5u3x - Revision history

OCA at 13:19, 4 October 2023

OCA — Wed, 04 Oct 2023 13:19:40 GMT

←Older revision		Revision as of 13:19, 4 October 2023
Line 3:		Line 3:
	<StructureSection load='5u3x' size='340' side='right'caption='[[5u3x]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='5u3x' size='340' side='right'caption='[[5u3x]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5u3x]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3X OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5U3X FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5u3x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U3X FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7U4:6-[2-({CYCLOPROPYL[4-(PYRIDIN-3-YL)BENZENE-1-CARBONYL]AMINO}METHYL)PHENOXY]HEXANOIC+ACID'>7U4</scene>, <scene name='pdbligand=B7G:HEPTYL-BETA-D-GLUCOPYRANOSIDE'>B7G</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5u3q\|5u3q]], [[5u3r\|5u3r]], [[5u3s\|5u3s]], [[5u3t\|5u3t]], [[5u3u\|5u3u]], [[5u3v\|5u3v]], [[5u3w\|5u3w]], [[5u3y\|5u3y]], [[5u3z\|5u3z]], [[5u40\|5u40]], [[5u41\|5u41]], [[5u42\|5u42]], [[5u44\|5u44]], [[5u45\|5u45]], [[5u46\|5u46]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7U4:6-[2-({CYCLOPROPYL[4-(PYRIDIN-3-YL)BENZENE-1-CARBONYL]AMINO}METHYL)PHENOXY]HEXANOIC+ACID'>7U4</scene>, <scene name='pdbligand=B7G:HEPTYL-BETA-D-GLUCOPYRANOSIDE'>B7G</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PPARD, NR1C2, PPARB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u3x OCA], [https://pdbe.org/5u3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u3x RCSB], [https://www.ebi.ac.uk/pdbsum/5u3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u3x ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5u3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u3x OCA], [~~http~~://pdbe.org/5u3x PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5u3x RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5u3x PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5u3x ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PPARD_HUMAN PPARD_HUMAN]] Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.<ref>PMID:1333051</ref> <ref>PMID:15604518</ref>	+	[https://www.uniprot.org/uniprot/PPARD_HUMAN PPARD_HUMAN] Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.<ref>PMID:1333051</ref> <ref>PMID:15604518</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Atkins~~, A R~~]]	+	[[Category: Atkins AR]]
-	[[Category: Baiga~~, T J~~]]	+	[[Category: Baiga TJ]]
-	[[Category: Bowman~~, M E~~]]	+	[[Category: Bowman ME]]
-	[[Category: ~~Clair, J J.La~~]]	+	[[Category: Downes M]]
-	[[Category: ~~Downes, M~~]]	+	[[Category: Evans RM]]
-	[[Category: ~~Evans, R M~~]]	+	[[Category: La Clair JJ]]
-	[[Category: Noel~~, J P~~]]	+	[[Category: Noel JP]]
-	[[Category: Richard~~, S B~~]]	+	[[Category: Richard SB]]
-	[[Category: Stockley-Noel~~, T A~~]]	+	[[Category: Stockley-Noel TA]]
-	[[Category: Wu, C C]]	+	[[Category: Wu C-C]]
-	~~[[Category: Agonist]]~~	+
-	~~[[Category: Ligand-binding domain]]~~	+
-	~~[[Category: Ppardelta]]~~	+
-	~~[[Category: Protein binding-activator complex~~]]	+

