5v0p - Revision history

OCA at 13:38, 4 October 2023

OCA — Wed, 04 Oct 2023 13:38:50 GMT

←Older revision		Revision as of 13:38, 4 October 2023
Line 3:		Line 3:
	<StructureSection load='5v0p' size='340' side='right'caption='[[5v0p]], [[Resolution\|resolution]] 2.16Å' scene=''>		<StructureSection load='5v0p' size='340' side='right'caption='[[5v0p]], [[Resolution\|resolution]] 2.16Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5v0p]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Vibch Vibch~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V0P OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5V0P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5v0p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V0P FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=CO8:OCTANOYL~~-~~COENZYME+A'>CO8</scene>~~, ~~<scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.16Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>fabH2, VC_A0751 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~243277 VIBCH])</td~~><~~/tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO8:OCTANOYL-COENZYME+A'>CO8</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_III Beta-ketoacyl-[acyl-carrier-protein] synthase III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.180 2.3.1.180] </~~span~~></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v0p OCA], [https://pdbe.org/5v0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v0p RCSB], [https://www.ebi.ac.uk/pdbsum/5v0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v0p ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5v0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v0p OCA], [~~http~~://pdbe.org/5v0p PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5v0p RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5v0p PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5v0p ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/FABH2_VIBCH FABH2_VIBCH]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.[HAMAP-Rule:MF_01815]	+	[https://www.uniprot.org/uniprot/FABH2_VIBCH FABH2_VIBCH] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.[HAMAP-Rule:MF_01815]

	==See Also==		==See Also==
Line 17:		Line 16:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Vibch~~]]	+	[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
-	[[Category: Anderson~~, W F]]~~	+	[[Category: Anderson WF]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Cooper DR]]
-	[[Category: Cooper~~, D R~~]]	+	[[Category: Grabowski M]]
-	[[Category: Grabowski, M]]	+	[[Category: Hou J]]
-	[[Category: Hou, J]]	+	[[Category: Minor W]]
-	[[Category: Minor, W]]	+	[[Category: Zheng H]]
-	[[Category: Zheng, H]]	+
-	~~[[Category: Beta-ketoacyl-acyl carrier protein synthase iii]]~~	+
-	~~[[Category: Csgid]]~~	+
-	~~[[Category: Fabh]]~~	+
-	~~[[Category: Octanoyl-coa]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 17:13, 11 December 2019

OCA — Wed, 11 Dec 2019 17:13:04 GMT

←Older revision		Revision as of 17:13, 11 December 2019
Line 1:		Line 1:

	==Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA==		==Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA==
-	<StructureSection load='5v0p' size='340' side='right' caption='[[5v0p]], [[Resolution\|resolution]] 2.16Å' scene=''>	+	<StructureSection load='5v0p' size='340' side='right'caption='[[5v0p]], [[Resolution\|resolution]] 2.16Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5v0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V0P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5v0p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibch Vibch]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V0P FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO8:OCTANOYL-COENZYME+A'>CO8</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO8:OCTANOYL-COENZYME+A'>CO8</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabH2, VC_A0751 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243277 VIBCH])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_III Beta-ketoacyl-[acyl-carrier-protein] synthase III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.180 2.3.1.180] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_III Beta-ketoacyl-[acyl-carrier-protein] synthase III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.180 2.3.1.180] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v0p OCA], [http://pdbe.org/5v0p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v0p RCSB], [http://www.ebi.ac.uk/pdbsum/5v0p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v0p ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v0p OCA], [http://pdbe.org/5v0p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v0p RCSB], [http://www.ebi.ac.uk/pdbsum/5v0p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v0p ProSAT]</span></td></tr>
Line 10:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/FABH2_VIBCH FABH2_VIBCH]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.[HAMAP-Rule:MF_01815]		[[http://www.uniprot.org/uniprot/FABH2_VIBCH FABH2_VIBCH]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.[HAMAP-Rule:MF_01815]
		+
		+	==See Also==
		+	*[[Acyl carrier protein synthase 3D structures\|Acyl carrier protein synthase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Vibch]]
	[[Category: Anderson, W F]]		[[Category: Anderson, W F]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 16:48, 22 March 2017

