5unk - Revision history

OCA at 10:26, 14 June 2023

OCA — Wed, 14 Jun 2023 10:26:35 GMT

←Older revision		Revision as of 10:26, 14 June 2023
Line 1:		Line 1:

	==NMR structure of the RED subdomain of the Sleeping Beauty transposase==		==NMR structure of the RED subdomain of the Sleeping Beauty transposase==
-	<StructureSection load='5unk' size='340' side='right'caption='[[5unk~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='5unk' size='340' side='right'caption='[[5unk]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5unk]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Oncmy Oncmy~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UNK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5UNK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5unk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oncorhynchus_mykiss Oncorhynchus mykiss]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UNK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UNK FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSONMT00020475001 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8022 ONCMY])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5unk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5unk OCA], [https://pdbe.org/5unk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5unk RCSB], [https://www.ebi.ac.uk/pdbsum/5unk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5unk ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5unk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5unk OCA], [~~http~~://pdbe.org/5unk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5unk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5unk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5unk ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A060ZAA1_ONCMY A0A060ZAA1_ONCMY]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 19:

	==See Also==		==See Also==
-	*[[Transposase\|Transposase]]	+	*[[Transposase 3D structures\|Transposase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Oncmy~~]]	+	[[Category: Oncorhynchus mykiss]]
-	[[Category: Konnova~~, T A~~]]	+	[[Category: Konnova TA]]
-	[[Category: Nesmelova~~, I V~~]]	+	[[Category: Nesmelova IV]]
-	[[Category: Singer~~, C M]]~~	+	[[Category: Singer CM]]
-	~~[[Category: Dna binding protein]]~~	+
-	~~[[Category: Dna-binding]]~~	+
-	~~[[Category: Helical]]~~	+
-	~~[[Category: Helix-turn-helix]]~~	+
-	~~[[Category: Transposase~~]]	+

OCA at 09:19, 1 January 2020

OCA — Wed, 01 Jan 2020 09:19:36 GMT

←Older revision		Revision as of 09:19, 1 January 2020
Line 1:		Line 1:

	==NMR structure of the RED subdomain of the Sleeping Beauty transposase==		==NMR structure of the RED subdomain of the Sleeping Beauty transposase==
-	<StructureSection load='5unk' size='340' side='right' caption='[[5unk]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='5unk' size='340' side='right'caption='[[5unk]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5unk]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UNK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UNK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5unk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oncmy Oncmy]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UNK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UNK FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5unk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5unk OCA], [http://pdbe.org/5unk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5unk RCSB], [http://www.ebi.ac.uk/pdbsum/5unk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5unk ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSONMT00020475001 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8022 ONCMY])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5unk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5unk OCA], [http://pdbe.org/5unk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5unk RCSB], [http://www.ebi.ac.uk/pdbsum/5unk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5unk ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	</div>		</div>
	<div class="pdbe-citations 5unk" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5unk" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Transposase\|Transposase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Oncmy]]
	[[Category: Konnova, T A]]		[[Category: Konnova, T A]]
	[[Category: Nesmelova, I V]]		[[Category: Nesmelova, I V]]

OCA at 10:40, 13 September 2017

OCA — Wed, 13 Sep 2017 10:40:22 GMT

←Older revision		Revision as of 10:40, 13 September 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5unk is ~~ON HOLD~~	+	==NMR structure of the RED subdomain of the Sleeping Beauty transposase==
		+	<StructureSection load='5unk' size='340' side='right' caption='[[5unk]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5unk]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UNK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UNK FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5unk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5unk OCA], [http://pdbe.org/5unk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5unk RCSB], [http://www.ebi.ac.uk/pdbsum/5unk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5unk ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	DNA transposons can be employed for stable gene transfer in vertebrates. The Sleeping Beauty (SB) DNA transposon has been recently adapted for human application and is being evaluated in clinical trials, however its molecular mechanism is not clear. SB transposition is catalyzed by the transposase enzyme, which is a multi-domain protein containing the catalytic and the DNA-binding domains. The DNA-binding domain of the SB transposase contains two structurally independent subdomains, PAI and RED. Recently, the structures of the catalytic domain and the PAI subdomain have been determined, however no structural information on the RED subdomain and its interactions with DNA has been available. Here, we used NMR spectroscopy to determine the solution structure of the RED subdomain and characterize its interactions with the transposon DNA.

-	~~Authors: Konnova, T.A~~., Singer, C.M.~~, Nesmelova, I~~.V.	+	NMR solution structure of the RED subdomain of the Sleeping Beauty transposase.,Konnova TA, Singer CM, Nesmelova IV Protein Sci. 2017 Jun;26(6):1171-1181. doi: 10.1002/pro.3167. Epub 2017 Apr 2. PMID:28345263<ref>PMID:28345263</ref>

-	~~Description: NMR structure~~ of the ~~RED subdomain~~ of ~~the Sleeping Beauty transposase~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
-	[[Category: Nesmelova, I.V]]	+	<div class="pdbe-citations 5unk" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Konnova~~, ~~T.A~~]]	+	== References ==
-	[[Category: ~~Singer, C.M~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Konnova, T A]]
		+	[[Category: Nesmelova, I V]]
		+	[[Category: Singer, C M]]
		+	[[Category: Dna binding protein]]
		+	[[Category: Dna-binding]]
		+	[[Category: Helical]]
		+	[[Category: Helix-turn-helix]]
		+	[[Category: Transposase]]

OCA at 19:13, 15 March 2017

OCA — Wed, 15 Mar 2017 19:13:07 GMT

←Older revision		Revision as of 19:13, 15 March 2017
Line 7:		Line 7:
	Description: NMR structure of the RED subdomain of the Sleeping Beauty transposase		Description: NMR structure of the RED subdomain of the Sleeping Beauty transposase
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Singer, C.M]]
	[[Category: Nesmelova, I.V]]		[[Category: Nesmelova, I.V]]
	[[Category: Konnova, T.A]]		[[Category: Konnova, T.A]]
		+	[[Category: Singer, C.M]]

OCA: Protected "5unk" [edit=sysop:move=sysop]

OCA — Thu, 09 Mar 2017 14:39:10 GMT

Protected "5unk" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:39, 9 March 2017

OCA: New page: '''Unreleased structure''' The entry 5unk is ON HOLD Authors: Konnova, T.A., Singer, C.M., Nesmelova, I.V. Description: NMR structure of the RED subdomain of the Sleeping Beauty transp...

OCA — Thu, 09 Mar 2017 14:39:09 GMT

New page: '''Unreleased structure''' The entry 5unk is ON HOLD Authors: Konnova, T.A., Singer, C.M., Nesmelova, I.V. Description: NMR structure of the RED subdomain of the Sleeping Beauty transp...

New page

'''Unreleased structure'''

The entry 5unk is ON HOLD

Authors: Konnova, T.A., Singer, C.M., Nesmelova, I.V.

Description: NMR structure of the RED subdomain of the Sleeping Beauty transposase
[[Category: Unreleased Structures]]
[[Category: Singer, C.M]]
[[Category: Nesmelova, I.V]]
[[Category: Konnova, T.A]]