OCA at 12:26, 23 September 2020

OCA — Wed, 23 Sep 2020 12:26:07 GMT

←Older revision		Revision as of 12:26, 23 September 2020
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	==Human PPARdelta ligand-binding domain in complexed with specific agonist 8==		==Human PPARdelta ligand-binding domain in complexed with specific agonist 8==
-	<StructureSection load='5u3x' size='340' side='right' caption='[[5u3x]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='5u3x' size='340' side='right'caption='[[5u3x]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5u3x]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3X OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5U3X FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5u3x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3X OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5U3X FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7U4:6-[2-({CYCLOPROPYL[4-(PYRIDIN-3-YL)BENZENE-1-CARBONYL]AMINO}METHYL)PHENOXY]HEXANOIC+ACID'>7U4</scene>, <scene name='pdbligand=B7G:HEPTYL-BETA-D-GLUCOPYRANOSIDE'>B7G</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7U4:6-[2-({CYCLOPROPYL[4-(PYRIDIN-3-YL)BENZENE-1-CARBONYL]AMINO}METHYL)PHENOXY]HEXANOIC+ACID'>7U4</scene>, <scene name='pdbligand=B7G:HEPTYL-BETA-D-GLUCOPYRANOSIDE'>B7G</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5u3q\|5u3q]], [[5u3r\|5u3r]], [[5u3s\|5u3s]], [[5u3t\|5u3t]], [[5u3u\|5u3u]], [[5u3v\|5u3v]], [[5u3w\|5u3w]], [[5u3y\|5u3y]], [[5u3z\|5u3z]], [[5u40\|5u40]], [[5u41\|5u41]], [[5u42\|5u42]], [[5u44\|5u44]], [[5u45\|5u45]], [[5u46\|5u46]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5u3q\|5u3q]], [[5u3r\|5u3r]], [[5u3s\|5u3s]], [[5u3t\|5u3t]], [[5u3u\|5u3u]], [[5u3v\|5u3v]], [[5u3w\|5u3w]], [[5u3y\|5u3y]], [[5u3z\|5u3z]], [[5u40\|5u40]], [[5u41\|5u41]], [[5u42\|5u42]], [[5u44\|5u44]], [[5u45\|5u45]], [[5u46\|5u46]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5u3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u3x OCA], [http://pdbe.org/5u3x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u3x RCSB], [http://www.ebi.ac.uk/pdbsum/5u3x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u3x ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PPARD, NR1C2, PPARB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5u3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u3x OCA], [http://pdbe.org/5u3x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u3x RCSB], [http://www.ebi.ac.uk/pdbsum/5u3x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u3x ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 5u3x" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5u3x" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Peroxisome proliferator-activated receptor 3D structures\|Peroxisome proliferator-activated receptor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Atkins, A R]]		[[Category: Atkins, A R]]
	[[Category: Baiga, T J]]		[[Category: Baiga, T J]]

OCA at 07:03, 29 March 2017

OCA — Wed, 29 Mar 2017 07:03:20 GMT

←Older revision		Revision as of 07:03, 29 March 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5u3x is ~~ON HOLD~~ ~~until Paper~~ Publication	+	==Human PPARdelta ligand-binding domain in complexed with specific agonist 8==
		+	<StructureSection load='5u3x' size='340' side='right' caption='[[5u3x]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5u3x]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U3X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U3X FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7U4:6-[2-({CYCLOPROPYL[4-(PYRIDIN-3-YL)BENZENE-1-CARBONYL]AMINO}METHYL)PHENOXY]HEXANOIC+ACID'>7U4</scene>, <scene name='pdbligand=B7G:HEPTYL-BETA-D-GLUCOPYRANOSIDE'>B7G</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5u3q\|5u3q]], [[5u3r\|5u3r]], [[5u3s\|5u3s]], [[5u3t\|5u3t]], [[5u3u\|5u3u]], [[5u3v\|5u3v]], [[5u3w\|5u3w]], [[5u3y\|5u3y]], [[5u3z\|5u3z]], [[5u40\|5u40]], [[5u41\|5u41]], [[5u42\|5u42]], [[5u44\|5u44]], [[5u45\|5u45]], [[5u46\|5u46]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u3x OCA], [http://pdbe.org/5u3x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u3x RCSB], [http://www.ebi.ac.uk/pdbsum/5u3x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u3x ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PPARD_HUMAN PPARD_HUMAN]] Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.<ref>PMID:1333051</ref> <ref>PMID:15604518</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The peroxisome proliferator-activated receptor (PPAR) family comprises three subtypes: PPARalpha, PPARgamma, and PPARdelta. PPARdelta transcriptionally modulates lipid metabolism and the control of energy homeostasis; therefore, PPARdelta agonists are promising agents for treating a variety of metabolic disorders. In the present study, we develop a panel of rationally designed PPARdelta agonists. The modular motif affords efficient syntheses using building blocks optimized for interactions with subtype-specific residues in the PPARdelta ligand-binding domain (LBD). A combination of atomic-resolution protein X-ray crystallographic structures, ligand-dependent LBD stabilization assays, and cell-based transactivation measurements delineate structure-activity relationships (SARs) for PPARdelta-selective targeting and structural modulation. We identify key ligand-induced conformational transitions of a conserved tryptophan side chain in the LBD that trigger reorganization of the H2'-H3 surface segment of PPARdelta. The subtype-specific conservation of H2'-H3 sequences suggests that this architectural remodeling constitutes a previously unrecognized conformational switch accompanying ligand-dependent PPARdelta transcriptional regulation.

