5ucy - Revision history

OCA at 21:53, 10 April 2020

OCA — Fri, 10 Apr 2020 21:53:32 GMT

←Older revision		Revision as of 21:53, 10 April 2020
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	<SX load='5ucy' size='340' side='right' viewer='molstar' caption='[[5ucy]], [[Resolution\|resolution]] 4.60Å' scene=''>		<SX load='5ucy' size='340' side='right' viewer='molstar' caption='[[5ucy]], [[Resolution\|resolution]] 4.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ucy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UCY OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5UCY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ucy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UCY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5UCY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ubq\|5ubq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ubq\|5ubq]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ucy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ucy OCA], [http://pdbe.org/5ucy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ucy RCSB], [http://www.ebi.ac.uk/pdbsum/5ucy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ucy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ucy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ucy OCA], [http://pdbe.org/5ucy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ucy RCSB], [http://www.ebi.ac.uk/pdbsum/5ucy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ucy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[Tubulin\|Tubulin]]	+	*[[Tubulin 3D Structures\|Tubulin 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 19:42, 6 March 2020

OCA — Fri, 06 Mar 2020 19:42:42 GMT

←Older revision		Revision as of 19:42, 6 March 2020
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	==Cryo-EM map of protofilament of microtubule doublet==		==Cryo-EM map of protofilament of microtubule doublet==
-	<~~StructureSection~~ load='5ucy' size='340' side='right' caption='[[5ucy]], [[Resolution\|resolution]] 4.60Å' scene=''>	+	<SX load='5ucy' size='340' side='right' viewer='molstar' caption='[[5ucy]], [[Resolution\|resolution]] 4.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5ucy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UCY FirstGlance]. <br>		<table><tr><td colspan='2'>[[5ucy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UCY FirstGlance]. <br>
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	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
		+	[[Category: Large Structures]]
	[[Category: Tetrahymena thermophila]]		[[Category: Tetrahymena thermophila]]
	[[Category: Basu, K]]		[[Category: Basu, K]]

OCA at 05:52, 16 May 2018

OCA — Wed, 16 May 2018 05:52:20 GMT

←Older revision		Revision as of 05:52, 16 May 2018
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	</div>		</div>
	<div class="pdbe-citations 5ucy" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5ucy" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Tubulin\|Tubulin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:03, 17 May 2017

OCA — Wed, 17 May 2017 09:03:49 GMT

←Older revision		Revision as of 09:03, 17 May 2017
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	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/TBA_TETTH TBA_TETTH]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/TBB_TETTH TBB_TETTH]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.		[[http://www.uniprot.org/uniprot/TBA_TETTH TBA_TETTH]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/TBB_TETTH TBB_TETTH]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cilia are ubiquitous, hair-like appendages found in eukaryotic cells that carry out functions of cell motility and sensory reception. Cilia contain an intriguing cytoskeletal structure, termed the axoneme that consists of nine doublet microtubules radially interlinked and longitudinally organized in multiple specific repeat units. Little is known, however, about how the axoneme allows cilia to be both actively bendable and sturdy or how it is assembled. To answer these questions, we used cryo-electron microscopy to structurally analyse several of the repeating units of the doublet at sub-nanometre resolution. This structural detail enables us to unambiguously assign alpha- and beta-tubulins in the doublet microtubule lattice. Our study demonstrates the existence of an inner sheath composed of different kinds of microtubule inner proteins inside the doublet that likely stabilizes the structure and facilitates the specific building of the B-tubule.
		+
		+	Subnanometre-resolution structure of the doublet microtubule reveals new classes of microtubule-associated proteins.,Ichikawa M, Liu D, Kastritis PL, Basu K, Hsu TC, Yang S, Bui KH Nat Commun. 2017 May 2;8:15035. doi: 10.1038/ncomms15035. PMID:28462916<ref>PMID:28462916</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5ucy" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 13:01, 10 May 2017

OCA — Wed, 10 May 2017 13:01:09 GMT

←Older revision		Revision as of 13:01, 10 May 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5ucy is ~~ON HOLD until Paper Publication~~	+	==Cryo-EM map of protofilament of microtubule doublet==
-		+	<StructureSection load='5ucy' size='340' side='right' caption='[[5ucy]], [[Resolution\|resolution]] 4.60Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5ucy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UCY FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ubq\|5ubq]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ucy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ucy OCA], [http://pdbe.org/5ucy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ucy RCSB], [http://www.ebi.ac.uk/pdbsum/5ucy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ucy ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TBA_TETTH TBA_TETTH]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/TBB_TETTH TBB_TETTH]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Tetrahymena thermophila]]
		+	[[Category: Basu, K]]
		+	[[Category: Bui, K H]]
		+	[[Category: Ichikawa, M]]
		+	[[Category: Kastritis, P L]]
		+	[[Category: Liu, D]]
		+	[[Category: Cilia]]
		+	[[Category: Doublet]]
		+	[[Category: Protofilament]]
		+	[[Category: Structural protein]]
		+	[[Category: Tubulin]]

OCA at 14:21, 9 March 2017

OCA — Thu, 09 Mar 2017 14:21:49 GMT

←Older revision		Revision as of 14:21, 9 March 2017
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5ucy is ON HOLD	+	The entry 5ucy is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5ucy" [edit=sysop:move=sysop]

OCA — Wed, 04 Jan 2017 15:41:10 GMT

Protected "5ucy" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:41, 4 January 2017

OCA: New page: '''Unreleased structure''' The entry 5ucy is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 04 Jan 2017 15:41:09 GMT

New page: '''Unreleased structure''' The entry 5ucy is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5ucy is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]