5v54 - Revision history

OCA at 08:31, 30 September 2020

OCA — Wed, 30 Sep 2020 08:31:15 GMT

←Older revision		Revision as of 08:31, 30 September 2020
Line 1:		Line 1:

	==Crystal structure of 5-HT1B receptor in complex with methiothepin==		==Crystal structure of 5-HT1B receptor in complex with methiothepin==
-	<StructureSection load='5v54' size='340' side='right' caption='[[5v54]], [[Resolution\|resolution]] 3.90Å' scene=''>	+	<StructureSection load='5v54' size='340' side='right'caption='[[5v54]], [[Resolution\|resolution]] 3.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5v54]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5V54 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5v54]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5V54 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5v54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v54 OCA], [http://pdbe.org/5v54 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v54 RCSB], [http://www.ebi.ac.uk/pdbsum/5v54 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v54 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5v54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v54 OCA], [http://pdbe.org/5v54 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v54 RCSB], [http://www.ebi.ac.uk/pdbsum/5v54 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v54 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.		[[http://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
		+
		+	==See Also==
		+	*[[5-hydroxytryptamine receptor 3D structures\|5-hydroxytryptamine receptor 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Caffrey, M]]		[[Category: Caffrey, M]]
	[[Category: Cai, X]]		[[Category: Cai, X]]

OCA at 06:13, 7 February 2018

OCA — Wed, 07 Feb 2018 06:13:28 GMT

←Older revision		Revision as of 06:13, 7 February 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5v54 ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of 5-HT1B receptor in complex with methiothepin==
-		+	<StructureSection load='5v54' size='340' side='right' caption='[[5v54]], [[Resolution\|resolution]] 3.90Å' scene=''>
-	~~Authors~~: ~~Yin, W~~.C.~~, Zhou, X~~.E.~~, Yang, D~~.~~, de Waal, P~~.~~, Wang, M~~.T.~~, Dai, A~~., ~~Cai, X~~.~~, Huang, C~~.Y.~~, Liu, P~~., ~~Yin, Y~~.~~, Liu, B~~.~~, Caffrey, M~~., ~~Melcher, K~~., ~~Xu, Y~~.~~, Wang, M~~.W., ~~Xu, H~~.E., ~~Jiang, Y~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5v54]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V54 FirstGlance]. <br>
-	~~Description: Crystal structure of 5-HT1B receptor in complex with methiothepin~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v54 OCA], [http://pdbe.org/5v54 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v54 RCSB], [http://www.ebi.ac.uk/pdbsum/5v54 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v54 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
		+	__TOC__
		+	</StructureSection>
	[[Category: Caffrey, M]]		[[Category: Caffrey, M]]
-	[[Category: ~~Zhou~~, X~~.E]]~~	+	[[Category: Cai, X]]
-	~~[[Category: Xu, H.E~~]]	+
	[[Category: Dai, A]]		[[Category: Dai, A]]
-	~~[[Category: Wang, M.T]]~~	+	[[Category: Huang, C Y]]
-	~~[[Category: Melcher, K]]~~	+
-	~~[[Category: Yin, W.C]]~~	+
-	~~[[Category: Yang, D]]~~	+
-	[[Category: Huang, C~~.Y]]~~	+
-	~~[[Category: Wang, M.W]]~~	+
-	~~[[Category: Yin,~~ Y]]	+
	[[Category: Jiang, Y]]		[[Category: Jiang, Y]]
	[[Category: Liu, B]]		[[Category: Liu, B]]
	[[Category: Liu, P]]		[[Category: Liu, P]]
		+	[[Category: Melcher, K]]
		+	[[Category: Waal, P de]]
		+	[[Category: Wang, M T]]
		+	[[Category: Wang, M W]]
		+	[[Category: Xu, H E]]
	[[Category: Xu, Y]]		[[Category: Xu, Y]]
-	[[Category: ~~Cai~~, X]]	+	[[Category: Yang, D]]
-	[[Category: ~~De Waal~~, P]]	+	[[Category: Yin, W C]]
		+	[[Category: Yin, Y]]
		+	[[Category: Zhou, X E]]
		+	[[Category: 5-hydroxytryptamine]]
		+	[[Category: Electron transport]]
		+	[[Category: Gpcr antagonist]]
		+	[[Category: Ob1]]

