5ts9 - Revision history

OCA at 13:09, 4 October 2023

OCA — Wed, 04 Oct 2023 13:09:56 GMT

←Older revision		Revision as of 13:09, 4 October 2023
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	==Crystal structure of Chorismate mutase from Burkholderia phymatum==		==Crystal structure of Chorismate mutase from Burkholderia phymatum==
-	<StructureSection load='5ts9' size='340' side='right' caption='[[5ts9]], [[Resolution\|resolution]] 1.95Å' scene=''>	+	<StructureSection load='5ts9' size='340' side='right'caption='[[5ts9]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ts9]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Burkholderia_phymatum Burkholderia~~ phymatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TS9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5TS9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ts9]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Paraburkholderia_phymatum_STM815 Paraburkholderia phymatum STM815]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TS9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TS9 FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~Bphy_7813 (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=391038 Burkholderia phymatum])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.95Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ts9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ts9 OCA], [~~http~~://pdbe.org/5ts9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5ts9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5ts9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5ts9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ts9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ts9 OCA], [https://pdbe.org/5ts9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ts9 RCSB], [https://www.ebi.ac.uk/pdbsum/5ts9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ts9 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B2JYH9_PARP8 B2JYH9_PARP8]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 5ts9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5ts9" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[3D structures of chorismate mutase\|3D structures of chorismate mutase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Burkholderia phymatum~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Structural genomic]]~~	+	[[Category: Paraburkholderia phymatum STM815]]
-	~~[[Category: Chorismate mutase]]~~	+
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Ssgcid~~]]	+

OCA at 05:53, 25 April 2018

OCA — Wed, 25 Apr 2018 05:53:06 GMT

←Older revision		Revision as of 05:53, 25 April 2018
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ts9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ts9 OCA], [http://pdbe.org/5ts9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ts9 RCSB], [http://www.ebi.ac.uk/pdbsum/5ts9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ts9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ts9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ts9 OCA], [http://pdbe.org/5ts9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ts9 RCSB], [http://www.ebi.ac.uk/pdbsum/5ts9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ts9 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The bacterium Burkholderia phymatum is a promiscuous symbiotic nitrogen-fixating bacterium that belongs to one of the largest groups of Betaproteobacteria. Other Burkholderia species are known to cause disease in plants and animals, and some are potential agents for biological warfare. Structural genomics efforts include characterizing the structures of enzymes from pathways that can be targeted for drug development. As part of these efforts, chorismate mutase from B. phymatum was produced and crystallized, and a 1.95 A resolution structure is reported. This enzyme shares less than 33% sequence identity with other homologs of known structure. There are two classes of chorismate mutase: AroQ and AroH. The bacterial subclass AroQgamma has reported roles in virulence. Chorismate mutase from B. phymatum has the prototypical AroQgamma topology and retains the characteristic chorismate mutase active site. This suggests that substrate-based chorismate mutase inhibitors will not be specific and are likely to affect beneficial bacteria such as B. phymatum.
		+
		+	Crystal structure of chorismate mutase from Burkholderia phymatum.,Asojo OA, Subramanian S, Abendroth J, Exley I, Lorimer DD, Edwards TE, Myler PJ Acta Crystallogr F Struct Biol Commun. 2018 Apr 1;74(Pt 4):187-192. doi:, 10.1107/S2053230X18002868. Epub 2018 Mar 22. PMID:29633965<ref>PMID:29633965</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5ts9" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:18, 22 November 2017

OCA — Wed, 22 Nov 2017 10:18:38 GMT

←Older revision		Revision as of 10:18, 22 November 2017
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	<StructureSection load='5ts9' size='340' side='right' caption='[[5ts9]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='5ts9' size='340' side='right' caption='[[5ts9]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ts9]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TS9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TS9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ts9]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_phymatum Burkholderia phymatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TS9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TS9 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ts9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ts9 OCA], [http://pdbe.org/5ts9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ts9 RCSB], [http://www.ebi.ac.uk/pdbsum/5ts9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ts9 ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Bphy_7813 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391038 Burkholderia phymatum])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ts9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ts9 OCA], [http://pdbe.org/5ts9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ts9 RCSB], [http://www.ebi.ac.uk/pdbsum/5ts9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ts9 ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Structural genomic]]
	[[Category: Burkholderia phymatum]]		[[Category: Burkholderia phymatum]]
		+	[[Category: Structural genomic]]
	[[Category: Chorismate mutase]]		[[Category: Chorismate mutase]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
	[[Category: Ssgcid]]		[[Category: Ssgcid]]

OCA: Protected "5ts9" [edit=sysop:move=sysop]

OCA — Sat, 10 Dec 2016 10:59:35 GMT

Protected "5ts9" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:59, 10 December 2016

OCA: New page: ==Crystal structure of Chorismate mutase from Burkholderia phymatum==
OCA — Sat, 10 Dec 2016 10:59:32 GMT

New page: ==Crystal structure of Chorismate mutase from Burkholderia phymatum== <StructureSection load='5ts9' size='340' side='right' caption='5ts9, resolution 1.95Å' scene...

New page

==Crystal structure of Chorismate mutase from Burkholderia phymatum==
<StructureSection load='5ts9' size='340' side='right' caption='[[5ts9]], [[Resolution|resolution]] 1.95Å' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5ts9]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TS9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TS9 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ts9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ts9 OCA], [http://pdbe.org/5ts9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ts9 RCSB], [http://www.ebi.ac.uk/pdbsum/5ts9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ts9 ProSAT]</span></td></tr>
</table>
TOC
</StructureSection>
[[Category: Structural genomic]]
[[Category: Burkholderia phymatum]]
[[Category: Chorismate mutase]]
[[Category: Isomerase]]
[[Category: Ssgcid]]