5uxa - Revision history

OCA at 14:30, 6 March 2024

OCA — Wed, 06 Mar 2024 14:30:09 GMT

←Older revision		Revision as of 14:30, 6 March 2024
Line 3:		Line 3:
	<StructureSection load='5uxa' size='340' side='right'caption='[[5uxa]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='5uxa' size='340' side='right'caption='[[5uxa]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5uxa]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UXA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5UXA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5uxa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UXA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.95Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5uxb\|5uxb]]~~, [[~~5uxc~~\|~~5uxc]], [[5uxd\|5uxd~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>mphB, pO103_99 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~562~~ "~~Bacillus coli~~" ~~Migula 1895])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uxa OCA], [https://pdbe.org/5uxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uxa RCSB], [https://www.ebi.ac.uk/pdbsum/5uxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uxa ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5uxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uxa OCA], [~~http~~://pdbe.org/5uxa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5uxa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5uxa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5uxa ProSAT]</span></td></tr>	+
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/O32553_ECOLX O32553_ECOLX]
-	The production of antibiotics by microbes in the environment and their use in medicine and agriculture select for existing and emerging resistance. To address this inevitability, prudent development of antibiotic drugs requires careful consideration of resistance evolution. Here, we identify the molecular basis for expanded substrate specificity in MphI, a macrolide kinase (Mph) that does not confer resistance to erythromycin, in contrast to other known Mphs. Using a combination of phylogenetics, drug-resistance phenotypes, and in vitro enzyme assays, we find that MphI and MphK phosphorylate erythromycin poorly resulting in an antibiotic-sensitive phenotype. Using likelihood reconstruction of ancestral sequences and site-saturation combinatorial mutagenesis, supported by Mph crystal structures, we determine that two non-obvious mutations in combination expand the substrate range. This approach should be applicable for studying the functional evolution of any antibiotic resistance enzyme and for evaluating the evolvability of resistance enzymes to new generations of antibiotic scaffolds.	+
-		+
-	~~The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.,Pawlowski AC, Stogios PJ, Koteva K, Skarina T, Evdokimova E, Savchenko A, Wright GD Nat Commun. 2018 Jan 9;9(1)~~:~~112. doi: 10.1038~~/~~s41467-017-02680-0. PMID:29317655<ref>PMID:29317655<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 5uxa" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[Phosphotransferase 3D structures\|Phosphotransferase 3D structures]]		*[[Phosphotransferase 3D structures\|Phosphotransferase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Anderson~~, W F~~]]	+	[[Category: Anderson WF]]
-	[[Category: ~~Structural genomic~~]]	+	[[Category: Di Leo R]]
-	[[Category: Egorova, O]]	+	[[Category: Egorova O]]
-	[[Category: Evdokimova, E]]	+	[[Category: Evdokimova E]]
-	~~[[Category: Leo, R Di~~]]	+	[[Category: Savchenko A]]
-	[[Category: Savchenko, A]]	+	[[Category: Stogios PJ]]
-	[[Category: Stogios~~, P J~~]]	+	[[Category: Yim V]]
-	[[Category: Yim, V]]	+
-	~~[[Category: Antibiotic resistance]]~~	+
-	~~[[Category: Csgid]]~~	+
-	~~[[Category: Kinase]]~~	+
-	~~[[Category: Macrolide]]~~	+
-	~~[[Category: National institute of allergy and infectious disease]]~~	+
-	~~[[Category: Niaid]]~~	+
-	~~[[Category: Phosphotransferase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 17:12, 11 December 2019

OCA — Wed, 11 Dec 2019 17:12:34 GMT

←Older revision		Revision as of 17:12, 11 December 2019
Line 1:		Line 1:

