5tvz - Revision history

OCA at 10:25, 14 June 2023

OCA — Wed, 14 Jun 2023 10:25:18 GMT

←Older revision		Revision as of 10:25, 14 June 2023
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	==Solution NMR structure of Saccharomyces cerevisiae Pom152 Ig-like repeat, residues 718-820==		==Solution NMR structure of Saccharomyces cerevisiae Pom152 Ig-like repeat, residues 718-820==
-	<StructureSection load='5tvz' size='340' side='right'caption='[[5tvz~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='5tvz' size='340' side='right'caption='[[5tvz]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5tvz]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TVZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5TVZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5tvz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TVZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TVZ FirstGlance]. <br>
-	</td></tr>~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POM152 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tvz OCA], [https://pdbe.org/5tvz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tvz RCSB], [https://www.ebi.ac.uk/pdbsum/5tvz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tvz ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5tvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tvz OCA], [~~http~~://pdbe.org/5tvz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5tvz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5tvz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5tvz ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PO152_YEAST PO152_YEAST]] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. POM152 is important for the de novo assembly of NPCs.<ref>PMID:11352933</ref> <ref>PMID:8682855</ref> <ref>PMID:9988776</ref>	+	[https://www.uniprot.org/uniprot/PO152_YEAST PO152_YEAST] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. POM152 is important for the de novo assembly of NPCs.<ref>PMID:11352933</ref> <ref>PMID:8682855</ref> <ref>PMID:9988776</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Almo~~, S C~~]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: Cowburn, D]]	+	[[Category: Almo SC]]
-	[[Category: Dutta, K]]	+	[[Category: Cowburn D]]
-	[[Category: Fernandez-Martinez, J]]	+	[[Category: Dutta K]]
-	[[Category: Rout~~, M P~~]]	+	[[Category: Fernandez-Martinez J]]
-	[[Category: Sampathkumar, P]]	+	[[Category: Rout MP]]
-	~~[[Category: Cadherin like fold]]~~	+	[[Category: Sampathkumar P]]
-	~~[[Category: Ig-like fold]]~~	+
-	~~[[Category: Nuclear envelope membrane]]~~	+
-	~~[[Category: Nuclear pore complex]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 09:06, 1 January 2020

OCA — Wed, 01 Jan 2020 09:06:46 GMT

←Older revision		Revision as of 09:06, 1 January 2020
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	==Solution NMR structure of Saccharomyces cerevisiae Pom152 Ig-like repeat, residues 718-820==		==Solution NMR structure of Saccharomyces cerevisiae Pom152 Ig-like repeat, residues 718-820==
-	<StructureSection load='5tvz' size='340' side='right' caption='[[5tvz]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='5tvz' size='340' side='right'caption='[[5tvz]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5tvz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TVZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TVZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[5tvz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TVZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TVZ FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 5tvz" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5tvz" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Nucleoporin 3D structures\|Nucleoporin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]
	[[Category: Cowburn, D]]		[[Category: Cowburn, D]]

OCA at 14:28, 6 November 2017

OCA — Mon, 06 Nov 2017 14:28:08 GMT

←Older revision		Revision as of 14:28, 6 November 2017
Line 3:		Line 3:
	<StructureSection load='5tvz' size='340' side='right' caption='[[5tvz]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='5tvz' size='340' side='right' caption='[[5tvz]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5tvz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TVZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TVZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5tvz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TVZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TVZ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tvz OCA], [http://pdbe.org/5tvz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tvz RCSB], [http://www.ebi.ac.uk/pdbsum/5tvz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tvz ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POM152 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tvz OCA], [http://pdbe.org/5tvz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tvz RCSB], [http://www.ebi.ac.uk/pdbsum/5tvz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tvz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 18824]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]
	[[Category: Cowburn, D]]		[[Category: Cowburn, D]]

OCA at 01:42, 11 March 2017

OCA — Sat, 11 Mar 2017 01:42:40 GMT

←Older revision		Revision as of 01:42, 11 March 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5tvz is ~~ON HOLD~~ ~~until Paper~~ Publication	+	==Solution NMR structure of Saccharomyces cerevisiae Pom152 Ig-like repeat, residues 718-820==
		+	<StructureSection load='5tvz' size='340' side='right' caption='[[5tvz]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5tvz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TVZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TVZ FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tvz OCA], [http://pdbe.org/5tvz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tvz RCSB], [http://www.ebi.ac.uk/pdbsum/5tvz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tvz ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PO152_YEAST PO152_YEAST]] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. POM152 is important for the de novo assembly of NPCs.<ref>PMID:11352933</ref> <ref>PMID:8682855</ref> <ref>PMID:9988776</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The membrane ring that equatorially circumscribes the nuclear pore complex (NPC) in the perinuclear lumen of the nuclear envelope is composed largely of Pom152 in yeast and its ortholog Nup210 (or Gp210) in vertebrates. Here, we have used a combination of negative-stain electron microscopy, nuclear magnetic resonance, and small-angle X-ray scattering methods to determine an integrative structure of the approximately 120 kDa luminal domain of Pom152. Our structural analysis reveals that the luminal domain is formed by a flexible string-of-pearls arrangement of nine repetitive cadherin-like Ig-like domains, indicating an evolutionary connection between NPCs and the cell adhesion machinery. The 16 copies of Pom152 known to be present in the yeast NPC are long enough to form the observed membrane ring, suggesting how interactions between Pom152 molecules help establish and maintain the NPC architecture.

-	~~Authors~~:	+	Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.,Upla P, Kim SJ, Sampathkumar P, Dutta K, Cahill SM, Chemmama IE, Williams R, Bonanno JB, Rice WJ, Stokes DL, Cowburn D, Almo SC, Sali A, Rout MP, Fernandez-Martinez J Structure. 2017 Mar 7;25(3):434-445. doi: 10.1016/j.str.2017.01.006. Epub 2017, Feb 2. PMID:28162953<ref>PMID:28162953</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5tvz" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Almo, S C]]
		+	[[Category: Cowburn, D]]
		+	[[Category: Dutta, K]]
		+	[[Category: Fernandez-Martinez, J]]
		+	[[Category: Rout, M P]]
		+	[[Category: Sampathkumar, P]]
		+	[[Category: Cadherin like fold]]
		+	[[Category: Ig-like fold]]
		+	[[Category: Nuclear envelope membrane]]
		+	[[Category: Nuclear pore complex]]
		+	[[Category: Transport protein]]

OCA: Protected "5tvz" [edit=sysop:move=sysop]

OCA — Fri, 09 Dec 2016 17:57:39 GMT

Protected "5tvz" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:57, 9 December 2016

OCA: New page: '''Unreleased structure''' The entry 5tvz is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

OCA — Fri, 09 Dec 2016 17:57:38 GMT

New page: '''Unreleased structure''' The entry 5tvz is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5tvz is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]