5uvv - Revision history

OCA at 14:29, 6 March 2024

OCA — Wed, 06 Mar 2024 14:29:47 GMT

←Older revision		Revision as of 14:29, 6 March 2024
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	==BRD4 Bromodomain 2 with A-1457066==		==BRD4 Bromodomain 2 with A-1457066==
-	<StructureSection load='5uvv' size='340' side='right' caption='[[5uvv]], [[Resolution\|resolution]] 1.99Å' scene=''>	+	<StructureSection load='5uvv' size='340' side='right'caption='[[5uvv]], [[Resolution\|resolution]] 1.99Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5uvv]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UVV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5UVV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5uvv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UVV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UVV FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=8NS:7~~-~~(cyclopropylmethyl)-10-(ethylsulfonyl)-2-methyl-2~~,~~4,6,7-tetrahydro-3H-2,4,7-triazadibenzo~~[~~cd,f~~]~~azulen-3-one'>8NS</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.99Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[5uvs\|5uvs]]~~, ~~[[5uvu\|5uvu]]~~, ~~[[5uvt\|5uvt]]~~, ~~[[5uvx\|5uvx]]~~, ~~[[5uvy\|5uvy]]~~, [~~[5uvw\|5uvw]]~~, ~~[[5uvz\|5uvz~~]~~]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8NS:7-(cyclopropylmethyl)-10-(ethylsulfonyl)-2-methyl-2,4,6,7-tetrahydro-3H-2,4,7-triazadibenzo[cd,f]azulen-3-one'>8NS</scene></td></tr>
-	~~<tr id='gene~~'>~~<td class="sblockLbl"><b>[[Gene\|Gene:]]~~</b>~~</td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uvv OCA], [https://pdbe.org/5uvv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uvv RCSB], [https://www.ebi.ac.uk/pdbsum/5uvv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uvv ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5uvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uvv OCA], [~~http~~://pdbe.org/5uvv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5uvv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5uvv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5uvv ProSAT]</span></td></tr>	+
	</table>		</table>
	== Disease ==		== Disease ==
-	[~~[http~~://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>	+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).	+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
		+
		+	==See Also==
		+	*[[Bromodomain-containing protein 3D structures\|Bromodomain-containing protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Park, C H~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Helix bundle]]~~	+	[[Category: Park CH]]
-	~~[[Category: Signaling protein-inhibitor complex~~]]	+

OCA at 09:02, 16 November 2017

OCA — Thu, 16 Nov 2017 09:02:31 GMT

←Older revision		Revision as of 09:02, 16 November 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5uvv is ~~ON HOLD until Feb 20 2019~~	+	==BRD4 Bromodomain 2 with A-1457066==
-		+	<StructureSection load='5uvv' size='340' side='right' caption='[[5uvv]], [[Resolution\|resolution]] 1.99Å' scene=''>
-	~~Authors~~: ~~Park~~, C.H.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5uvv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UVV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UVV FirstGlance]. <br>
-	~~Description~~: BRD4 ~~Bromodomain 2~~ with A-~~1457066~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8NS:7-(cyclopropylmethyl)-10-(ethylsulfonyl)-2-methyl-2,4,6,7-tetrahydro-3H-2,4,7-triazadibenzo[cd,f]azulen-3-one'>8NS</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5uvs\|5uvs]], [[5uvu\|5uvu]], [[5uvt\|5uvt]], [[5uvx\|5uvx]], [[5uvy\|5uvy]], [[5uvw\|5uvw]], [[5uvz\|5uvz]]</td></tr>
-	[[Category: Park, C.H]]	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uvv OCA], [http://pdbe.org/5uvv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uvv RCSB], [http://www.ebi.ac.uk/pdbsum/5uvv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uvv ProSAT]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Park, C H]]
		+	[[Category: Helix bundle]]
		+	[[Category: Signaling protein-inhibitor complex]]

OCA: Protected "5uvv" [edit=sysop:move=sysop]

OCA — Thu, 09 Mar 2017 15:00:12 GMT

Protected "5uvv" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:00, 9 March 2017

OCA: New page: '''Unreleased structure''' The entry 5uvv is ON HOLD until Feb 20 2019 Authors: Park, C.H. Description: BRD4 Bromodomain 2 with A-1457066 Category: Unreleased Structures [[Category...

OCA — Thu, 09 Mar 2017 15:00:11 GMT

New page: '''Unreleased structure''' The entry 5uvv is ON HOLD until Feb 20 2019 Authors: Park, C.H. Description: BRD4 Bromodomain 2 with A-1457066 Category: Unreleased Structures [[Category...

New page

'''Unreleased structure'''

The entry 5uvv is ON HOLD until Feb 20 2019

Authors: Park, C.H.

Description: BRD4 Bromodomain 2 with A-1457066
[[Category: Unreleased Structures]]
[[Category: Park, C.H]]