OCA at 17:08, 24 January 2018

OCA — Wed, 24 Jan 2018 17:08:22 GMT

←Older revision		Revision as of 17:08, 24 January 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5v54 is ON HOLD	+	The entry 5v54 is ON HOLD until Paper Publication

	Authors: Yin, W.C., Zhou, X.E., Yang, D., de Waal, P., Wang, M.T., Dai, A., Cai, X., Huang, C.Y., Liu, P., Yin, Y., Liu, B., Caffrey, M., Melcher, K., Xu, Y., Wang, M.W., Xu, H.E., Jiang, Y.		Authors: Yin, W.C., Zhou, X.E., Yang, D., de Waal, P., Wang, M.T., Dai, A., Cai, X., Huang, C.Y., Liu, P., Yin, Y., Liu, B., Caffrey, M., Melcher, K., Xu, Y., Wang, M.W., Xu, H.E., Jiang, Y.
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	Description: Crystal structure of 5-HT1B receptor in complex with methiothepin		Description: Crystal structure of 5-HT1B receptor in complex with methiothepin
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Caffrey, M]]
	[[Category: Zhou, X.E]]		[[Category: Zhou, X.E]]
	[[Category: Xu, H.E]]		[[Category: Xu, H.E]]
	[[Category: Dai, A]]		[[Category: Dai, A]]
		+	[[Category: Wang, M.T]]
	[[Category: Melcher, K]]		[[Category: Melcher, K]]
-	[[Category: Yang, D]]
-	[[Category: Jiang, Y]]
-	[[Category: Liu, P]]
-	[[Category: Xu, Y]]
-	[[Category: Caffrey, M]]
	[[Category: Yin, W.C]]		[[Category: Yin, W.C]]
		+	[[Category: Yang, D]]
	[[Category: Huang, C.Y]]		[[Category: Huang, C.Y]]
-	~~[[Category: De Waal, P]]~~	+	[[Category: Wang, M.W]]
-	[[Category: Wang, M.T]]	+
	[[Category: Yin, Y]]		[[Category: Yin, Y]]
		+	[[Category: Jiang, Y]]
	[[Category: Liu, B]]		[[Category: Liu, B]]
-	[[Category: ~~Wang~~, ~~M.W~~]]	+	[[Category: Liu, P]]
		+	[[Category: Xu, Y]]
	[[Category: Cai, X]]		[[Category: Cai, X]]
		+	[[Category: De Waal, P]]

OCA at 13:53, 27 September 2017

OCA — Wed, 27 Sep 2017 13:53:48 GMT

←Older revision		Revision as of 13:53, 27 September 2017
Line 10:		Line 10:
	[[Category: Xu, H.E]]		[[Category: Xu, H.E]]
	[[Category: Dai, A]]		[[Category: Dai, A]]
-	[[Category: Wang, M.T]]
	[[Category: Melcher, K]]		[[Category: Melcher, K]]
	[[Category: Yang, D]]		[[Category: Yang, D]]
-	[[Category: Yin, Y]]
	[[Category: Jiang, Y]]		[[Category: Jiang, Y]]
-	[[Category: Liu, B]]
	[[Category: Liu, P]]		[[Category: Liu, P]]
	[[Category: Xu, Y]]		[[Category: Xu, Y]]
Line 21:		Line 18:
	[[Category: Yin, W.C]]		[[Category: Yin, W.C]]
	[[Category: Huang, C.Y]]		[[Category: Huang, C.Y]]
		+	[[Category: De Waal, P]]
		+	[[Category: Wang, M.T]]
		+	[[Category: Yin, Y]]
		+	[[Category: Liu, B]]
	[[Category: Wang, M.W]]		[[Category: Wang, M.W]]
	[[Category: Cai, X]]		[[Category: Cai, X]]
-	[[Category: De Waal, P]]

OCA at 11:13, 24 May 2017

OCA — Wed, 24 May 2017 11:13:57 GMT

←Older revision		Revision as of 11:13, 24 May 2017
Line 3:		Line 3:
	The entry 5v54 is ON HOLD		The entry 5v54 is ON HOLD

