5tkg - Revision history

OCA at 13:04, 4 October 2023

OCA — Wed, 04 Oct 2023 13:04:27 GMT

←Older revision		Revision as of 13:04, 4 October 2023
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	<StructureSection load='5tkg' size='340' side='right'caption='[[5tkg]], [[Resolution\|resolution]] 1.20Å' scene=''>		<StructureSection load='5tkg' size='340' side='right'caption='[[5tkg]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5tkg]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Chrysonilia_crassa Chrysonilia~~ crassa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TKG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5TKG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5tkg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Neurospora_crassa Neurospora crassa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TKG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TKG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.2Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5tki\|5tki]], [[5tkh\|5tkh]], [[5tkf\|5tkf]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">G15G9.090, GE21DRAFT_7469 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5141 Chrysonilia crassa])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tkg OCA], [https://pdbe.org/5tkg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tkg RCSB], [https://www.ebi.ac.uk/pdbsum/5tkg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tkg ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5tkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tkg OCA], [~~http~~://pdbe.org/5tkg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5tkg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5tkg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5tkg ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8WZQ2_NEUCS Q8WZQ2_NEUCS]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Chrysonilia crassa]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Dell, W B.O~~]]	+	[[Category: Neurospora crassa]]
-	[[Category: Meilleur, F]]	+	[[Category: Meilleur F]]
-	[[Category: ~~Oxidoreductase]]~~	+	[[Category: O'Dell WB]]
-	~~[[Category: Polysaccharide monooxygenase~~]]	+

OCA at 07:53, 27 November 2019

OCA — Wed, 27 Nov 2019 07:53:18 GMT

←Older revision		Revision as of 07:53, 27 November 2019
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	==Neurospora crassa polysaccharide monooxygenase 2 resting state==		==Neurospora crassa polysaccharide monooxygenase 2 resting state==
-	<StructureSection load='5tkg' size='340' side='right' caption='[[5tkg]], [[Resolution\|resolution]] 1.20Å' scene=''>	+	<StructureSection load='5tkg' size='340' side='right'caption='[[5tkg]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5tkg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chrysonilia_crassa Chrysonilia crassa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TKG FirstGlance]. <br>		<table><tr><td colspan='2'>[[5tkg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chrysonilia_crassa Chrysonilia crassa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TKG FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 5tkg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5tkg" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Monooxygenase 3D structures\|Monooxygenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Chrysonilia crassa]]		[[Category: Chrysonilia crassa]]
		+	[[Category: Large Structures]]
	[[Category: Dell, W B.O]]		[[Category: Dell, W B.O]]
	[[Category: Meilleur, F]]		[[Category: Meilleur, F]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Polysaccharide monooxygenase]]		[[Category: Polysaccharide monooxygenase]]

OCA at 19:13, 15 November 2017

OCA — Wed, 15 Nov 2017 19:13:17 GMT

←Older revision		Revision as of 19:13, 15 November 2017
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	<StructureSection load='5tkg' size='340' side='right' caption='[[5tkg]], [[Resolution\|resolution]] 1.20Å' scene=''>		<StructureSection load='5tkg' size='340' side='right' caption='[[5tkg]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5tkg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TKG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5tkg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chrysonilia_crassa Chrysonilia crassa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TKG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5tki\|5tki]], [[5tkh\|5tkh]], [[5tkf\|5tkf]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5tki\|5tki]], [[5tkh\|5tkh]], [[5tkf\|5tkf]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">G15G9.090, GE21DRAFT_7469 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5141 Chrysonilia crassa])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tkg OCA], [http://pdbe.org/5tkg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tkg RCSB], [http://www.ebi.ac.uk/pdbsum/5tkg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tkg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tkg OCA], [http://pdbe.org/5tkg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tkg RCSB], [http://www.ebi.ac.uk/pdbsum/5tkg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tkg ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chrysonilia crassa]]
	[[Category: Dell, W B.O]]		[[Category: Dell, W B.O]]
	[[Category: Meilleur, F]]		[[Category: Meilleur, F]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Polysaccharide monooxygenase]]		[[Category: Polysaccharide monooxygenase]]