OCA — Wed, 22 Mar 2017 16:48:21 GMT

←Older revision		Revision as of 16:48, 22 March 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5v0p ~~is ON HOLD~~	+	==Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA==
-		+	<StructureSection load='5v0p' size='340' side='right' caption='[[5v0p]], [[Resolution\|resolution]] 2.16Å' scene=''>
-	~~Authors~~: ~~Hou~~, J., ~~Zheng, H~~., ~~Cooper, D~~.R., ~~Grabowski, M~~., ~~Anderson, W~~.F., ~~Minor, W~~., ~~Center for Structural Genomics of Infectious Diseases (CSGID)~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5v0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V0P FirstGlance]. <br>
-	~~Description~~: ~~Crystal Structure~~ of ~~Beta~~-~~ketoacyl~~-ACP synthase ~~III~~-~~2 (FabH2) (C113A) from Vibrio Cholerae co~~-~~crystallized with octanoyl~~-~~CoA~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO8:OCTANOYL-COENZYME+A'>CO8</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_III Beta-ketoacyl-[acyl-carrier-protein] synthase III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.180 2.3.1.180] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v0p OCA], [http://pdbe.org/5v0p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v0p RCSB], [http://www.ebi.ac.uk/pdbsum/5v0p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v0p ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FABH2_VIBCH FABH2_VIBCH]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.[HAMAP-Rule:MF_01815]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Anderson, W F]]
		+	[[Category: Structural genomic]]
		+	[[Category: Cooper, D R]]
		+	[[Category: Grabowski, M]]
	[[Category: Hou, J]]		[[Category: Hou, J]]
		+	[[Category: Minor, W]]
	[[Category: Zheng, H]]		[[Category: Zheng, H]]
-	[[Category: ~~Anderson, W.F~~]]	+	[[Category: Beta-ketoacyl-acyl carrier protein synthase iii]]
-	[[Category: ~~Grabowski, M~~]]	+	[[Category: Csgid]]
-	[[Category: ~~Center For Structural Genomics Of Infectious Diseases (Csgid)~~]]	+	[[Category: Fabh]]
-	[[Category: ~~Cooper, D.R~~]]	+	[[Category: Octanoyl-coa]]
-	[[Category: ~~Minor, W~~]]	+	[[Category: Transferase]]

OCA at 19:35, 15 March 2017

OCA — Wed, 15 Mar 2017 19:35:10 GMT

←Older revision		Revision as of 19:35, 15 March 2017
Line 7:		Line 7:
	Description: Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA		Description: Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Zheng, H]]
-	[[Category: Minor, W]]
	[[Category: Hou, J]]		[[Category: Hou, J]]
		+	[[Category: Zheng, H]]
	[[Category: Anderson, W.F]]		[[Category: Anderson, W.F]]
	[[Category: Grabowski, M]]		[[Category: Grabowski, M]]
	[[Category: Center For Structural Genomics Of Infectious Diseases (Csgid)]]		[[Category: Center For Structural Genomics Of Infectious Diseases (Csgid)]]
	[[Category: Cooper, D.R]]		[[Category: Cooper, D.R]]
		+	[[Category: Minor, W]]

OCA: Protected "5v0p" [edit=sysop:move=sysop]

OCA — Thu, 09 Mar 2017 15:11:34 GMT

Protected "5v0p" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:11, 9 March 2017

OCA: New page: '''Unreleased structure''' The entry 5v0p is ON HOLD Authors: Hou, J., Zheng, H., Cooper, D.R., Grabowski, M., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Di...

OCA — Thu, 09 Mar 2017 15:11:32 GMT

New page: '''Unreleased structure''' The entry 5v0p is ON HOLD Authors: Hou, J., Zheng, H., Cooper, D.R., Grabowski, M., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Di...

New page

'''Unreleased structure'''

The entry 5v0p is ON HOLD

Authors: Hou, J., Zheng, H., Cooper, D.R., Grabowski, M., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

Description: Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA
[[Category: Unreleased Structures]]
[[Category: Zheng, H]]
[[Category: Minor, W]]
[[Category: Hou, J]]
[[Category: Anderson, W.F]]
[[Category: Grabowski, M]]
[[Category: Center For Structural Genomics Of Infectious Diseases (Csgid)]]
[[Category: Cooper, D.R]]