-	Authors: Yin, W.-C., Zhou, X. E., Yang, D., de Waal, P., Wang, M.-T., Dai, A., Cai, X., Huang, C.-Y., Liu, P., Yin, Y., Liu, B., Caffrey, M., Melcher, K., Xu, Y., Wang, M.-W., Xu, H.E., Jiang, Y.	+	Authors: Yin, W.C., Zhou, X.E., Yang, D., de Waal, P., Wang, M.T., Dai, A., Cai, X., Huang, C.Y., Liu, P., Yin, Y., Liu, B., Caffrey, M., Melcher, K., Xu, Y., Wang, M.W., Xu, H.E., Jiang, Y.

	Description: Crystal structure of 5-HT1B receptor in complex with methiothepin		Description: Crystal structure of 5-HT1B receptor in complex with methiothepin
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Zhou, X.E]]
	[[Category: Xu, H.E]]		[[Category: Xu, H.E]]
	[[Category: Dai, A]]		[[Category: Dai, A]]
		+	[[Category: Wang, M.T]]
	[[Category: Melcher, K]]		[[Category: Melcher, K]]
	[[Category: Yang, D]]		[[Category: Yang, D]]
Line 15:		Line 17:
	[[Category: Liu, B]]		[[Category: Liu, B]]
	[[Category: Liu, P]]		[[Category: Liu, P]]
-	[[Category: Zhou, X. E]]
	[[Category: Xu, Y]]		[[Category: Xu, Y]]
	[[Category: Caffrey, M]]		[[Category: Caffrey, M]]
-	[[Category: ~~Wang~~, M.-T]]	+	[[Category: Yin, W.C]]
-	[[Category: Huang, C.-Y]]	+	[[Category: Huang, C.Y]]
-	[[Category: Wang, M.-W]]	+	[[Category: Wang, M.W]]
-	~~[[Category: Yin, W.-C~~]]	+
	[[Category: Cai, X]]		[[Category: Cai, X]]
	[[Category: De Waal, P]]		[[Category: De Waal, P]]

OCA: Protected "5v54" [edit=sysop:move=sysop]

OCA — Wed, 05 Apr 2017 11:36:25 GMT

Protected "5v54" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:36, 5 April 2017

OCA: New page: '''Unreleased structure''' The entry 5v54 is ON HOLD Authors: Yin, W.-C., Zhou, X. E., Yang, D., de Waal, P., Wang, M.-T., Dai, A., Cai, X., Huang, C.-Y., Liu, P., Yin, Y., Liu, B., Caf...

OCA — Wed, 05 Apr 2017 11:36:23 GMT

New page: '''Unreleased structure''' The entry 5v54 is ON HOLD Authors: Yin, W.-C., Zhou, X. E., Yang, D., de Waal, P., Wang, M.-T., Dai, A., Cai, X., Huang, C.-Y., Liu, P., Yin, Y., Liu, B., Caf...

New page

'''Unreleased structure'''

The entry 5v54 is ON HOLD

Authors: Yin, W.-C., Zhou, X. E., Yang, D., de Waal, P., Wang, M.-T., Dai, A., Cai, X., Huang, C.-Y., Liu, P., Yin, Y., Liu, B., Caffrey, M., Melcher, K., Xu, Y., Wang, M.-W., Xu, H.E., Jiang, Y.

Description: Crystal structure of 5-HT1B receptor in complex with methiothepin
[[Category: Unreleased Structures]]
[[Category: Xu, H.E]]
[[Category: Dai, A]]
[[Category: Melcher, K]]
[[Category: Yang, D]]
[[Category: Yin, Y]]
[[Category: Jiang, Y]]
[[Category: Liu, B]]
[[Category: Liu, P]]
[[Category: Zhou, X. E]]
[[Category: Xu, Y]]
[[Category: Caffrey, M]]
[[Category: Wang, M.-T]]
[[Category: Huang, C.-Y]]
[[Category: Wang, M.-W]]
[[Category: Yin, W.-C]]
[[Category: Cai, X]]
[[Category: De Waal, P]]