	==Crystal structure of macrolide 2'-phosphotransferase MphB from Escherichia coli==		==Crystal structure of macrolide 2'-phosphotransferase MphB from Escherichia coli==
-	<StructureSection load='5uxa' size='340' side='right' caption='[[5uxa]], [[Resolution\|resolution]] 1.95Å' scene=''>	+	<StructureSection load='5uxa' size='340' side='right'caption='[[5uxa]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5uxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UXA FirstGlance]. <br>		<table><tr><td colspan='2'>[[5uxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UXA FirstGlance]. <br>
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Phosphotransferase\|Phosphotransferase]]	+	*[[Phosphotransferase 3D structures\|Phosphotransferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Anderson, W F]]		[[Category: Anderson, W F]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 08:21, 22 February 2018

OCA — Thu, 22 Feb 2018 08:21:36 GMT

←Older revision		Revision as of 08:21, 22 February 2018
Line 5:		Line 5:
	<table><tr><td colspan='2'>[[5uxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UXA FirstGlance]. <br>		<table><tr><td colspan='2'>[[5uxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UXA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5uxb\|5uxb]], [[5uxc\|5uxc]], [[5uxd\|5uxd]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mphB, pO103_99 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mphB, pO103_99 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uxa OCA], [http://pdbe.org/5uxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uxa RCSB], [http://www.ebi.ac.uk/pdbsum/5uxa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uxa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uxa OCA], [http://pdbe.org/5uxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uxa RCSB], [http://www.ebi.ac.uk/pdbsum/5uxa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uxa ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The production of antibiotics by microbes in the environment and their use in medicine and agriculture select for existing and emerging resistance. To address this inevitability, prudent development of antibiotic drugs requires careful consideration of resistance evolution. Here, we identify the molecular basis for expanded substrate specificity in MphI, a macrolide kinase (Mph) that does not confer resistance to erythromycin, in contrast to other known Mphs. Using a combination of phylogenetics, drug-resistance phenotypes, and in vitro enzyme assays, we find that MphI and MphK phosphorylate erythromycin poorly resulting in an antibiotic-sensitive phenotype. Using likelihood reconstruction of ancestral sequences and site-saturation combinatorial mutagenesis, supported by Mph crystal structures, we determine that two non-obvious mutations in combination expand the substrate range. This approach should be applicable for studying the functional evolution of any antibiotic resistance enzyme and for evaluating the evolvability of resistance enzymes to new generations of antibiotic scaffolds.
		+
		+	The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.,Pawlowski AC, Stogios PJ, Koteva K, Skarina T, Evdokimova E, Savchenko A, Wright GD Nat Commun. 2018 Jan 9;9(1):112. doi: 10.1038/s41467-017-02680-0. PMID:29317655<ref>PMID:29317655</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5uxa" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Phosphotransferase\|Phosphotransferase]]		*[[Phosphotransferase\|Phosphotransferase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:06, 31 January 2018

OCA — Wed, 31 Jan 2018 07:06:25 GMT

←Older revision		Revision as of 07:06, 31 January 2018
Line 3:		Line 3:
	<StructureSection load='5uxa' size='340' side='right' caption='[[5uxa]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='5uxa' size='340' side='right' caption='[[5uxa]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5uxa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UXA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5uxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UXA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mphB, pO103_99 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uxa OCA], [http://pdbe.org/5uxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uxa RCSB], [http://www.ebi.ac.uk/pdbsum/5uxa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uxa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uxa OCA], [http://pdbe.org/5uxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uxa RCSB], [http://www.ebi.ac.uk/pdbsum/5uxa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uxa ProSAT]</span></td></tr>
	</table>		</table>
Line 12:		Line 13:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus coli migula 1895]]
	[[Category: Anderson, W F]]		[[Category: Anderson, W F]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 08:24, 6 October 2017

OCA — Fri, 06 Oct 2017 08:24:56 GMT

←Older revision		Revision as of 08:24, 6 October 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5uxa is ~~ON HOLD~~	+	==Crystal structure of macrolide 2'-phosphotransferase MphB from Escherichia coli==
		+	<StructureSection load='5uxa' size='340' side='right' caption='[[5uxa]], [[Resolution\|resolution]] 1.95Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5uxa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UXA FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uxa OCA], [http://pdbe.org/5uxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uxa RCSB], [http://www.ebi.ac.uk/pdbsum/5uxa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uxa ProSAT]</span></td></tr>
		+	</table>