-	~~Authors: Wu, C.~~-C., Baiga~~, T.J.~~, Downes, M. , La Clair~~, J.J.~~, Atkins~~, A.R.~~, Richard, ~~S.B.~~, Stockley-Noel~~, T.A.~~, Bowman, ~~M.E.~~, Evans~~, R~~.M., ~~Noel, J~~.P.	+	Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.,Wu CC, Baiga TJ, Downes M, La Clair JJ, Atkins AR, Richard SB, Fan W, Stockley-Noel TA, Bowman ME, Noel JP, Evans RM Proc Natl Acad Sci U S A. 2017 Mar 20. pii: 201621513. doi:, 10.1073/pnas.1621513114. PMID:28320959<ref>PMID:28320959</ref>

-	~~Description: Human PPARdelta ligand~~-~~binding domain in complexed with specific agonist 8~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
-	[[Category: Wu, C.-C]]	+	<div class="pdbe-citations 5u3x" style="background-color:#fffaf0;"></div>
-	[[Category: Noel, J.P]]	+	== References ==
-	[[Category: Richard, S.B]]	+	<references/>
-	[[Category: ~~Atkins~~, A.R]]	+	__TOC__
-	[[Category: ~~Baiga~~, ~~T.J~~]]	+	</StructureSection>
-	[[Category: ~~Bowman, M.E~~]]	+	[[Category: Atkins, A R]]
-	[[Category: ~~Evans, R.M~~]]	+	[[Category: Baiga, T J]]
-	[[Category: ~~Downes, M. , La Clair, J.J~~]]	+	[[Category: Bowman, M E]]
-	[[Category: ~~Stockley~~-~~Noel, T.A~~]]	+	[[Category: Clair, J J.La]]
		+	[[Category: Downes, M]]
		+	[[Category: Evans, R M]]
		+	[[Category: Noel, J P]]
		+	[[Category: Richard, S B]]
		+	[[Category: Stockley-Noel, T A]]
		+	[[Category: Wu, C C]]
		+	[[Category: Agonist]]
		+	[[Category: Ligand-binding domain]]
		+	[[Category: Ppardelta]]
		+	[[Category: Protein binding-activator complex]]

OCA at 13:59, 9 March 2017

OCA — Thu, 09 Mar 2017 13:59:42 GMT

←Older revision		Revision as of 13:59, 9 March 2017
Line 8:		Line 8:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Wu, C.-C]]		[[Category: Wu, C.-C]]
		+	[[Category: Noel, J.P]]
	[[Category: Richard, S.B]]		[[Category: Richard, S.B]]
	[[Category: Atkins, A.R]]		[[Category: Atkins, A.R]]
		+	[[Category: Baiga, T.J]]
	[[Category: Bowman, M.E]]		[[Category: Bowman, M.E]]
	[[Category: Evans, R.M]]		[[Category: Evans, R.M]]
-	[[Category: Noel, J.P]]
-	[[Category: Baiga, T.J]]
	[[Category: Downes, M. , La Clair, J.J]]		[[Category: Downes, M. , La Clair, J.J]]
	[[Category: Stockley-Noel, T.A]]		[[Category: Stockley-Noel, T.A]]

OCA at 15:02, 2 January 2017

OCA — Mon, 02 Jan 2017 15:02:56 GMT

←Older revision		Revision as of 15:02, 2 January 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5u3x is ON HOLD	+	The entry 5u3x is ON HOLD until Paper Publication

	Authors: Wu, C.-C., Baiga, T.J., Downes, M. , La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.		Authors: Wu, C.-C., Baiga, T.J., Downes, M. , La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.

OCA: Protected "5u3x" [edit=sysop:move=sysop]

OCA — Thu, 15 Dec 2016 17:38:39 GMT

Protected "5u3x" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:38, 15 December 2016

OCA: New page: '''Unreleased structure''' The entry 5u3x is ON HOLD Authors: Wu, C.-C., Baiga, T.J., Downes, M. , La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans,...

OCA — Thu, 15 Dec 2016 17:38:38 GMT

New page: '''Unreleased structure''' The entry 5u3x is ON HOLD Authors: Wu, C.-C., Baiga, T.J., Downes, M. , La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans,...

New page

'''Unreleased structure'''

The entry 5u3x is ON HOLD

Authors: Wu, C.-C., Baiga, T.J., Downes, M. , La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.

Description: Human PPARdelta ligand-binding domain in complexed with specific agonist 8
[[Category: Unreleased Structures]]
[[Category: Wu, C.-C]]
[[Category: Richard, S.B]]
[[Category: Atkins, A.R]]
[[Category: Bowman, M.E]]
[[Category: Evans, R.M]]
[[Category: Noel, J.P]]
[[Category: Baiga, T.J]]
[[Category: Downes, M. , La Clair, J.J]]
[[Category: Stockley-Noel, T.A]]