
		+	[[Category: Cel7a]]
		+	[[Category: Cellulase]]
		+	[[Category: Hydrolase]]

OCA at 16:54, 26 October 2016

OCA — Wed, 26 Oct 2016 16:54:50 GMT

←Older revision		Revision as of 16:54, 26 October 2016
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5tc9 is ON HOLD	+	The entry 5tc9 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 15:38, 19 October 2016

OCA — Wed, 19 Oct 2016 15:38:45 GMT

←Older revision		Revision as of 15:38, 19 October 2016
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5tc9 is ON HOLD ~~until Paper Publication~~	+	The entry 5tc9 is ON HOLD

	Authors:		Authors:

OCA at 19:54, 5 October 2016

OCA — Wed, 05 Oct 2016 19:54:24 GMT

←Older revision		Revision as of 19:54, 5 October 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5tc9 is ON HOLD	+	The entry 5tc9 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5tc9" [edit=sysop:move=sysop]

OCA — Wed, 21 Sep 2016 12:29:57 GMT

Protected "5tc9" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:29, 21 September 2016

OCA: New page: '''Unreleased structure''' The entry 5tc9 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 21 Sep 2016 12:29:56 GMT

New page: '''Unreleased structure''' The entry 5tc9 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5tc9 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]