-	~~Authors~~: ~~Stogios, P.J., Evdokimova, E., Egorova, O., Di Leo, R., Yim, V., Savchenko, A.,~~ Anderson, W.F~~., Center for~~ Structural ~~Genomics of Infectious Diseases (CSGID)~~	+	==See Also==
-		+	*[[Phosphotransferase\|Phosphotransferase]]
-	~~Description~~: ~~Crystal structure of macrolide 2'-phosphotransferase MphB from Escherichia coli~~	+	__TOC__
-	[[Category: ~~Unreleased Structures~~]]	+	</StructureSection>
		+	[[Category: Anderson, W F]]
		+	[[Category: Structural genomic]]
		+	[[Category: Egorova, O]]
		+	[[Category: Evdokimova, E]]
		+	[[Category: Leo, R Di]]
	[[Category: Savchenko, A]]		[[Category: Savchenko, A]]
-	[[Category: ~~Egorova~~, O]]	+	[[Category: Stogios, P J]]
	[[Category: Yim, V]]		[[Category: Yim, V]]
-	[[Category: ~~Stogios, P.J~~]]	+	[[Category: Antibiotic resistance]]
-	[[Category: ~~Di Leo, R~~]]	+	[[Category: Csgid]]
-	[[Category: ~~Anderson, W.F~~]]	+	[[Category: Kinase]]
-	[[Category: ~~Center For Structural Genomics Of Infectious Diseases (Csgid)~~]]	+	[[Category: Macrolide]]
-	[[Category: ~~Evdokimova, E~~]]	+	[[Category: National institute of allergy and infectious disease]]
		+	[[Category: Niaid]]
		+	[[Category: Phosphotransferase]]
		+	[[Category: Transferase]]

OCA at 19:28, 15 March 2017

OCA — Wed, 15 Mar 2017 19:28:38 GMT

←Older revision		Revision as of 19:28, 15 March 2017
Line 7:		Line 7:
	Description: Crystal structure of macrolide 2'-phosphotransferase MphB from Escherichia coli		Description: Crystal structure of macrolide 2'-phosphotransferase MphB from Escherichia coli
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Egorova, O]]
	[[Category: Savchenko, A]]		[[Category: Savchenko, A]]
		+	[[Category: Egorova, O]]
	[[Category: Yim, V]]		[[Category: Yim, V]]
	[[Category: Stogios, P.J]]		[[Category: Stogios, P.J]]

OCA: Protected "5uxa" [edit=sysop:move=sysop]

OCA — Thu, 09 Mar 2017 15:03:25 GMT

Protected "5uxa" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:03, 9 March 2017

OCA: New page: '''Unreleased structure''' The entry 5uxa is ON HOLD Authors: Stogios, P.J., Evdokimova, E., Egorova, O., Di Leo, R., Yim, V., Savchenko, A., Anderson, W.F., Center for Structural Genom...

OCA — Thu, 09 Mar 2017 15:03:23 GMT

New page: '''Unreleased structure''' The entry 5uxa is ON HOLD Authors: Stogios, P.J., Evdokimova, E., Egorova, O., Di Leo, R., Yim, V., Savchenko, A., Anderson, W.F., Center for Structural Genom...

New page

'''Unreleased structure'''

The entry 5uxa is ON HOLD

Authors: Stogios, P.J., Evdokimova, E., Egorova, O., Di Leo, R., Yim, V., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

Description: Crystal structure of macrolide 2'-phosphotransferase MphB from Escherichia coli
[[Category: Unreleased Structures]]
[[Category: Egorova, O]]
[[Category: Savchenko, A]]
[[Category: Yim, V]]
[[Category: Stogios, P.J]]
[[Category: Di Leo, R]]
[[Category: Anderson, W.F]]
[[Category: Center For Structural Genomics Of Infectious Diseases (Csgid)]]
[[Category: Evdokimova, E]]