OCA at 15:39, 17 May 2017

OCA — Wed, 17 May 2017 15:39:44 GMT

←Older revision		Revision as of 15:39, 17 May 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5tkg is ~~ON HOLD until Oct 06 2018~~	+	==Neurospora crassa polysaccharide monooxygenase 2 resting state==
		+	<StructureSection load='5tkg' size='340' side='right' caption='[[5tkg]], [[Resolution\|resolution]] 1.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5tkg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TKG FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5tki\|5tki]], [[5tkh\|5tkh]], [[5tkf\|5tkf]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tkg OCA], [http://pdbe.org/5tkg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tkg RCSB], [http://www.ebi.ac.uk/pdbsum/5tkg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tkg ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Lytic polysaccharide monooxygenases have attracted vast attention owing to their abilities to disrupt glycosidic bonds via oxidation instead of hydrolysis and to enhance enzymatic digestion of recalcitrant substrates including chitin and cellulose. We have determined high-resolution X-ray crystal structures of an enzyme from Neurospora crassa in the resting state and of a copper(II) dioxo intermediate complex formed in the absence of substrate. X-ray crystal structures also revealed "pre-bound" molecular oxygen adjacent to the active site. An examination of protonation states enabled by neutron crystallography and density functional theory calculations identified a role for a conserved histidine in promoting oxygen activation. These results provide a new structural description of oxygen activation by substrate free lytic polysaccharide monooxygenases and provide insights that can be extended to reactivity in the enzyme-substrate complex.

-	~~Authors:~~ O'Dell, ~~W.B.~~, Meilleur, F.	+	Oxygen Activation at the Active Site of a Fungal Lytic Polysaccharide Monooxygenase.,O'Dell WB, Agarwal PK, Meilleur F Angew Chem Int Ed Engl. 2017 Jan 16;56(3):767-770. doi: 10.1002/anie.201610502., Epub 2016 Dec 22. PMID:28004877<ref>PMID:28004877</ref>

-	~~Description~~: ~~Neurospora crassa polysaccharide monooxygenase 2 resting state~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5tkg" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Dell, W B.O]]
	[[Category: Meilleur, F]]		[[Category: Meilleur, F]]
-	[[Category: ~~O'Dell, W.B~~]]	+	[[Category: Oxidoreductase]]
		+	[[Category: Polysaccharide monooxygenase]]

OCA at 16:50, 2 November 2016

OCA — Wed, 02 Nov 2016 16:50:26 GMT

←Older revision		Revision as of 16:50, 2 November 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5tkg is ON HOLD	+	The entry 5tkg is ON HOLD until Oct 06 2018

	Authors: O'Dell, W.B., Meilleur, F.		Authors: O'Dell, W.B., Meilleur, F.

OCA: Protected "5tkg" [edit=sysop:move=sysop]

OCA — Wed, 19 Oct 2016 15:57:55 GMT

Protected "5tkg" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:57, 19 October 2016

OCA: New page: '''Unreleased structure''' The entry 5tkg is ON HOLD Authors: O'Dell, W.B., Meilleur, F. Description: Neurospora crassa polysaccharide monooxygenase 2 resting state [[Category: Unrelea...

OCA — Wed, 19 Oct 2016 15:57:53 GMT

New page: '''Unreleased structure''' The entry 5tkg is ON HOLD Authors: O'Dell, W.B., Meilleur, F. Description: Neurospora crassa polysaccharide monooxygenase 2 resting state [[Category: Unrelea...

New page

'''Unreleased structure'''

The entry 5tkg is ON HOLD

Authors: O'Dell, W.B., Meilleur, F.

Description: Neurospora crassa polysaccharide monooxygenase 2 resting state
[[Category: Unreleased Structures]]
[[Category: Meilleur, F]]
[[Category: O'Dell, W.B]]