5u3h - Revision history

OCA at 10:25, 14 June 2023

OCA — Wed, 14 Jun 2023 10:25:20 GMT

←Older revision		Revision as of 10:25, 14 June 2023
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	==Solution structure of apo PCP1 from yersiniabactin synthetase==		==Solution structure of apo PCP1 from yersiniabactin synthetase==
-	<StructureSection load='5u3h' size='340' side='right'caption='[[5u3h~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='5u3h' size='340' side='right'caption='[[5u3h]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5u3h]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus~~ pestis~~" (lehmann and neumann 1896) migula 1900~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3H OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5U3H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5u3h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U3H FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">irp2, y2399, YPO1911 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 "Bacillus pestis" (Lehmann and Neumann 1896) Migula 1900])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u3h OCA], [https://pdbe.org/5u3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u3h RCSB], [https://www.ebi.ac.uk/pdbsum/5u3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u3h ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5u3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u3h OCA], [~~http~~://pdbe.org/5u3h PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5u3h RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5u3h PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5u3h ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A3N4B635_YERPE A0A3N4B635_YERPE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Frueh, D P~~]]	+	[[Category: Yersinia pestis]]
-	[[Category: ~~Harden, B J~~]]	+	[[Category: Frueh DP]]
-	[[Category: ~~Ligase]]~~	+	[[Category: Harden BJ]]
-	~~[[Category: Nrp]]~~	+
-	~~[[Category: Peptidyl carrier protein~~]]	+

OCA at 09:10, 1 January 2020

OCA — Wed, 01 Jan 2020 09:10:43 GMT

←Older revision		Revision as of 09:10, 1 January 2020
Line 1:		Line 1:

	==Solution structure of apo PCP1 from yersiniabactin synthetase==		==Solution structure of apo PCP1 from yersiniabactin synthetase==
-	<StructureSection load='5u3h' size='340' side='right' caption='[[5u3h]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='5u3h' size='340' side='right'caption='[[5u3h]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5u3h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U3H FirstGlance]. <br>		<table><tr><td colspan='2'>[[5u3h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U3H FirstGlance]. <br>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Frueh, D P]]		[[Category: Frueh, D P]]
	[[Category: Harden, B J]]		[[Category: Harden, B J]]

OCA at 14:30, 6 November 2017

OCA — Mon, 06 Nov 2017 14:30:15 GMT

←Older revision		Revision as of 14:30, 6 November 2017
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	<StructureSection load='5u3h' size='340' side='right' caption='[[5u3h]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='5u3h' size='340' side='right' caption='[[5u3h]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5u3h]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U3H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5u3h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U3H FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u3h OCA], [http://pdbe.org/5u3h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u3h RCSB], [http://www.ebi.ac.uk/pdbsum/5u3h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u3h ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">irp2, y2399, YPO1911 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 "Bacillus pestis" (Lehmann and Neumann 1896) Migula 1900])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u3h OCA], [http://pdbe.org/5u3h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u3h RCSB], [http://www.ebi.ac.uk/pdbsum/5u3h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u3h ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:29, 10 March 2017

OCA — Fri, 10 Mar 2017 09:29:41 GMT

←Older revision		Revision as of 09:29, 10 March 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5u3h is ~~ON HOLD until Paper~~ Publication	+	==Solution structure of apo PCP1 from yersiniabactin synthetase==
		+	<StructureSection load='5u3h' size='340' side='right' caption='[[5u3h]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5u3h]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U3H FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u3h OCA], [http://pdbe.org/5u3h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u3h RCSB], [http://www.ebi.ac.uk/pdbsum/5u3h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u3h ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Nonribosomal peptide synthetases (NRPSs) employ multiple domains separated by linker regions to incorporate substrates into natural products. During synthesis, substrates are covalently tethered to carrier proteins that translocate between catalytic partner domains. The molecular parameters that govern translocation and associated linker remodeling remain unknown. Here, we used NMR to characterize the structure, dynamics, and invisible states of a peptidyl carrier protein flanked by its linkers. We showed that the N-terminal linker stabilizes and interacts with the protein core while modulating dynamics at specific sites involved in post-translational modifications and/or domain interactions. The results detail the molecular communication between peptidyl carrier proteins and their linkers and could guide efforts in engineering NRPSs to obtain new pharmaceuticals.

-	~~Authors~~:	+	Molecular Cross-Talk between Nonribosomal Peptide Synthetase Carrier Proteins and Unstructured Linker Regions.,Harden BJ, Frueh DP Chembiochem. 2017 Jan 24. doi: 10.1002/cbic.201700030. PMID:28120469<ref>PMID:28120469</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5u3h" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Frueh, D P]]
		+	[[Category: Harden, B J]]
		+	[[Category: Ligase]]
		+	[[Category: Nrp]]
		+	[[Category: Peptidyl carrier protein]]

OCA at 15:02, 2 January 2017

OCA — Mon, 02 Jan 2017 15:02:07 GMT

←Older revision		Revision as of 15:02, 2 January 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5u3h is ON HOLD	+	The entry 5u3h is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5u3h" [edit=sysop:move=sysop]

OCA — Thu, 15 Dec 2016 17:37:15 GMT

Protected "5u3h" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:37, 15 December 2016

OCA: New page: '''Unreleased structure''' The entry 5u3h is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Thu, 15 Dec 2016 17:37:14 GMT

New page: '''Unreleased structure''' The entry 5u3h is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5u3h is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]