5uzs - Revision history

OCA at 09:25, 1 January 2020

OCA — Wed, 01 Jan 2020 09:25:19 GMT

←Older revision		Revision as of 09:25, 1 January 2020
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	==Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200==		==Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200==
-	<StructureSection load='5uzs' size='340' side='right' caption='[[5uzs]], [[Resolution\|resolution]] 2.37Å' scene=''>	+	<StructureSection load='5uzs' size='340' side='right'caption='[[5uzs]], [[Resolution\|resolution]] 2.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5uzs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clop1 Clop1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UZS FirstGlance]. <br>		<table><tr><td colspan='2'>[[5uzs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clop1 Clop1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UZS FirstGlance]. <br>
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	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/A0A0H2YRZ7_CLOP1 A0A0H2YRZ7_CLOP1]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]		[[http://www.uniprot.org/uniprot/A0A0H2YRZ7_CLOP1 A0A0H2YRZ7_CLOP1]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]
		+
		+	==See Also==
		+	*[[Inosine monophosphate dehydrogenase 3D structures\|Inosine monophosphate dehydrogenase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Clop1]]		[[Category: Clop1]]
	[[Category: IMP dehydrogenase]]		[[Category: IMP dehydrogenase]]
		+	[[Category: Large Structures]]
	[[Category: Anderson, W F]]		[[Category: Anderson, W F]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 19:50, 15 November 2017

OCA — Wed, 15 Nov 2017 19:50:02 GMT

←Older revision		Revision as of 19:50, 15 November 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5uzs ~~is ON HOLD~~	+	==Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200==
-		+	<StructureSection load='5uzs' size='340' side='right' caption='[[5uzs]], [[Resolution\|resolution]] 2.37Å' scene=''>
-	~~Authors~~: ~~Maltseva, N~~., ~~Kim~~, Y., ~~Mulligan~~, R., ~~Makowska~~-~~Grzyska~~, M., Gu, M., ~~Gollapalli~~, D.R., ~~Hedstrom~~, L., ~~Joachimiak~~, A., ~~Anderson, W~~.F., ~~Center for Structural Genomics of Infectious Diseases (CSGID)~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5uzs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clop1 Clop1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UZS FirstGlance]. <br>
-	~~Description~~: ~~Crystal Structure~~ of ~~Inosine~~ 5'-~~monophosphate Dehydrogenase from Clostridium perfringens Complexed with~~ IMP and ~~P200~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8L4:3-(2-{[(4-CHLOROPHENYL)CARBAMOYL]AMINO}PROPAN-2-YL)-N-HYDROXYBENZENE-1-CARBOXIMIDAMIDE'>8L4</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene></td></tr>
-	[[Category: Gollapalli, D.R]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4q32\|4q32]], [[4q33\|4q33]], [[5uwx\|5uwx]], [[5uxe\|5uxe]], [[5uze\|5uze]], [[5uzc\|5uzc]], [[5uzo\|5uzo]]</td></tr>
-	[[Category: ~~Mulligan~~, R]]	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">guaB, CPF_2558 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=195103 CLOP1])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uzs OCA], [http://pdbe.org/5uzs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uzs RCSB], [http://www.ebi.ac.uk/pdbsum/5uzs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uzs ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/A0A0H2YRZ7_CLOP1 A0A0H2YRZ7_CLOP1]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Clop1]]
		+	[[Category: IMP dehydrogenase]]
		+	[[Category: Anderson, W F]]
		+	[[Category: Structural genomic]]
		+	[[Category: Gollapalli, D R]]
		+	[[Category: Gu, M]]
		+	[[Category: Hedstrom, L]]
		+	[[Category: Joachimiak, A]]
		+	[[Category: Kim, Y]]
	[[Category: Makowska-Grzyska, M]]		[[Category: Makowska-Grzyska, M]]
	[[Category: Maltseva, N]]		[[Category: Maltseva, N]]
-	[[Category: ~~Joachimiak~~, A]]	+	[[Category: Mulligan, R]]
-	[[Category: ~~Hedstrom, L~~]]	+	[[Category: Csgid]]
-	[[Category: ~~Anderson, W.F~~]]	+	[[Category: Impdh]]
-	[[Category: ~~Gu, M~~]]	+	[[Category: Oxidoreductase]]
-	[[Category: ~~Center For Structural Genomics Of Infectious Diseases (Csgid)~~]]	+	[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
-	[[Category: ~~Kim, Y~~]]	+	[[Category: Tim barrel]]

OCA at 19:33, 15 March 2017

OCA — Wed, 15 Mar 2017 19:33:38 GMT

←Older revision		Revision as of 19:33, 15 March 2017
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	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Gollapalli, D.R]]		[[Category: Gollapalli, D.R]]
-	[[Category: Joachimiak, A]]
	[[Category: Mulligan, R]]		[[Category: Mulligan, R]]
	[[Category: Makowska-Grzyska, M]]		[[Category: Makowska-Grzyska, M]]
	[[Category: Maltseva, N]]		[[Category: Maltseva, N]]
		+	[[Category: Joachimiak, A]]
	[[Category: Hedstrom, L]]		[[Category: Hedstrom, L]]
	[[Category: Anderson, W.F]]		[[Category: Anderson, W.F]]

OCA: Protected "5uzs" [edit=sysop:move=sysop]

OCA — Thu, 09 Mar 2017 15:09:03 GMT

Protected "5uzs" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:09, 9 March 2017

OCA: New page: '''Unreleased structure''' The entry 5uzs is ON HOLD Authors: Maltseva, N., Kim, Y., Mulligan, R., Makowska-Grzyska, M., Gu, M., Gollapalli, D.R., Hedstrom, L., Joachimiak, A., Anderson...

OCA — Thu, 09 Mar 2017 15:09:02 GMT

New page: '''Unreleased structure''' The entry 5uzs is ON HOLD Authors: Maltseva, N., Kim, Y., Mulligan, R., Makowska-Grzyska, M., Gu, M., Gollapalli, D.R., Hedstrom, L., Joachimiak, A., Anderson...

New page

'''Unreleased structure'''

The entry 5uzs is ON HOLD

Authors: Maltseva, N., Kim, Y., Mulligan, R., Makowska-Grzyska, M., Gu, M., Gollapalli, D.R., Hedstrom, L., Joachimiak, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

Description: Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200
[[Category: Unreleased Structures]]
[[Category: Gollapalli, D.R]]
[[Category: Joachimiak, A]]
[[Category: Mulligan, R]]
[[Category: Makowska-Grzyska, M]]
[[Category: Maltseva, N]]
[[Category: Hedstrom, L]]
[[Category: Anderson, W.F]]
[[Category: Gu, M]]
[[Category: Center For Structural Genomics Of Infectious Diseases (Csgid)]]
[[Category: Kim, Y]]